[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100437935":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":16,"locations":25,"responsibleParty":51,"collaborators":10,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":56,"sex":62,"minAge":10,"maxAge":10,"enrollmentInfo":63,"targetDuration":66,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":72,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Istituto Ortopedico Rizzoli","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Patients affected by Li Fraumeni and Li Fraumeni Like syndromes",null,"The group comprises all patients affected by Li Fraumeni and Li Fraumeni Like syndromes",[13],{"name":14,"affiliation":5,"role":15},"Luca Sangiorgi, MSc","PRINCIPAL_INVESTIGATOR",[17,22],{"name":18,"role":19,"phone":20,"phoneExt":10,"email":21},"Marina Mordenti, PhD","CONTACT","+39-0516366062","registri.malattierare@ior.it",{"name":23,"role":19,"phone":24,"phoneExt":10,"email":21},"Marcella Lanza, PhD","+39-0516366169",[26,45],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Irccs Istituto Ortopedico Rizzoli","RECRUITING","Bologna","Emilia-Romagna","40136","Italy","IT",{"type":35,"coordinates":36},"Point",[37,38],11.33875,44.49381,{"lat":38,"lon":37},[41,43],{"name":18,"role":19,"phone":42,"phoneExt":10,"email":21},"+39 051 6366062",{"name":23,"role":19,"phone":44,"phoneExt":10,"email":21},"+39 051 6366169",{"facility":46,"status":47,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":48,"geoPoint":50,"contacts":10},"IRCCS Istituto Ortopedico Rizzoli","ENROLLING_BY_INVITATION",{"type":35,"coordinates":49},[37,38],{"lat":38,"lon":37},{"type":15,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Luca Sangiorgi","Head of Department of Rare Skeletal Disorders","100437935","registry-of-li-fraumeni-and-li-fraumeni-like-syndromes-100437935",false,"NCT04982744","Registry of Li Fraumeni and Li Fraumeni Like Syndromes","Registry of Li Fraumeni and Li Fraumeni Like Syndromes That Collects Clinical, Functional, Genetic, Genealogical, Imaging, Surgical, Treatment, Quality of Life Data. Data is Linked to Patients' Biological Samples, When Available","ReLF","Inclusion Criteria:\n\n* All patients affected by Li Fraumeni or Li Fraumeni Like syndromes\n\nExclusion Criteria:\n\n* Any condition unrelated to Li Fraumeni or Li Fraumeni Like syndromes","ALL",{"count":64,"type":65},200,"ESTIMATED","10 Years","OBSERVATIONAL","ReLF is a retrospective and prospective registry, finalized for care and research purposes. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains: personal information, clinical data, genetic data, genealogical data, surgeries, etc. This approach has been developed to corroborate and integrate data from different resources and aspects of the diseases and to correlate genetic background and phenotypic outcomes, in order to better investigate diseases pathophysiology. Due to legal requirements, institutional directives and organizational issues, we are unable to include individuals residing outside Italy in the registry at this time. We are currently engaged in the preparation of a recruitment process for individuals residing outside Italy.",[70,71],"Li-Fraumeni Syndrome","Li-Fraumeni-Like Syndrome",[73,74,75,76],"Disease Registry","Natural History Study","Genotype-Phenotype Correlation","Disease Evolution","2025-11-17",{"date":79,"type":80},"2025-11-20","ACTUAL",{"date":82,"type":80},"2020-07-02",{"date":84,"type":65},"2045-07",{"name":5,"class":6},2]