[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100351429":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":39,"locations":46,"responsibleParty":63,"collaborators":66,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":25,"eligibilityCriteria":80,"healthyVolunteers":76,"sex":81,"minAge":82,"maxAge":25,"enrollmentInfo":83,"targetDuration":25,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":25,"overallStatus":49,"whyStopped":25,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Helsinki University Central Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"RIPC","EXPERIMENTAL","RIPC will consist of setting a tourniquet to donor thigh and inflating it to 300mmHg four times 5 minutes with 5 minutes deflating in between each. RIPC-intervention will be performed twice: First after brain death and second time before procurement procedure.",[13],"Procedure: RIPC",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham-RIPC","SHAM_COMPARATOR","Sham-RIPC will consist of setting a tourniquet to donor thigh without inflating it and keeping it in place for 35 min. Sham-RIPC-intervention will be performed twice: First after brain death and second time before procurement procedure.",[19],"Procedure: Sham-RIPC",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Remote Ischaemic Preconditioning",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Sham procedure",[15],[30,33,36],{"name":31,"affiliation":5,"role":32},"Aki Uutela, MD","PRINCIPAL_INVESTIGATOR",{"name":34,"affiliation":5,"role":35},"Ville Sallinen, MD, PhD","STUDY_DIRECTOR",{"name":37,"affiliation":5,"role":38},"Marko Lempinen, MD, PhD","STUDY_CHAIR",[40,44],{"name":34,"role":41,"phone":42,"phoneExt":25,"email":43},"CONTACT","+358-9-4711","ville.sallinen@helsinki.fi",{"name":31,"role":41,"phone":42,"phoneExt":25,"email":45},"aki.uutela@hus.fi",[47],{"facility":48,"status":49,"city":50,"state":25,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Helsinki University Hospital","RECRUITING","Helsinki","00029","Finland","FI",{"type":55,"coordinates":56},"Point",[57,58],24.93545,60.16952,{"lat":58,"lon":57},[61,62],{"name":34,"role":41,"phone":42,"phoneExt":25,"email":43},{"name":31,"role":41,"phone":42,"phoneExt":25,"email":45},{"type":32,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Ville Sallinen","MD, PhD, Adj. Prof., Consultant",[67,70,72],{"name":68,"class":69},"Finska Läkaresällskapet (funding)","UNKNOWN",{"name":71,"class":6},"Academy of Finland",{"name":73,"class":69},"Helsinki University Hospital Research Funds (funding)","100351429","remote-ischaemic-preconditioning-in-transplantation-riptrans-100351429",false,"NCT03855722","Remote Ischaemic Preconditioning in Transplantation (RIPTRANS)","Remote Ischaemic Preconditioning in Transplantation (RIPTRANS) - A Prospective Randomized Controlled Trial","Donor Inclusion Criteria:\n\n* Brain-dead organ donor with a plan of harvesting at least one kidney\n\nDonor Exclusion Criteria:\n\n* Haemodynamically unstable donor\n* Age below 18 years\n* Planned organ recipients are recruited to another prospective trial, which prevents participation in this trial.\n\nAll organ recipients receiving organs (kidney, liver, pancreas-kidney, heart, lungs) from a randomized donor will be recruited providing that the recipient surgery is performed at Helsinki University Hospital, recipient is over 18 years old, and recipient gives written informed consent to participate in the trial.","ALL","18 Years",{"count":84,"type":85},496,"ESTIMATED","INTERVENTIONAL",[88],"NA","Remote ischemic preconditioning (RIPC) is a concept where remotely induced ischemia produces protection against ischemia-reperfusion injury in a remote organ. RIPC has been studied extensively in animal models and heart surgery, but it's benefit in transplantation has been studied less. The primary aim of this study is to find out whether RIPC performed in a donor in donation after brain-death (DBD) could improve delayed graft function rate of kidney transplants.",[91],"Transplant Dysfunction","2020-03-06",{"date":94,"type":95},"2020-03-10","ACTUAL",{"date":97,"type":95},"2019-03-12",{"date":99,"type":85},"2042-02",{"name":5,"class":6},1]