[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627482":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":33,"responsibleParty":116,"collaborators":10,"id":118,"slug":119,"hasResults":120,"nctId":121,"briefTitle":122,"officialTitle":123,"acronym":10,"eligibilityCriteria":124,"healthyVolunteers":120,"sex":125,"minAge":126,"maxAge":10,"enrollmentInfo":127,"targetDuration":130,"studyType":131,"phases":10,"briefSummary":132,"conditions":133,"keywords":136,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":141,"lastUpdatePostDateStruct":142,"startDateStruct":145,"completionDateStruct":147,"leadSponsor":149,"locationsCount":150},{"fullName":5,"class":6},"Memorial Sloan Kettering Cancer Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Participants Who Are Having an Esophagectomy and Are at High Risk of Anastomotic Leak",null,"Participants who are undergoing preoperative gastric preconditioning by percutaneous angioembolization before esophagectomy for esophageal malignancy and who have a high risk of anastomotic leak",[13],"Procedure: Esophagectomy",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"PROCEDURE","Esophagectomy","Eligible participants will undergo esophagectomy after preoperative gastric preconditioning by percutaneous angioembolization.",[9],[21],{"name":22,"affiliation":5,"role":23},"Daniela Molena, MD","PRINCIPAL_INVESTIGATOR",[25,29],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":28},"CONTACT","212-639-3870","molenad@mskcc.org",{"name":30,"role":26,"phone":31,"phoneExt":10,"email":32},"Ernesto Santos Martin, MD","212-639-7327","santosme@mskcc.org",[34,50,61,72,84,95,105],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Memorial Sloan Kettering Basking Ridge (All Protocol Activities)","RECRUITING","Basking Ridge","New Jersey","07920","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-74.54932,40.70621,{"lat":46,"lon":45},[49],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":10},{"facility":51,"status":36,"city":52,"state":38,"zip":53,"country":40,"countryCode":41,"cosmosGeoPoint":54,"geoPoint":58,"contacts":59},"Memorial Sloan Kettering Monmouth (All Protocol Activities)","Middletown","07748",{"type":43,"coordinates":55},[56,57],-74.11709,40.39428,{"lat":57,"lon":56},[60],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":10},{"facility":62,"status":36,"city":63,"state":38,"zip":64,"country":40,"countryCode":41,"cosmosGeoPoint":65,"geoPoint":69,"contacts":70},"Memorial Sloan Kettering Bergen (All Protocol Activities)","Montvale","07645",{"type":43,"coordinates":66},[67,68],-74.02292,41.04676,{"lat":68,"lon":67},[71],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":10},{"facility":73,"status":36,"city":74,"state":75,"zip":76,"country":40,"countryCode":41,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"Memorial Sloan Kettering Suffolk - Commack (All Protocol Activities)","Commack","New York","11725",{"type":43,"coordinates":78},[79,80],-73.29289,40.84288,{"lat":80,"lon":79},[83],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":10},{"facility":85,"status":36,"city":86,"state":75,"zip":87,"country":40,"countryCode":41,"cosmosGeoPoint":88,"geoPoint":92,"contacts":93},"Memorial Sloan Kettering Westchester (All protocol activities)","Harrison","10604",{"type":43,"coordinates":89},[90,91],-73.71263,40.96899,{"lat":91,"lon":90},[94],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":10},{"facility":96,"status":36,"city":75,"state":75,"zip":97,"country":40,"countryCode":41,"cosmosGeoPoint":98,"geoPoint":102,"contacts":103},"Memorial Sloan Kettering Cancer Center (All Protocol Activities)","10065",{"type":43,"coordinates":99},[100,101],-74.00597,40.71427,{"lat":101,"lon":100},[104],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":10},{"facility":106,"status":36,"city":107,"state":75,"zip":108,"country":40,"countryCode":41,"cosmosGeoPoint":109,"geoPoint":113,"contacts":114},"Memorial Sloan Kettering Nassau (All Protocol Activities)","Rockville Centre","11553",{"type":43,"coordinates":110},[111,112],-73.64124,40.65871,{"lat":112,"lon":111},[115],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":10},{"type":117,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100627482","registry-study-of-people-who-are-having-an-esophagectomy-and-are-at-high-risk-of-anastomotic-leak-100627482",false,"NCT07449208","Registry Study of People Who Are Having an Esophagectomy and Are at High Risk of Anastomotic Leak","Gastric Preconditioning by Percutaneous Angioembolization Before Esophagectomy in Patients With a High Risk of Anastomotic Leak","Inclusion Criteria:\n\n* Documentation of Disease\n\n  * Patients must have pathologically confirmed esophageal malignancy requiring esophagectomy.\n  * Patients must also have risk factors for anastomotic leak:\n  * Previous foregut or bariatric surgery (gastric sleeve or gastric bypass), but excluding fundoplication-only surgery OR\n  * Salvage esophagectomy OR\n  * Planned cervical anastomosis OR\n  * Two or more comorbidities:\n  * Diabetes, obesity, coronary artery disease, vascular disease (including celiac stricture or atherosclerosis, significant aortic disease, or any previous diagnosis of peripheral arterial disease), steroid use, hypertension, current or former smoker, renal insufficiency, and heart failure.\n* Definition of Disease\n\n  * Patients must have pathologically confirmed esophageal malignancy requiring esophagectomy and risk factors for anastomotic leak, as described above.\n  * Patients must be candidate and have agreed to receive gastric preconditioning procedure\n* Prior Treatment\n\n  o There are no requirements with regard to prior treatment.\n* Age ≥ 18\n* ECOG Performance Status of ≤ 2 (See Appendix I for performance status criteria)","ALL","18 Years",{"count":128,"type":129},40,"ESTIMATED","1 Year","OBSERVATIONAL","The main purpose of this study is to look at how often anastomotic leaks happen in participants who are at high risk of these leaks and are eligible to receive gastric preconditioning by percutaneous angioembolization before an esophagectomy.",[134,135],"Esophageal Malignant Neoplasm Primary","Anastomotic Leak",[137,138,139,5,140],"esophageal malignancy","esophagectomy","anastomotic leak","26-045","2026-02-27",{"date":143,"type":144},"2026-03-04","ACTUAL",{"date":146,"type":144},"2026-02-25",{"date":148,"type":129},"2029-02-25",{"name":5,"class":6},7]