[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100420446":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":19,"locations":27,"responsibleParty":46,"collaborators":7,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":7,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":7,"enrollmentInfo":58,"targetDuration":7,"studyType":61,"phases":7,"briefSummary":62,"conditions":63,"keywords":7,"overallStatus":30,"whyStopped":7,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"Charite University, Berlin, Germany","OTHER",null,[9,13,15,17],{"name":10,"affiliation":11,"role":12},"Martin Russ, Dr. med.","Charite University Hospital Berlin","PRINCIPAL_INVESTIGATOR",{"name":14,"affiliation":11,"role":12},"Philipp A Pickerodt, Dr. med.",{"name":16,"affiliation":11,"role":12},"Vladimir Skrypnikov, Dr. med.",{"name":18,"affiliation":11,"role":12},"Steffen Weber-Carstens, Prof. Dr. med.",[20,24],{"name":18,"role":21,"phone":22,"phoneExt":7,"email":23},"CONTACT","0049-30450651005","steffen.weber-carstens@charite.de",{"name":10,"role":21,"phone":25,"phoneExt":7,"email":26},"0049-30450651268","martin.russ@charite.de",[28],{"facility":29,"status":30,"city":31,"state":7,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Charité - Universitätsmedizin Berlin, Campus Virchow Klinikum","RECRUITING","Berlin","13353","Germany","DE",{"type":36,"coordinates":37},"Point",[38,39],13.41053,52.52437,{"lat":39,"lon":38},[42,45],{"name":18,"role":21,"phone":43,"phoneExt":7,"email":44},"0049-30450651055","steffen.webercarstens@charite.de",{"name":10,"role":21,"phone":25,"phoneExt":7,"email":26},{"type":12,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Steffen Weber-Carstens","Prof. Dr. med.","100420446","reduction-of-blood-recirculation-in-veno-venous-ecmo-100420446",false,"NCT04754854","Reduction of Blood Recirculation in Veno-Venous ECMO","Reduction of Blood Recirculation in Veno-Venous ECMO Through Ultrasound Dilution Measurements (ECMO Circulation Study)","Patients aged 18 years or older requiring veno-venous ECMO for treatment of refractory hypoxemia in ARDS.","ALL","18 Years",{"count":59,"type":60},136,"ESTIMATED","OBSERVATIONAL","Blood which recirculates through the circuit of a veno-venous Extracorporeal Membrane Oxygenation (V-V ECMO) does not contribute to the systemic oxygenation of a patient on V-V ECMO and is called the recirculation fraction (Rf). Theoretically, the optimization of ECMO blood flow is possible using Rf measurements.\n\nA prospective, observational study will be performed measuring the Rf of total ECMO blood flow in patients with acute respiratory distress syndrome (ARDS) on V-V ECMO with an ultrasound dilution technique.\n\nECMO blood flow will be optimized by reducing ECMO blood flow in accordance with the measured Rf as long as systemic oxygenation is not compromised.",[64,65],"Extracorporeal Membrane Oxygenation","Acute Respiratory Distress Syndrome","2024-12-28",{"date":68,"type":69},"2024-12-31","ACTUAL",{"date":71,"type":69},"2020-11-20",{"date":73,"type":60},"2026-10-31",{"name":5,"class":6},1]