[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100522995":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":24,"locations":35,"responsibleParty":78,"collaborators":18,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":82,"sex":88,"minAge":89,"maxAge":18,"enrollmentInfo":90,"targetDuration":18,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":101,"overallStatus":106,"whyStopped":18,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"Hospices Civils de Lyon","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"PAMPERO program group","EXPERIMENTAL","This program is an intensive multidisciplinary program rehabilitation including Physical, Occupational, Speech, Psychomotor therapy and Adapted Physical Activity.",[13],"Other: PAMPERO program",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual Care intervention group","NO_INTERVENTION","Usual Rehabilitation of the patient after the inclusion. 0 to 2 physical therapy sessions and 0 to 2 Speech therapy sessions each week usually constitute this program.\n\nThis rehabilitation highly depends on the patients usual preferences. Some patients have no rehabilitation in the daily care while some have more.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"PAMPERO program","This program is an intensive multidisciplinary program rehabilitation including Physical, Occupational, Speech, Psychomotor therapy and Adapted Physical Activity. The duration of this program is 5 weeks and each week is divided as follow :\n\n* 5 hours of physical therapy : individual session with the objective to improve the dynamic balance and coordination on the aim to gain confidence of moving, gripping capacity and interaction with object\n* 5 hours of Adapted Physical activity : group session to promote pairing with muscle building priority\n* 1 hour of Speech therapy : group session to educate and promote prevention strategy about dysphagia rick\n* 2 hours of Occupational therapy : group session to bring adaptive solution of autonomy lost with material propose, home organisation or gesture\n* 2 hours of Hydrotherapy : group session activity performed in water to assist rehabilitation",[9],[25,31],{"name":26,"role":27,"phone":28,"phoneExt":29,"email":30},"Lucas PIGNON","CONTACT","04 78 86 50 58","+33","lucas.pignon@chu-lyon.fr",{"name":32,"role":27,"phone":33,"phoneExt":29,"email":34},"Christelle MAROLHO","04 72 11 57 68","christelle.marolho@chu-lyon.fr",[36,53,67],{"facility":37,"status":18,"city":38,"state":18,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Service de Rééducation Fonctionnelle (S.S.R.) Val Rosay","Saint-Didier-au-Mont-d'Or","69370","France","FR",{"type":43,"coordinates":44},"Point",[45,46],4.7985,45.81068,{"lat":46,"lon":45},[49],{"name":50,"role":27,"phone":51,"phoneExt":29,"email":52},"Julie MD Di Marco","04 72 53 21 65","julie.dimarco@ugecam.assurance-maladie.fr",{"facility":54,"status":18,"city":55,"state":18,"zip":56,"country":40,"countryCode":41,"cosmosGeoPoint":57,"geoPoint":61,"contacts":62},"Service de Médecine Physique et Réadaptation (M.P.R) de l'Hôpital Bellevue","Saint-Etienne","42100",{"type":43,"coordinates":58},[59,60],4.39,45.43389,{"lat":60,"lon":59},[63],{"name":64,"role":27,"phone":65,"phoneExt":29,"email":66},"Pascal MD Giraux","04 77 12 77 57","pascal.giraux@univ-st-etienne.fr",{"facility":68,"status":18,"city":69,"state":18,"zip":70,"country":40,"countryCode":41,"cosmosGeoPoint":71,"geoPoint":75,"contacts":76},"Service de Rééducation Fonctionnelle (S.S.R.) de l'Hôpital Henry Gabrielle Hospices Civils de Lyon","Saint-Genis-Laval","69230",{"type":43,"coordinates":72},[73,74],4.79316,45.69542,{"lat":74,"lon":73},[77],{"name":26,"role":27,"phone":28,"phoneExt":29,"email":30},{"type":79,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100522995","rehabilitation-program-on-genetic-and-degenerative-ataxia-100522995",false,"NCT06089863","Rehabilitation Program on Genetic and Degenerative Ataxia","Evaluation of the Effect of PAMPERO Rehabilitation Program in Collaboration With Patient Partner on the Symptom Intensity, Activity, and Quality of Life on Genetic and Degenerative Ataxia","RAPP","Inclusion Criteria:\n\n* ≥ 18 years\n* Patients with genetic and degenerative cerebellar ataxia\n* Diagnostic of cerebellar ataxia confirmed by anatomic MRI\n* Affiliated to a social insurgence regime or similar\n* Patients who have given their free, informed and express consent\n* Walking patients (who can walk unsupervised on flat ground with the help of proper technique : categories greater than 4 on the New Functional Ambulation Classification scale)\n\nNon inclusion Criteria:\n\n* Patients who have already benefited from a hospitalization of more than 3 weeks for rehabilitation during the last 12 months\n* Patients participating simultaneously in another research whose objective would be the evaluation of a therapy, medicinal or not, likely to improve neurological or functional recovery\n* Pregnants, parturient or breastfeeding\n* Patients deprived of their liberty by a judicial or administrative decision\n* Psychiatric care patients\n* Patients admitted to Patients admitted to a health or social establishment for purposes other than research for purposes other than research\n* Major patients protected by the Law","ALL","18 Years",{"count":91,"type":92},48,"ESTIMATED","INTERVENTIONAL",[95],"NA","Cerebellar ataxia is a pathology linked to the lesion of the cerebellum or the afferent and\u002For efferent cerebellar pathways. The aetiology can be an acquired cerebral lesion, following a chemical poisoning or a genetic degenerative lesion (for example : Friedreich's ataxia, spinocerebellar ataxias, etc.). As reported by the latest estimate available, genetic degenerative cerebellar ataxias affect approximately 6,000 patients in France (Orpha.net). Symptoms suffered by ataxic patients are : problems and gait disorders along with difficulties in coordination resulting in ataxia, uncoordinated movements.\n\nThese symptoms cause a decrease in the quality of life on patients with spinocerebellar ataxia. The symptoms improvement linked to the cerebellar syndrome is based on rehabilitation that can be supplemented by use of technical aids. Current scientific knowledge confirms that intensive rehabilitation by physiotherapy and occupational therapy in patients with degenerative ataxias improves cerebellar symptoms. Nevertheless, the choice rehabilitation technique stay at the appreciation of the therapist.\n\nFrom the observation, the investigators have designed an intensive multidisciplinary rehabilitation program, called PAMPERO, with partner patients member of two genetic degenerative ataxia patient organisations. This 5-weeks program has been used in clinic during 3 years on 28 patients. It appears to be the only one in France.\n\nThe preliminary results show a positive effect on ataxia symptom. Nevertheless, the duration of the benefice over time and the effect on the quality of life stay unknown.\n\nHowever, the quality of life is mainly affected by the participation restriction due to the risk of falling. The most frequent complaint from partner patient is the diminution of the social interaction resulting of the incapacity to move without risk.\n\nThe present protocol aimed at evaluating the Rehabilitation Program in collaboration with partner patient on the symptom intensity, activity and quality of life on genetic and degenerative ataxia.\n\nThis PAMPERO program's effect will be assessed by comparing the difference of Intensity of symptom measured by to Scale for the Assessment and Rating of Ataxia (SARA) at inclusion and 3 months after the end of rehabilitation.",[98,99,100],"Ataxia","Degenerative Disease","Genetic Disease",[102,103,104,105],"Genetic ataxia","Degenerative ataxia","Rehabilitation","Cerebellar ataxia","NOT_YET_RECRUITING","2024-01-15",{"date":109,"type":110},"2024-01-17","ACTUAL",{"date":112,"type":92},"2024-02-01",{"date":114,"type":92},"2027-10-01",{"name":5,"class":6},3]