[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100610642":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":18,"centralContacts":22,"locations":28,"responsibleParty":47,"collaborators":51,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":10,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":68,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Istanbul University - Cerrahpasa","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Control group",null,"Inclusion Criteria\n\nBeing between 20 and 60 years of age, Having bilateral pure-tone audiometry averages (500-1000-2000-4000 Hz) within the normal range (≤25 dB HL), Having no tinnitus or auditory complaints, Scoring 21 or above on the MoCA test, Having no emotional or neurological problems that could interfere with the tests.\n\nExclusion Criteria\n\nPresence of peripheral and\u002For central hearing loss, Presence of somatosensory tinnitus, Presence of emotional and\u002For neurological problems that could interfere with the tests.",{"label":13,"type":10,"description":14,"interventionNames":10},"First study group","Inclusion Criteria\n\nBeing between 20 and 60 years of age, Having bilateral pure-tone audiometry averages (500-1000-2000-4000 Hz) within the normal range (≤25 dB HL), Having a chronic tinnitus complaint (≥3 months), Scoring 21 or above on the MoCA test, Having no emotional or neurological problems that could interfere with the tests.\n\nExclusion Criteria\n\nPresence of peripheral and\u002For central hearing loss, Presence of somatosensory tinnitus, Presence of emotional and\u002For neurological problems that could interfere with the tests.",{"label":16,"type":10,"description":17,"interventionNames":10},"Second study group","Inclusion Criteria\n\nBeing between 20 and 60 years of age, Having bilateral pure-tone audiometry averages (500-1000-2000-4000 Hz) within the normal range (≤25 dB HL), Having no chronic tinnitus complaint, The mean scores on the questions assessing the ability to understand speech in noise in the \"Speech Perception\" subscale of the SSQ (Speech, Spatial, and Hearing Quality Scale) are below the normative value, Scoring 21 or above on the MoCA test, Having no emotional or neurological problems that could interfere with the tests.\n\nExclusion Criteria\n\nPresence of peripheral and\u002For central hearing loss, Presence of somatosensory tinnitus, Presence of emotional and\u002For neurological problems that could interfere with the tests.",[19],{"name":20,"affiliation":5,"role":21},"Eyyup Kara, Asst. Prof.","STUDY_CHAIR",[23],{"name":24,"role":25,"phone":26,"phoneExt":10,"email":27},"Cem Yeral, MSc","CONTACT","+90 539 402 78 46","cem.yeral@ogr.iuc.edu.tr",[29],{"facility":30,"status":31,"city":32,"state":10,"zip":10,"country":33,"countryCode":10,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Istanbul University-Cerrahpaşa","RECRUITING","Istanbul","Turkey (Türkiye)",{"type":35,"coordinates":36},"Point",[37,38],28.94966,41.01384,{"lat":38,"lon":37},[41,45],{"name":42,"role":25,"phone":43,"phoneExt":10,"email":44},"Institute of Graduate Studies","+90 212 404 03 00 - 53101","lisansustuegitim@iuc.edu.tr",{"name":20,"role":46,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Cem Yeral","Research Assistant Cem Yeral",[52],{"name":53,"class":6},"Medipol University","100610642","relationship-between-ls-chirp-abr-and-speech-in-noise-skills-in-hidden-hearing-loss-100610642",false,"NCT07230236","Relationship Between LS Chirp ABR and Speech-in-Noise Skills in Hidden Hearing Loss","Investigation of the Relationship Between LS Chirp ABR and Comprehension In Noise Skills In Individuals With Suspected Hidden Hearing Loss","Inclusion Criteria (Control group):\n\n* Being between 20 and 60 years of age,\n* Having bilateral pure-tone audiometry averages (500-1000-2000-4000 Hz) within the normal range (≤25 dB HL),\n* Having no tinnitus or auditory complaints,\n* Scoring 21 or above on the MoCA test,\n* Having no emotional or neurological problems that could interfere with the tests.