[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560950":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":26,"centralContacts":27,"locations":33,"responsibleParty":46,"collaborators":48,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":26,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":26,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":26,"overallStatus":36,"whyStopped":26,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Egymedicalpedia","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A: Remifentanil Group","ACTIVE_COMPARATOR","About 35 Patients will receive Remifentanil bolus of 1 μg\u002Fkg over 30 seconds followed by a continuous infusion of 0.03-0.05 μg\u002Fkg\u002Fmin.",[13],"Drug: Remifentanil",{"label":15,"type":10,"description":16,"interventionNames":17},"Group B: Remimazolam Group","About 35 Patients will receive remimazolam bolus of 0.2mg\u002Fkg followed by a continuous infusion of 0.3-0.5 μg\u002Fkg\u002Fh.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","Remifentanil","to compare remifentanil and remimazolam to limit patient movement during long-eye surgeries under local anesthesia.",[9,15],[25],"emimazolam",null,[28],{"name":29,"role":30,"phone":31,"phoneExt":26,"email":32},"Ahmed M. Elnagar, M.D","CONTACT","+201007529357","Ahmed.elnaggar@azhar.edu.eg",[34],{"facility":35,"status":36,"city":37,"state":26,"zip":26,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":26},"Al-Azhar University hospitals","RECRUITING","Cairo","Egypt","EG",{"type":41,"coordinates":42},"Point",[43,44],31.24967,30.06263,{"lat":44,"lon":43},{"type":47,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[49],{"name":50,"class":51},"Al-Azhar University","OTHER","100560950","remifentanil-and-remimazolam-to-limit-patient-movement-100560950",false,"NCT06583811","Remifentanil and Remimazolam to Limit Patient Movement","Remifentanil and Remimazolam to Limit Patient Movement During Long-Eye Surgeries Under Local Anesthesia","Inclusion Criteria:\n\n* Age \\> 40 years.\n* Both sexes.\n* American Society of Anesthesiology (ASA) physical status I-III.\n* Undergoing long-eye surgeries under local anesthesia using peribulbar block with an expected surgical time of more than one hour.\n\nExclusion Criteria:\n\n* Patients on aspirin or anticoagulants.\n* Allergy to any study medication.\n* Drug abuse.\n* Uncontrolled hypertension.\n* Hyperthyroidism.\n* Frequent cough.\n* Impaired hearing.\n* Severe liver and kidney dysfunction.\n* Neurological or psychological disorders.\n* Partial or failed block.","ALL","40 Years","50 Years",{"count":63,"type":64},70,"ESTIMATED","INTERVENTIONAL",[67],"NA","Local anesthetics (LA) may be administered by injection (retrobulbar, peribulbar, subconjunctival, lid, or facial block) or by instillation (topical anesthesia), Considerable drawbacks of local anesthesia in these patients include the fact that a few patients can remain comfortable on an operating table for procedures that exceed two or three hours.\n\nSedation may be helpful with LA to decrease the experience of discomfort, movement and anxiety, which may in turn positively influence hemodynamic parameters, patient satisfaction, and overall improve surgical safety. Sedatives used in eye surgeries include benzodiazepines, opioids, alpha-adrenoceptor agonists, and propofol.",[70],"Long-Eye Surgeries","2024-08-31",{"date":73,"type":74},"2024-09-04","ACTUAL",{"date":76,"type":74},"2024-07-10",{"date":78,"type":64},"2025-01-10",{"name":5,"class":6},1]