[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100369811":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":10,"centralContacts":40,"locations":50,"responsibleParty":131,"collaborators":10,"id":133,"slug":134,"hasResults":135,"nctId":136,"briefTitle":137,"officialTitle":138,"acronym":139,"eligibilityCriteria":140,"healthyVolunteers":135,"sex":141,"minAge":142,"maxAge":143,"enrollmentInfo":144,"targetDuration":10,"studyType":147,"phases":10,"briefSummary":148,"conditions":149,"keywords":157,"overallStatus":53,"whyStopped":10,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":165,"completionDateStruct":167,"leadSponsor":169,"locationsCount":170},{"fullName":5,"class":6},"Associazione Italiana per lo Studio del Pancreas","OTHER",[8,14,17,21,24,27],{"label":9,"type":10,"description":10,"interventionNames":11},"Familial pancreatic cancer relatives",null,[12,13],"Radiation: MRCP","Procedure: Endoultrasonography",{"label":15,"type":10,"description":10,"interventionNames":16},"Peutz-Jeghers syndrome",[12,13],{"label":18,"type":10,"description":19,"interventionNames":20},"BRCA 1\u002F2, PALB2, p16 mutations with familiarity for PC","Known genetic mutation and at least 1 1st- or 2nd-degree relative suffering from PC",[12,13],{"label":22,"type":10,"description":10,"interventionNames":23},"Lynch syndrome with familiarity for pancreatic cancer",[12,13],{"label":25,"type":10,"description":10,"interventionNames":26},"FAMMM syndrome",[12,13],{"label":28,"type":10,"description":10,"interventionNames":29},"Hereditary and genetic pancreatitis",[12,13],[31,36],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":10},"RADIATION","MRCP","Subjects fulfilling the \"radiological follow-up criteria\" will be submitted to MRCP or EUS according to the pancreatologist's prescription",[18,25,9,28,22,15],{"type":37,"name":38,"description":34,"armGroupLabels":39,"otherNames":10},"PROCEDURE","Endoultrasonography",[18,25,9,28,22,15],[41,46],{"name":42,"role":43,"phone":44,"phoneExt":10,"email":45},"Salvatore Paiella, MD, PhD","CONTACT","00390458126009","salvatore.paiella@univr.it",{"name":47,"role":43,"phone":48,"phoneExt":10,"email":49},"Silvia Carrara, MD","+ 39 02 82247288","silvia.carrara@humanitas.it",[51,76,92,107],{"facility":52,"status":53,"city":54,"state":55,"zip":10,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"Istituto Clinico Humanitas","RECRUITING","Rozzano","Milan","Italy","IT",{"type":59,"coordinates":60},"Point",[61,62],9.1559,45.38193,{"lat":62,"lon":61},[65,66,69,71,74],{"name":47,"role":43,"phone":10,"phoneExt":10,"email":49},{"name":67,"role":68,"phone":10,"phoneExt":10,"email":10},"Alessandro Zerbi, MD","PRINCIPAL_INVESTIGATOR",{"name":70,"role":68,"phone":10,"phoneExt":10,"email":10},"Luigi Laghi, MD, PhD",{"name":72,"role":73,"phone":10,"phoneExt":10,"email":10},"Laura Poliani, MD","SUB_INVESTIGATOR",{"name":75,"role":73,"phone":10,"phoneExt":10,"email":10},"Valentina Giatti",{"facility":77,"status":53,"city":78,"state":79,"zip":10,"country":56,"countryCode":57,"cosmosGeoPoint":80,"geoPoint":84,"contacts":85},"Ospedale Pederzoli","Peschiera del Garda","Verona",{"type":59,"coordinates":81},[82,83],10.68614,45.43912,{"lat":83,"lon":82},[86,88,90],{"name":87,"role":43,"phone":10,"phoneExt":10,"email":10},"Giovanni Butturini, MD",{"name":89,"role":73,"phone":10,"phoneExt":10,"email":10},"Alessandro Giardino, MD, PhD",{"name":91,"role":73,"phone":10,"phoneExt":10,"email":10},"Isabella Frigerio, MD, PhD",{"facility":93,"status":53,"city":55,"state":10,"zip":10,"country":56,"countryCode":57,"cosmosGeoPoint":94,"geoPoint":98,"contacts":99},"San