[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100614575":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":25,"responsibleParty":39,"collaborators":41,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":25,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":52,"minAge":53,"maxAge":25,"enrollmentInfo":54,"targetDuration":25,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":66,"overallStatus":73,"whyStopped":25,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":25},{"fullName":5,"class":6},"University of Florida","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Attention-Control condition","Participants randomized to the control condition will have six 1-on-1 sessions with a facilitator engaging in writing exercises. The sessions will be comparable in length to the intervention sessions but will not include any skills practice. Each session will include a neutral writing exercises.",[12],"Behavioral: Contingency Management",{"label":14,"type":15,"description":16,"interventionNames":17},"Experimental condition","EXPERIMENTAL","Participants randomized to the experimental condition (tailored behavioral intervention) will have a 1-on-1 session with a facilitator. The intervention consists of six individually delivered sessions (1-2 sessions per week, approximately 1.5 hours each). The intervention will be interactive and include rapport- and trust-building activities; didactic teaching; multimedia (e.g., videos) messages to facilitate modeling and discussion; role-playing and skills building, practice, and feedback. The intervention will be led by a CITI certified facilitator, who is also a member of the study team. The sessions are: (1) Positive affect skills; (2) Positive Conscious Networks broaden and building supportive personal networks; (3) Mindfulness; (4) Personal Strengths and Obtainable Goals; (5) Positive Reassessment; and (6) Compassion\u002Fsolidarity to one-self as to others. Sessions\u002Fmodules will be guided by Segmented Assimilation and Stress and Coping Theory.",[18,12],"Behavioral: Tailored Positive Affect Intervention",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Tailored Positive Affect Intervention","The intervention consists of six individually delivered sessions (1-2 sessions per week, approximately 1.5 hours each). The intervention will be interactive and include rapport- and trust-building activities; didactic teaching; multimedia (e.g., videos) messages to facilitate modeling and discussion; role-playing and skills building, practice, and feedback. T\n\nThe sessions are: (1) Positive affect skills; (2) Positive Conscious Networks broaden and building supportive personal networks;(3) Mindfulness; (4) Personal Strengths and Obtainable Goals; (5) Positive Reassessment; and (6) Compassion\u002Fsolidarity to one-self as to others. Sessions\u002Fmodules will be guided by Segmented Assimilation and Stress and Coping Theory.",[14],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Contingency Management","Incentives will be provided as positive reinforcement of two key behaviors that are crucial to increase PrEP uptake. First, participants will receive incentives for documented evidence that they have completed a medical visit for PrEP clinical evaluation (including HIV testing). Second, participants completing PrEP clinical evaluation will receive incentives when they document evidence of an active prescription of PrEP.",[9,14],[31],{"name":32,"affiliation":5,"role":33},"Jose Colon-Burgos, DrPH","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","(352) 273-9188","jcolonburgos@phhp.ufl.edu",{"type":40,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[42],{"name":43,"class":44},"National Institute on Drug Abuse (NIDA)","NIH","100614575","reducing-co-occurring-substance-use-and-hiv-risk-among-stimulant-using-men-at-high-risk-for-hiv-in-the-united-states-of-america-100614575",false,"NCT07281378","Reducing Co-occurring Substance Use and HIV Risk Among Stimulant-using Men at High Risk for HIV in the United States of America.","Inclusion Criteria:\n\n1. be 18 years of age or older;\n2. be sexually active cisgender men at high risk for HIV (foreign and US-born, residing in the US)-reporting any condomless anal sex (CAS) in the past three months with a man;\n3. report use of stimulant (i.e., methamphetamine, powder cocaine, or crack-cocaine) at least one day in the past three or six month;\n4. have HIV-negative serostatus;\n5. be bilingual (Spanish and English), or Spanish or English monolingual;\n6. meet CDC criteria for PrEP eligibility.\n\nExclusion Criteria:\n\n1. display diminished capacity to consent (e.g., cognitive impairment); or\n2. severe psychiatric symptoms (e.g., psychosis) that require more intensive treatment;\n3. if they are HIV positive or living with HIV;\n4. if they are already taking PrEP; and\n5. if the participant can't consent to participate in English or Spanish.",true,"MALE","18 Years",{"count":55,"type":56},84,"ESTIMATED","INTERVENTIONAL",[59],"NA","This intervention will focus on stimulant-using men at high risk for HIV who are in need of tailored behavioral interventions to mitigate co-occurring stimulant use and HIV risk in the era of pre-exposure prophylaxis (PrEP). The study is a pilot randomized controlled trial to evaluate the adaptation, feasibility, acceptability, and preliminary efficacy of a behavioral intervention.",[62,63,64,65],"Drug Use Disorders","PrEP Uptake","PrEP Adherence","HIV Risk Behavior",[67,68,69,70,71,72],"PrEP","PrEP uptake","HIV","substance use","stimulant use","men at high risk for HIV","NOT_YET_RECRUITING","2026-06-29",{"date":76,"type":77},"2026-06-30","ACTUAL",{"date":79,"type":56},"2026-07-20",{"date":81,"type":56},"2027-12-31",{"name":5,"class":6}]