[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553467":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":24,"centralContacts":28,"locations":39,"responsibleParty":87,"collaborators":89,"id":95,"slug":96,"hasResults":97,"nctId":98,"briefTitle":99,"officialTitle":100,"acronym":101,"eligibilityCriteria":102,"healthyVolunteers":97,"sex":103,"minAge":104,"maxAge":33,"enrollmentInfo":105,"targetDuration":33,"studyType":108,"phases":109,"briefSummary":111,"conditions":112,"keywords":116,"overallStatus":62,"whyStopped":33,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":133},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Minimally-trained operators","Group A: Minimally trained operators for LVOT VTI measurement will be intensive care residents and medical students having done less than 20 transthoracic echocardiography (TTE). All untrained operators will benefit from a standardized preliminary minimal training to teach them how to obtain apical 5-chamber view and acquire LVOT VTI using pulsed-wave Doppler according to the guidelines of the American Society of Echocardiography.",[12],"Other: Fluid challenge (cristalloids) OR passive leg raising",{"label":14,"type":6,"description":15,"interventionNames":16},"Expert operators","Group B: Experts are ICU attending physicians considered experienced and competent in TTE (either board certified or considered as experts locally). Experts will also be trained in using the same ultrasound platform equipped with the Ultrasight AI software. All operators will be trained on the same ultrasound platform: Philips Lumify® equipped with the Ultrasight AI software to optimize the quality of the 5-chamber views.",[12],[18],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":22},"Fluid challenge (cristalloids) OR passive leg raising","Patients in whom fluid administration is considered necessary, based on hypoperfusion criteria will be included in the trial.\n\nOne member of group A and one of group B will proceed independently to evaluate LVOT VTI, guided by the UltraSight AI software to obtain the best 5-chamber view. The measure of LVOT VTI will be calculated as the average of three consecutive cardiac cycles.\n\nThe order of acquisition between group A and B will be randomized. Each operator will be blinded to the values obtained by the other.\n\nAfter baseline LVOT VTI measurement, a 250 mL fluid challenge of crystalloids or a passive leg raising test (non-pharmacological and reversible fluid challenge of roughly 250 mL), depending on the appreciation of the clinician will be performed. Measurements will be repeated immediately after the fluid challenge by the same operators, still blinded to each other, guided by the UltraSight AI software. The order of the 2nd acquisition will be the same as the 1st acquisition",[14,9],[23],"Volume expansion",[25],{"name":26,"affiliation":5,"role":27},"Bernard MD Cholley, PhD","PRINCIPAL_INVESTIGATOR",[29,35],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},"Bernard Cholley","CONTACT","0156092515",null,"bernard.cholley@aphp.fr",{"name":36,"role":31,"phone":37,"phoneExt":33,"email":38},"Cléo Bourgeois","0156095638","cleo.bourgeois@aphp.fr",[40,60,77],{"facility":41,"status":42,"city":43,"state":33,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"CHU de Limoges","NOT_YET_RECRUITING","Limoges","87042","France","FR",{"type":48,"coordinates":49},"Point",[50,51],1.24759,45.83362,{"lat":51,"lon":50},[54,58],{"name":55,"role":31,"phone":56,"phoneExt":33,"email":57},"Philippe MD Vignon, PHD","0555058835","philippe.vignon@unilim.fr",{"name":59,"role":27,"phone":33,"phoneExt":33,"email":33},"Philippe Vignon, PhD",{"facility":61,"status":62,"city":63,"state":33,"zip":64,"country":45,"countryCode":46,"cosmosGeoPoint":65,"geoPoint":69,"contacts":70},"Hôpital Lariboisière - APHP","RECRUITING","Paris","75010",{"type":48,"coordinates":66},[67,68],2.3488,48.85341,{"lat":68,"lon":67},[71,75],{"name":72,"role":31,"phone":73,"phoneExt":33,"email":74},"Benjamin MD Chousterman, PhD","0149958512","benjamin.chousterman@aphp.fr",{"name":76,"role":27,"phone":33,"phoneExt":33,"email":33},"Benjamin Chousterman, PhD",{"facility":78,"status":62,"city":63,"state":33,"zip":79,"country":45,"countryCode":46,"cosmosGeoPoint":80,"geoPoint":82,"contacts":83},"Hôpital européen Georges Pompidou - APHP","75015",{"type":48,"coordinates":81},[67,68],{"lat":68,"lon":67},[84,85],{"name":26,"role":31,"phone":32,"phoneExt":33,"email":34},{"name":86,"role":27,"phone":33,"phoneExt":33,"email":33},"Bernard Cholley, PhD",{"type":88,"investigatorFullName":33,"investigatorTitle":33,"investigatorAffiliation":33,"oldNameTitle":33,"oldOrganization":33},"SPONSOR",[90,93],{"name":91,"class":92},"Philips Healthcare","INDUSTRY",{"name":94,"class":92},"UltraSight","100553467","reliability-of-minimally-trained-operators-velocity-time-integral-measurement-guided-by-artificial-intelligence-vti-100553467",false,"NCT06486467","Reliability of Minimally Trained Operator's Velocity-Time Integral Measurement Guided by Artificial Intelligence VTI","Reliability of Minimally Trained Operator's Velocity-Time Integral Measurement Guided by Artificial Intelligence (MiniTrained-VTI)","MiniTrainedVTI","Inclusion criteria:\n\nAll patients aged 18 and more\n\nHospitalized in ICU, in whom fluid administration is considered necessary by the clinician in charge, based on the presence of hypoperfusion criterion:\n\n* \\>10% decrease in mean arterial pressure with respect to baseline value\n* Skin mottling, oliguria (\\\u003C0,5 ml\u002Fkg\u002Fh)\n* change in the level of consciousness\n* hyperlactatemia\n* decrease in central venous oxygen saturation Affiliation to a French social security system (beneficiary or legal) Participant's or next of kin non-opposition or emergency procedure\n\nExclusion Criteria:\n\nPatients with atrial fibrillation, due to the higher variability in LVOT VTI; Patient on Emergency Medical Assistance; Patient under guardianship, curatorship, deprived of liberty.","ALL","18 Years",{"count":106,"type":107},100,"ESTIMATED","INTERVENTIONAL",[110],"NA","Stroke volume is a major determinant of tissue perfusion and therefore a key parameter to monitor in patients with hemodynamic instability and hypoperfusion. Left Ventricular Outflow Tract (LVOT) Velocity-Time Integral (VTI) measured using pulsed wave Doppler is widely used as an estimation of stroke volume and should be a competence required for every Intensive Care Unit (ICU) physician. Recently, research in Artificial Intelligence (AI) applied to medical imaging constituted a breakthrough in the acquisition of images. The goal of the present study is to characterize and quantify the reliability and reproducibility of LVOT VTI measurements by comparing the measures obtained by minimally-trained operators and expert physicians, guided by UltraSight AI software.",[113,114,115],"Velocity-time Integral Measurement","Critically Ill Patients","Tissue Hypoperfusion",[117,118,119,120,121,122,123],"Velocity-time integral","Echocardiography","Artificial Intelligence","Minimally-trained operator","Reproducibility","Fluid challenge","Fluid responsiveness","2026-04-20",{"date":126,"type":127},"2026-04-21","ACTUAL",{"date":129,"type":127},"2024-11-14",{"date":131,"type":107},"2026-05-15",{"name":5,"class":6},3]