Raffele Vita Salute University Hospital",{"type":59,"coordinates":95},[96,97],12.59836,42.78235,{"lat":97,"lon":96},[100,103,105],{"name":101,"role":43,"phone":10,"phoneExt":10,"email":102},"Massimo Falconi, MD","massimo.falconi@hsr.it",{"name":104,"role":68,"phone":10,"phoneExt":10,"email":10},"Gabriele Capurso, MD, PhD",{"name":106,"role":73,"phone":10,"phoneExt":10,"email":10},"Silvia Smaniotto",{"facility":108,"status":53,"city":79,"state":10,"zip":109,"country":56,"countryCode":57,"cosmosGeoPoint":110,"geoPoint":114,"contacts":115},"Chirurgia Generale e del Pancreas","37134",{"type":59,"coordinates":111},[112,113],10.9938,45.43854,{"lat":113,"lon":112},[116,117,121,122,124,126,128,129],{"name":42,"role":43,"phone":44,"phoneExt":10,"email":45},{"name":118,"role":43,"phone":119,"phoneExt":10,"email":120},"Erica Secchettin, PharmD","00390458126254","erica.secchettin@univr.it",{"name":42,"role":68,"phone":10,"phoneExt":10,"email":10},{"name":123,"role":68,"phone":10,"phoneExt":10,"email":10},"Giuseppe Malleo, MD, PhD",{"name":125,"role":68,"phone":10,"phoneExt":10,"email":10},"Claudio Bassi, MD",{"name":127,"role":68,"phone":10,"phoneExt":10,"email":10},"Roberto Salvia, MD, PhD",{"name":118,"role":73,"phone":10,"phoneExt":10,"email":10},{"name":130,"role":73,"phone":10,"phoneExt":10,"email":10},"Veronica Marinelli, PhD",{"type":132,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100369811","registry-of-subjects-at-risk-of-pancreatic-cancer-100369811",false,"NCT04095195","Registry of Subjects at Risk of Pancreatic Cancer","Italian Registry of Families At Risk of Pancreatic Cancer","IRFARPC","Inclusion Criteria to enter the registry:\n\n* individuals with at least two relatives suffering from pancreatic cancer, with at least 1 first-degree and until the third-degree\n* subjects with known genetic mutation of BRCA2, BRCA1, p16, PALB2 with at least 1 first- or 2nd-degree relative suffering from pancreatic cancer\n* subjects suffering from FAMMM Syndrome\n* subjects suffering from Peutz-Jeghers Syndrome\n* subjects suffering from PRSS-1- or CFTR- or SPINK-1- related pancreatitis\n* subjects suffering from Lynch syndrome with at least 1 first- or 2nd-degree relative suffering from pancreatic cancer\n\nInclusion criteria to join the \"radiologic follow-up\":\n\n* 45 years or 10 years younger than the youngest index case of pancreatic cancer in the family for familial cases\n* 40 years or 5 years younger than the youngest index case of pancreatic cancer for subjects suffering from hereditary\u002Fgenetic pancreatitis, Lynch syndrome, or carrying a known BRCA 1\u002F2, PALB2, p16 genetic mutation with familiarity for pancreatic cancer\n* 30 years for subjects suffering from FAMMM, Peutz-Jeghers syndrome\n\nExclusion Criteria:\n\n\\- pregnancy","ALL","18 Years","80 Years",{"count":145,"type":146},1000,"ESTIMATED","OBSERVATIONAL","IRFARPC is a multicenter national registry designed to study the diagnosis and predisposing factors of subjects with an inherited increased risk for pancreatic cancer.",[150,151,152,153,154,155,156],"Familial Pancreatic Cancer","BRCA1 Mutation","BRCA2 Mutation","Lynch Syndrome","FAMMM - Familial Atypical Mole Malignant Melanoma Syndrome","Hereditary Pancreatitis","Peutz-Jeghers Syndrome",[150,158,153,159,160],"BRCA Mutation","Screening pancreatic cancer","Surveillance pancreatic cancer","2023-01-12",{"date":163,"type":164},"2023-01-13","ACTUAL",{"date":166,"type":164},"2019-08-20",{"date":168,"type":146},"2045-09-20",{"name":5,"class":6},4]