\n\nExclusion Criteria (Control group):\n\n* Presence of peripheral and\u002For central hearing loss,\n* Presence of somatosensory tinnitus,\n* Presence of emotional and\u002For neurological problems that could interfere with the tests.\n\nInclusion Criteria (First study group):\n\n* Being between 20 and 60 years of age,\n* Having bilateral pure-tone audiometry averages (500-1000-2000-4000 Hz) within the normal range (≤25 dB HL),\n* Having a chronic tinnitus complaint (≥3 months),\n* Scoring 21 or above on the MoCA test,\n* Having no emotional or neurological problems that could interfere with the tests.\n\nExclusion Criteria (First study group):\n\n* Presence of peripheral and\u002For central hearing loss,\n* Presence of somatosensory tinnitus,\n* Presence of emotional and\u002For neurological problems that could interfere with the tests.\n\nInclusion Criteria (Second study group):\n\n* Being between 20 and 60 years of age,\n* Having bilateral pure-tone audiometry averages (500-1000-2000-4000 Hz) within the normal range (≤25 dB HL),\n* Having no chronic tinnitus complaint,\n* Having an average score below 4.3 on the \"Speech Perception\" subscale of the Speech, Spatial and Qualities of Hearing Scale (SSQ),\n* Scoring 21 or above on the MoCA test,\n* Having no emotional or neurological problems that could interfere with the tests.\n\nExclusion Criteria (Second study group):\n\n* Presence of peripheral and\u002For central hearing loss,\n* Presence of somatosensory tinnitus,\n* Presence of emotional and\u002For neurological problems that could interfere with the tests.",true,"ALL","20 Years","60 Years",{"count":66,"type":67},63,"ESTIMATED","10 Months","OBSERVATIONAL","It is known that the underlying problem in Hidden Hearing Loss (HHL) is cochlear synaptopathy (CS) and that low-spontaneous-rate auditory nerve fibers play an important role in this pathology. Therefore, it is suggested that low-spontaneous-rate auditory nerve fibers are damaged in HHL. Consequently, LS CE-Chirp-evoked ABR and HINT, which assesses CS by presenting stimuli of varying intensities and characteristics to provide information about auditory nerve fibers, will be used to evaluate participants both objectively and subjectively.\n\nAim of the study:\n\nThe main aim of this study is to investigate the relationship between the amplitude and latency values obtained with LS CE-Chirp-stimulated ABR and the critical Signal-to-Noise Ratio (SNR) obtained from the Hearing in Noise Test (HINT) in individuals suspected of having HHL.\n\nHypotheses\n\nH0: In individuals suspected of having HHL, there is no relationship between the amplitude values of waves I, III, and V obtained with LS CE-Chirp ABR at 80, 90, and 100 dBnHL and the I\u002FV amplitude ratio and the critical SNR obtained from HINT.\n\nH1: In individuals suspected of having HHL, there is a relationship between the amplitude values of waves I, III, and V obtained with LS CE-Chirp ABR at 80, 90, and 100 dBnHL and the I\u002FV amplitude ratio, and the critical SNR obtained from HINT.\n\nExpected Results:\n\nThe study will reveal how LS CE-Chirp stimulation affects ABR results in individuals suspected of having HHL, and the relationship between these results and HINT results will be examined. In this way, HHL will be evaluated both objectively (LS CE-Chirp ABR) and subjectively (HINT). Based on the findings, scientific outputs such as publications or projects are targeted.\n\nImportance:\n\nHHL has recently attracted increasing attention as a condition that significantly affects daily life. In today's world, where noise and noisy environments are prevalent, disadvantages arise in many aspects, particularly in communication. Therefore, the findings obtained in this study may contribute to a better understanding of HHL.",[72,73],"Hidden Hearing Loss","Cochlear Synaptopathy",[75,76,77,78],"hidden hearing loss","cochlear synaptopathy","Level-Specific (LS) Chirp ABR","Hearing In Noise Test (HINT)","2025-11-14",{"date":81,"type":82},"2025-11-17","ACTUAL",{"date":84,"type":82},"2025-08-20",{"date":86,"type":67},"2026-06-01",{"name":5,"class":6},1]