[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100415814":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":45,"responsibleParty":143,"collaborators":26,"id":145,"slug":146,"hasResults":147,"nctId":148,"briefTitle":149,"officialTitle":150,"acronym":151,"eligibilityCriteria":152,"healthyVolunteers":147,"sex":153,"minAge":154,"maxAge":155,"enrollmentInfo":156,"targetDuration":26,"studyType":159,"phases":160,"briefSummary":162,"conditions":163,"keywords":167,"overallStatus":48,"whyStopped":26,"lastUpdateSubmitDate":171,"lastUpdatePostDateStruct":172,"startDateStruct":175,"completionDateStruct":177,"leadSponsor":179,"locationsCount":180},{"fullName":5,"class":6},"Lille Catholic University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Remediation program via a \"serious game\"","EXPERIMENTAL","Classic care (recommended by the French Haute Autorité de Santé) accompanied by cognitive remediation by \"serious game\"",[13],"Diagnostic Test: Serious game",{"label":15,"type":16,"description":17,"interventionNames":18},"Classic care (French Haute Autorité de Santé)","PLACEBO_COMPARATOR","Classic care (recommended by French Haute Autorité de Santé)",[19],"Diagnostic Test: Usual HAS care",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIAGNOSTIC_TEST","Serious game","The serious game is accessible via an online platform, on a tablet: 4 20-minutes activities sessions per week must be carried out.\n\nThe program format in the serious game form makes possible to simultaneously understand a large number of cognitive functions.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Usual HAS care","The control group patients will follow the care they need, according to the HAS recommendations. Non-specific cognitive activities notebooks will be provided to them. They will be instructed to perform the 4 20-minutes sessions per week for 4 months.",[15],[32],{"name":33,"affiliation":34,"role":35},"Bruno Lenne","Hôpital Saint-Vincent de Paul","PRINCIPAL_INVESTIGATOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Amélie Lausiaux, MD, PhD","CONTACT","03.20.22.52.69","lansiaux.amelie@ghicl.net",{"name":43,"role":39,"phone":40,"phoneExt":26,"email":44},"Elodie Moutailler","moutailler.elodie@ghicl.net",[46,66,80,95,109,127],{"facility":47,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"CH Arras","RECRUITING","Arras","Hauts-de-France","62000","France","FR",{"type":55,"coordinates":56},"Point",[57,58],2.78186,50.29301,{"lat":58,"lon":57},[61,65],{"name":62,"role":39,"phone":63,"phoneExt":26,"email":64},"Patrick LE COZ","03 21 21 13 60","Patrick.LE-COZ@ch-arras.fr",{"name":62,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":67,"status":48,"city":68,"state":50,"zip":69,"country":52,"countryCode":53,"cosmosGeoPoint":70,"geoPoint":74,"contacts":75},"CH LENS","Lens","62300",{"type":55,"coordinates":71},[72,73],2.82791,50.43302,{"lat":73,"lon":72},[76,79],{"name":77,"role":39,"phone":26,"phoneExt":26,"email":78},"Julien LANNOY","jlannoy@ch-lens.fr",{"name":77,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":81,"status":48,"city":82,"state":50,"zip":83,"country":52,"countryCode":53,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"CHRU","Lille","59000",{"type":55,"coordinates":85},[86,87],3.05512,50.63391,{"lat":87,"lon":86},[90,94],{"name":91,"role":39,"phone":92,"phoneExt":26,"email":93},"Camille Jougleux","06 09 76 13 29","Caroline.VIE@CHRU-LILLE.FR",{"name":91,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":96,"status":48,"city":82,"state":50,"zip":83,"country":52,"countryCode":53,"cosmosGeoPoint":97,"geoPoint":99,"contacts":100},"Saint Vincent hospital",{"type":55,"coordinates":98},[86,87],{"lat":87,"lon":86},[101,104,105,107],{"name":102,"role":39,"phone":26,"phoneExt":26,"email":103},"Bruno