[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100592001":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":26,"locations":37,"responsibleParty":58,"collaborators":61,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":31,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":31,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":91,"whyStopped":31,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"McMaster University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"BCI training and testing group","EXPERIMENTAL","This group will contain all participants. All participants will receive the same rTMS brain stimulation, a series of 90 triplet pulses at 100 Hz.",[13],"Device: Repetitive transcranial magnetic stimulation",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","Repetitive transcranial magnetic stimulation","Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive, non-painful procedure used to relieve chronic pain and promote short-term changes. The first dorsal interossei (FDI) muscle of the left motor cortex will be targeted using neuronavigation software. A series of 90 triplet pulses will be delivered at 100 Hz stimulation. Stimulation will be delivered at 80% of the resting motor threshold obtained from the right FDI muscle. The delivery of rTMS requires \\~ 15 minutes in total.",[9],[21],"rTMS",[23],{"name":24,"affiliation":5,"role":25},"Aimee J Nelson, PhD","PRINCIPAL_INVESTIGATOR",[27,33],{"name":28,"role":29,"phone":30,"phoneExt":31,"email":32},"Amandeep K Atwal, BSc Science","CONTACT","6476330118",null,"atwala9@mcmaster.ca",{"name":34,"role":29,"phone":35,"phoneExt":31,"email":36},"Stevie Foglia, PhD","9053920144","foglias@mcmaster.ca",[38],{"facility":5,"status":31,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Hamilton","Ontario","L8S 4L8","Canada","CA",{"type":45,"coordinates":46},"Point",[47,48],-79.84963,43.25011,{"lat":48,"lon":47},[51,55,56],{"name":24,"role":29,"phone":52,"phoneExt":53,"email":54},"9055259140","28053","nelsonaj@mcmaster.ca",{"name":34,"role":29,"phone":35,"phoneExt":31,"email":36},{"name":28,"role":57,"phone":31,"phoneExt":31,"email":31},"SUB_INVESTIGATOR",{"type":25,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"Aimee Nelson","Local Principal Investigator",[62],{"name":63,"class":64},"Michael G. DeGroote Institute for Pain Research and Care (IPRC)","UNKNOWN","100592001","reducing-pain-in-complex-regional-pain-syndrome-using-personalized-brain-stimulation-a-feasibility-study-100592001",false,"NCT06987747","Reducing Pain in Complex Regional Pain Syndrome Using Personalized Brain Stimulation: A Feasibility Study","Reducing Pain in CRPS Using Personalized Brain Stimulation: A Feasibility Study","Inclusion Criteria:\n\n* Diagnosis of CRPS Type 1 affecting the upper or lower limb using the revised Budapest criteria\n* History of CRPS of at least 3 months since the start of symptoms or diagnosis\n\nExclusion Criteria:\n\n* CRPS diagnosis greater than 3 years to avoid patients with chronic CRPS who may not respond to interventions\n* Contraindications to transcranial magnetic stimulation (TMS)\n* Known psychological diagnosis affecting comprehension\n* Prior experience with TMS\n* Inability to participate in the study","ALL","18 Years","70 Years",{"count":76,"type":77},10,"ESTIMATED","INTERVENTIONAL",[80],"NA","This research study looks at the feasibility of using a new treatment, noninvasively activating the brain through repetitive transcranial magnetic stimulation (rTMS) to treat pain symptoms of complex regional pain syndrome (CRPS). This study will help us determine if this technique is feasible (able to recruit participants and if the research activities are feasible and can be used to treat CRPS patients with pain in a larger study. The investigators will also examine how TMS can be personalized to individuals using an individual's brain activity measured using EEG. The investigators will also study whether the effects of TMS are stronger if the TMS is delivered during a specific timing of the EEG activity.",[83],"Complex Regional Pain Syndrome (CRPS)",[85,86,87,88,89,90],"repetitive transcranial magnetic stimulation","personalized repetitive transcranial magnetic stimulation","Complex Regional Pain Syndrome","CRPS","Electroencephalogram","EEG guided TMS","NOT_YET_RECRUITING","2025-05-22",{"date":94,"type":95},"2025-05-23","ACTUAL",{"date":97,"type":77},"2025-07-01",{"date":99,"type":77},"2026-02-01",{"name":5,"class":6},1]