[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100479744":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":41,"responsibleParty":62,"collaborators":66,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":73,"sex":79,"minAge":80,"maxAge":19,"enrollmentInfo":81,"targetDuration":19,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":44,"whyStopped":19,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Martin-Luther-Universität Halle-Wittenberg","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention Group","EXPERIMENTAL","Medication review (STOPP\u002FSTART-criteria) + telephone-based adherence support measure (motivational interviewing)",[13,14],"Other: Medication plan review","Behavioral: Adherence support",{"label":16,"type":17,"description":18,"interventionNames":19},"Control Group","NO_INTERVENTION","Usual care",null,[21,25],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":19},"Medication plan review","Intervention group patients will receive a revised medication plan by external pharmacologist based on the the STOPP\u002FSTART criteria. The revised medication plan will be provided to the family physician who then will provide it to the patient. The revision comes along with evidence based information for the physician to prevent possible uncertainties by the physicians.",[9],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":19},"BEHAVIORAL","Adherence support","Intervention group patients will receive a study nurse administered adherence support measure based on telephone-based motivational interviewing. The measure includes information on possible consequences of inadherence and signs of adverse drug reactions that is comprehensible for lay persons.",[9],[31],{"name":32,"affiliation":33,"role":34},"Thomas Frese, Prof.","MLU Halle-Wittenberg","STUDY_CHAIR",[36],{"name":37,"role":38,"phone":39,"phoneExt":19,"email":40},"Alexander Bauer, Dr.","CONTACT","+493455575338","raphael@uk-halle.de",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"HAP ANZ","RECRUITING","Halle","Saxony-Anhalt","06110","Germany","DE",{"type":51,"coordinates":52},"Point",[53,54],11.97947,51.48158,{"lat":54,"lon":53},[57,60],{"name":58,"role":38,"phone":59,"phoneExt":19,"email":19},"Hildegard Anz, MD","+49 345 6783847",{"name":58,"role":61,"phone":19,"phoneExt":19,"email":19},"SUB_INVESTIGATOR",{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"PRINCIPAL_INVESTIGATOR","Alexander Bauer","Reserach Coordinator",[67,69],{"name":68,"class":6},"University of Leipzig",{"name":70,"class":6},"Hannover Medical School","100479744","reduction-of-polypharmacy-in-elderly-people-with-multiple-diseases-100479744",false,"NCT05526963","Reduction of Polypharmacy in Elderly People With Multiple Diseases","Reduction of Polypharmacy in Elderly People With Multiple Diseases - a Stepped Wedge Cluster-randomized Controlled Trial","RED","Inclusion Criteria:\n\n* ≥ 5 longterm medications (\\> 6 months) (polypharmacy)\n* ≥ 3 chronic diseases (multimorbidity)\n* ≥ 1 family doctor consultation within the last 6 months\n\nExclusion Criteria:\n\n* Patients with a critically reduced life expectancy\n* Patients who cannot autonomously visit the family practice\n* Patients who cannot participate in the informed consent process\n* Patients who are residing in a nursing home\n* Patients with dementia or a mental of behavioral disorder ICD-10 F00-F99\n* Patients who are participating in another medical study with a focus on polypharmacy or multimorbidity","ALL","70 Years",{"count":82,"type":83},1146,"ESTIMATED","INTERVENTIONAL",[86],"NA","Elderly GP patients are often treated with five or more medications and therefore prone to adverse drug reactions (ADR). Potentially inappropriate prescriptions (PIPs) lead to increased adverse events like falls, hospitalizations and mortality. The primary aim of this study to reduce the frequency of ADRs in multimorbid patients aged 70 years and older by reducing polypharmacy.",[89,90],"Polypharmacy","Multimorbidity",[92,89,90,93],"Primary Care","Drug-Related Side Effects and Adverse Reactions","2025-01-07",{"date":96,"type":97},"2025-01-09","ACTUAL",{"date":99,"type":97},"2024-05-30",{"date":101,"type":83},"2025-12-31",{"name":5,"class":6},1]