Lenne, MD","lenne.bruno@ghicl.net",{"name":33,"role":35,"phone":26,"phoneExt":26,"email":26},{"name":106,"role":35,"phone":26,"phoneExt":26,"email":26},"Julien Poupart",{"name":108,"role":35,"phone":26,"phoneExt":26,"email":26},"Arnaud Kwiatkowski",{"facility":110,"status":48,"city":111,"state":112,"zip":113,"country":52,"countryCode":53,"cosmosGeoPoint":114,"geoPoint":118,"contacts":119},"Saint-Philibert hospital","Lomme","Nord","59462",{"type":55,"coordinates":115},[116,117],2.98715,50.64358,{"lat":117,"lon":116},[120,122,124,125],{"name":121,"role":39,"phone":40,"phoneExt":26,"email":41},"Lansiaux Amélie, MD, PhD",{"name":123,"role":39,"phone":40,"phoneExt":26,"email":44},"Moutailler Elodie",{"name":102,"role":35,"phone":26,"phoneExt":26,"email":26},{"name":126,"role":35,"phone":26,"phoneExt":26,"email":26},"Cécile Donzé, MD",{"facility":128,"status":48,"city":129,"state":130,"zip":131,"country":52,"countryCode":53,"cosmosGeoPoint":132,"geoPoint":136,"contacts":137},"Charles Nicolle Hospital","Rouen","Normandy","76000",{"type":55,"coordinates":133},[134,135],1.09932,49.44313,{"lat":135,"lon":134},[138,142],{"name":139,"role":39,"phone":140,"phoneExt":26,"email":141},"Bertrand Bourre","02 32 88 33 99","Bertrand.Bourre@chu-rouen.fr",{"name":139,"role":35,"phone":26,"phoneExt":26,"email":26},{"type":144,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100415814","remediation-program-via-a-serious-game-for-the-cognitive-functions-of-multiple-sclerosis-patients-100415814",false,"NCT04694534","Remediation Program Via a \"Serious Game\" for the Cognitive Functions of Multiple Sclerosis Patients","e-SEP Cognition: Effectiveness of a Remediation Program Via a \"Serious Game\" on the Cognitive Functions of Multiple Sclerosis Patients: Controlled, Randomized, Multicentric Trial","E-SEP","Inclusion Criteria:\n\n* Relapsing-remitting or progressive multiple sclerosis people defined according to Mc Donald's criteria revised in 2005\n* Age between ≥ 18 and ≤ 65 years old\n* Cognitive complaint, with at least one deficient score at the initial neuropsychological examination (\\\u003C5th percentile of the reference group), one of the scores of which concerns at least one BICAMS test\n* Have not had a definite relapse for at least 6 weeks\n* Be at least 4 weeks away from a corticosteroid bolus\n* Lack of neuroleptic treatment\n* Patient with an Internet connection\n* Signed informed consent\n\nExclusion Criteria:\n\n* Severe cognitive deficit defined by obtaining a deficit score in more than six cognitive processes at the initial neuropsychological assessment.\n* Neuropsychological care\n* Inability to receive oral and written information\n* Inability to use the software (due in particular to motor and \u002F or sensory difficulties),\n* Neurological or psychiatric comorbidity, other than MS and anxiodepressive syndrome\n* Patient with severe anxiodepressive syndrome (BDI\\> 27)\n* Participation in an interventional study on cognitive functions\n* Patient under legal protection, guardianship or curatorship\n* Pregnant or breastfeeding women","ALL","18 Years","65 Years",{"count":157,"type":158},150,"ESTIMATED","INTERVENTIONAL",[161],"NA","The main goal of this study is to assess the effectiveness of a cognitive remediation program based on a \"serious game\" on the information processing speed evolution and the process of learning via episodic memory in multiple sclerosis patients.",[164,165,166],"Multiple Sclerosis","Memory","Learning",[168,23,169,170],"Multiple sclerosis","Episodic memory learning capacities","Information processing speed capacities","2025-09-03",{"date":173,"type":174},"2025-09-04","ACTUAL",{"date":176,"type":174},"2021-10-08",{"date":178,"type":158},"2027-03-01",{"name":5,"class":6},6]