[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100580526":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":38,"collaborators":10,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":43,"sex":49,"minAge":50,"maxAge":10,"enrollmentInfo":51,"targetDuration":54,"studyType":55,"phases":10,"briefSummary":56,"conditions":57,"keywords":10,"overallStatus":20,"whyStopped":10,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":68},{"fullName":5,"class":6},"Seoul National University Bundang Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"NTM-PD Pulmonary Rehabilitation Cohort",null,"This cohort consists of adults diagnosed with nontuberculous mycobacterial pulmonary disease (NTM-PD) who will undergo pulmonary rehabilitation and airway clearance training as part of a prospective observational study. Participants will receive an 8-week biweekly pulmonary rehabilitation program, including oscillating positive expiratory pressure (OPEP) therapy, high-frequency chest wall oscillation (HFCWO), huffing and coughing techniques, breathing exercises, and aerobic\u002Fstrength training. They will be monitored at baseline, during treatment, and at 2-month and 6-month follow-ups, undergoing pulmonary function tests (PFT), bacteriologic assessments, radiographic imaging (CT\u002FX-ray), symptom evaluations, and quality of life assessments (EQ-5D-5L, CAT score). This study aims to assess the effectiveness of non-pharmacological interventions in improving respiratory function, reducing symptoms, and enhancing quality of life in NTM-PD patients.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Hyung-Jun Kim, MD","CONTACT","+82-31-787-7844","dr.hjkim@snu.ac.kr",[19],{"facility":5,"status":20,"city":21,"state":22,"zip":23,"country":24,"countryCode":10,"cosmosGeoPoint":25,"geoPoint":30,"contacts":31},"RECRUITING","Seongnam-si","Gyeonggi-do","13620","South Korea",{"type":26,"coordinates":27},"Point",[28,29],127.13778,37.43861,{"lat":29,"lon":28},[32,33,35],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},{"name":14,"role":34,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"name":36,"role":37,"phone":10,"phoneExt":10,"email":10},"Jaewon Beom, MD","SUB_INVESTIGATOR",{"type":34,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Hyung-Jun Kim","Professor","100580526","rehabilitation-exercise-and-education-of-airway-clearance-technique-in-ntm-pd-a-prospective-cohort-study-100580526",false,"NCT06838442","Rehabilitation Exercise and Education of Airway Clearance Technique in NTM-PD: A Prospective Cohort Study","Rehabilitation Exercise and Education of Airway Clearance Technique in Nontuberculous Mycobacterial Pulmonary Disease: A Prospective Cohort Study","NTM-Rehab","Inclusion Criteria:\n\n* Age 20 years or older at the time of enrollment.\n* Diagnosis of nontuberculous mycobacterial pulmonary disease (NTM-PD) according to the 2020 American Thoracic Society (ATS) guidelines.\n* Identification of clinically significant NTM species, including:\n\nMycobacterium avium \u002F Mycobacterium intracellulare \u002F Mycobacterium abscessus \u002F Mycobacterium massiliense \u002F Mycobacterium kansasii \u002F\n\n* Able to undergo pulmonary rehabilitation and airway clearance training as part of the study protocol.\n* Willing to provide written informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Currently pregnant or actively breastfeeding.\n* Unable to participate in pulmonary rehabilitation due to severe mobility impairment or neuromuscular disorders.\n* History of massive hemoptysis or other medical conditions where airway clearance techniques may be contraindicated.","ALL","20 Years",{"count":52,"type":53},500,"ESTIMATED","6 Months","OBSERVATIONAL","* The goal of this observational study is to evaluate the effects of pulmonary rehabilitation and airway clearance education in adults with nontuberculous mycobacterial pulmonary disease (NTM-PD). The main questions it aims to answer are:\n\n  * Does pulmonary rehabilitation and airway clearance training improve lung function, symptom relief, and quality of life in patients with NTM-PD?\n  * Does this non-pharmacological intervention contribute to better sputum culture conversion rates?\n* Participants will:\n\n  * Undergo pulmonary rehabilitation and airway clearance training over an 8-week period (biweekly sessions).\n  * Receive evaluations at baseline, during the intervention, and follow-up assessments at 2 months, 6 months, and final study visit.\n  * Undergo tests including pulmonary function tests (PFT), symptom assessments, bacteriologic evaluations, radiographic imaging (CT\u002FX-ray), and quality of life surveys (EQ-5D-5L, CAT score).\n* This study aims to provide clinical evidence supporting the role of non-pharmacological treatments in the management of NTM-PD, potentially informing future treatment guidelines and improving patient outcomes.",[58],"Nontuberculous Mycobacterial Pulmonary Disease","2025-06-25",{"date":61,"type":62},"2025-06-29","ACTUAL",{"date":64,"type":62},"2025-04-21",{"date":66,"type":53},"2028-11-25",{"name":5,"class":6},1]