[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100499572":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":44,"responsibleParty":65,"collaborators":68,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":78,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":25,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":47,"whyStopped":25,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Rigshospitalet, Denmark","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Aerobe graded physical exercise intervention and usual care","EXPERIMENTAL","Physical exercise program. The experimental programme is an add-on to usual care and consists of an aerobe graded exercise program performed twice a week for 12 weeks. Usual care includes all public treatments that each patient is assigned to at entry to REPCon. The provision of officially available treatments follow the Danish Health Care Act.",[13],"Other: Physical exercise programme as an add-on",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual care","PLACEBO_COMPARATOR","No physical exercise program in a patient control group with PCS. This group continues with usual care, but all clinical test, interviews and MRI protocol are the same.",[19],"Other: Control patients receiving usual care",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Physical exercise programme as an add-on","Consists of an individually tailored bike exercise program guided by symptoms, pulse rate and patient specific judgement of exertion monitored also by BORG RPE and VAS and progressively increasing time and level of resistance below symptom provocation",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Control patients receiving usual care","No exercise intervention",[15],[31],{"name":32,"affiliation":33,"role":34},"Henrik BW Larsson, Professor","Faculty of Health and Medical Science, University of Copenhagen, Denmark","PRINCIPAL_INVESTIGATOR",[36,40],{"name":32,"role":37,"phone":38,"phoneExt":25,"email":39},"CONTACT","(+45) 24824294","henrik.bo.wiberg.larsson@regionh.dk",{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},"Mette K Zebis, PhD","(+45) 30291943","mzeb@kp.dk",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"University College Copenhagen","RECRUITING","Copenhagen","Region of Greater Copenhagen","1799","Denmark","DK",{"type":54,"coordinates":55},"Point",[56,57],12.56553,55.67594,{"lat":57,"lon":56},[60,63],{"name":61,"role":37,"phone":62,"phoneExt":25,"email":43},"Mette K Zebis, Affiliate Professor","+45 51632437",{"name":32,"role":37,"phone":64,"phoneExt":25,"email":39},"+45 38632432",{"type":34,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Henrik Bo Wiberg Larsson","Consultant, professor",[69],{"name":46,"class":6},"100499572","rehabilitation-in-post-concussion-syndrome-100499572",false,"NCT05785000","Rehabilitation in Post Concussion Syndrome","Rehabilitation of Adult Patients With Post Concussion Syndrome","REPCon","Inclusion Criteria:\n\n* Post concussion syndrome (PCS) diagnose according to WHO ICD-10 classification and documented by written statement from physician veritying a mild traumatic brain injury\n* Longer lasting symptoms for at least 4 weeks after initial trauma\n* If allocated to add-on exercise protocol participant must feel able to prioritize the intervention structure\n* Communication language must be Danish\n\nExclusion Criteria:\n\n* Other diseases blurring the diagnose PCS\n* Other serious brain diseases\n* Severe cardiovascular diseases precluding physical activity according to protocol",true,"ALL","18 Years","70 Years",{"count":83,"type":84},70,"ESTIMATED","INTERVENTIONAL",[87],"NA","This project evaluates and quantifies the effects of an individually tailored exercise program applied to patients with long-lasting symptoms after concussion, minor traumatic brain injury, so-called Post-Concussion Syndrome (PCS). The project investigates the phenomenon Post Concussion Syndrome in four dimensions with a focus on both patient perspectives of PCS, an interventional physical program, a neurobiological basis for PCS through Magnetic Resonance Imaging (MRI) and finally through a 360-degree evaluation of the entire project involving patients and scientists in a reflective process.",[90],"Post-Concussion Syndrome",[92,93,94,95,96,97],"Mild traumatic brain injury","Brain function","Magnetic Resonance Imaging","Buffalo Concussion Bike Test","Patient perception","360-degree evaluation","2026-01-20",{"date":100,"type":101},"2026-01-22","ACTUAL",{"date":103,"type":101},"2023-02-01",{"date":105,"type":84},"2026-04",{"name":5,"class":6},1]