[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583600":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":12,"locations":7,"responsibleParty":18,"collaborators":20,"id":24,"slug":25,"hasResults":26,"nctId":27,"briefTitle":28,"officialTitle":29,"acronym":30,"eligibilityCriteria":31,"healthyVolunteers":26,"sex":32,"minAge":33,"maxAge":7,"enrollmentInfo":34,"targetDuration":7,"studyType":37,"phases":7,"briefSummary":38,"conditions":39,"keywords":41,"overallStatus":43,"whyStopped":7,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":7},{"fullName":5,"class":6},"University of Edinburgh","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"Functional and Cognitive scores","We will collect information about prior neurological symptoms, including prior symptoms suggestive of TIA or stroke, cognitive or motor symptoms, blood pressure and other known vascular risk factors, medicines, frailty, functional status, education, and employment status We will collect a baseline validated function and cognitive score, and take a sample of speech. Speech will be measured at assessment, in collaboration with the NeuroCARE Clinical and Digital Measures Module (22\u002FSS\u002F0010 IRAS No. 310885).",[13],{"name":14,"role":15,"phone":16,"phoneExt":7,"email":17},"William Whiteley","CONTACT","+44(131) 4659602","william.whiteley@ed.ac.uk",{"type":19,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[21],{"name":22,"class":23},"NHS Lothian","OTHER_GOV","100583600","reducing-risk-of-stroke-and-dementia-in-patients-with-covert-cerebrovascular-disease-100583600",false,"NCT06878430","Reducing Risk of Stroke and DementIa In patientS With COVert cERebrovascular Disease","Reducing Risk of Stroke and DementIa In patientS With COVert cERebrovascular Disease: a Pilot and Development Study","DISCOVER","Inclusion Criteria:\n\n* People who, at the time the letter is prepared or are identified by a clinician\n\n  * Age ≥ 65 years\n  * Have no known history of:\n\n    * Stroke or TIA\n    * Dementia\n    * Parkinson's disease\n    * Multiple sclerosis\n    * Metastatic cancer (or non-meningioma brain tumour).\n  * A CT or MRI scan report ≤5 years before study start date with of one or more of:\n\n    * Cerebral small vessel disease\n    * Deep old ischaemic stroke\n    * Cortical old ischaemic stroke\n\nExclusion Criteria:\n\n* Text of brain scan report unreadable\n* Do not consent to take part in study procedures\n* Unable to consent\n* Unable to communicate by email, letter or telephone through language, speech disability or lack of address\n* Unlikely to survive one year past enrolment in judgement of the study investigator","ALL","65 Years",{"count":35,"type":36},100,"ESTIMATED","OBSERVATIONAL","The purpose of the DISCOVER study is to pilot acceptable approaches to people with covert cerebrovascular disease (CCD) and their follow-up. This is the first step in designing efficient randomised trials of treatments to reduce the risk of stroke or dementia in people with CCD.",[40],"Covert Cerebrovascular Disease",[42],"ccd","NOT_YET_RECRUITING","2026-06-12",{"date":46,"type":47},"2026-06-16","ACTUAL",{"date":49,"type":36},"2026-08",{"date":51,"type":36},"2027-06",{"name":5,"class":6}]