[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639436":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":23,"centralContacts":23,"locations":23,"responsibleParty":26,"collaborators":23,"id":30,"slug":31,"hasResults":32,"nctId":33,"briefTitle":34,"officialTitle":35,"acronym":23,"eligibilityCriteria":36,"healthyVolunteers":32,"sex":37,"minAge":38,"maxAge":39,"enrollmentInfo":40,"targetDuration":23,"studyType":43,"phases":44,"briefSummary":46,"conditions":47,"keywords":23,"overallStatus":49,"whyStopped":23,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":23},{"fullName":5,"class":6},"Future University in Egypt","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"S-PRG barrier coat","EXPERIMENTAL","varnish containing Surface pre-reacted glass-ionomer technology",[13],"Other: S-PRG barrier coat",{"label":15,"type":16,"description":17,"interventionNames":18},"Profluorid Varnish","ACTIVE_COMPARATOR","Fluoride varnish",[19],"Other: Profluorid Varnish",[21,24],{"type":6,"name":9,"description":11,"armGroupLabels":22,"otherNames":23},[9],null,{"type":6,"name":15,"description":17,"armGroupLabels":25,"otherNames":23},[15],{"type":27,"investigatorFullName":28,"investigatorTitle":29,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"PRINCIPAL_INVESTIGATOR","Mazin Mohamed Ibrahim","Master's degree Student","100639436","remineralization-potential-of-bioactive-varnish-100639436",false,"NCT07602660","Remineralization Potential of Bioactive Varnish","Remineralization Potential of Bioactive Varnish Versus Sodium Fluoride Varnish in Management of White Spot Lesions: Randomized Controlled Trial","Inclusion Criteria:\n\n1. Patients within 16-35 years of age.\n2. Each patient has 4 or more WSLs\n3. Mild and moderate WSLs.\n4. Good oral hygiene and willing patients who can attend study visits.\n5. Symmetrical number of permanent teeth in each arch (mesial to second molars).\n\nExclusion Criteria:\n\n1. Active carious lesions.\n2. Labial surface restorations.\n3. Intrinsic and extrinsic stains.\n4. Patients who have a significant medical history or if they are smokers.\n5. Patients who participated in clinical study during the preceding six months of the start of this trial.\n6. Criteria for discontinuation; Mortality and acquiring severe debilitating disease.","ALL","16 Years","35 Years",{"count":41,"type":42},60,"ESTIMATED","INTERVENTIONAL",[45],"NA","This randomized controlled trial is held to investigate the effectiveness of two remineralizing agents surface pre-reacted glass-ionomer (S-PRG) filler and fluoride in management of white spot lesions.",[48],"White Spot Lesion","NOT_YET_RECRUITING","2026-05-16",{"date":52,"type":53},"2026-05-22","ACTUAL",{"date":55,"type":42},"2026-06",{"date":57,"type":42},"2026-12",{"name":5,"class":6}]