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During the inflation period, the blood pressure cuff is inflated to 200 mmHg to stop blood flow in the arm.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Simulated RIPC (Sham)","The procedure will be performed by using an electric auto-control device (modified blood pressure monitor for remote ischemic conditioning, Seagull Healthcare Aps, Denmark) for Remote Ischemic Conditioning in the arm. 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Criteria:\n\n≥18 years old NHL, HL or breast cancer diagnosis Scheduled to undergo chemotherapy including ≥ 240 mg\u002Fk2 cumulative dose of anthracyclines.\n\nPre-chemo LVEF \\>40% on screening echocardiography.\n\nPresence of ≥1 of the following risk factors for developing cardiotoxicity:\n\nPrevious coronary artery disease (any of the following):\n\nPrevious coronary revascularisation (PCI or CABG) or Medical history of previous significant nonrevascularized coronary stenosis Previous Acute Coronary Syndrome \u002F Acute Myocardial Infarction with a LVEF \\> 40 LVEF 41-54% Age ≥ 65 years old Previous diagnosis of arterial hypertension (with or without treatment) Chronic kidney disease (estimated glomerular filtration rate \\\u003C60ml\u002Fmin\u002F1.73m2) Current or former smoker. Obesity (BMI≥30 kg\u002Fm2) LVH on screening echocardiography (LV thickness ≥12mm). High alcohol intake (≥21 alcoholic beverages per week) Sinus rhythm on screening ECG Previous diagnosis of diabetes (except those treated with sulfonylureas or those with neuropathy) Previous non-anthracycline-based chemotherapy Signed Informed Consent Form (ICF)\n\nExclusion Criteria:\n\n* History of any of the following diseases:\n\n  * Any cancer who received anthracyclines treatment before the index episode.\n  * Previous clinical diagnosis of heart failure.\n  * Permanent atrial fibrillation (AF).\n  * Severe valvular or sub-valvular heart disease.\n  * Severe peripheral arterial disease in the upper extremities or arteriovenous (AV) shunt in the arm selected for RIPC.\n* Clinical diagnosis of diabetes neuropathy\n* Contraindication for CMR:\n\n  * Severe claustrophobia.\n  * Any device which is known to threaten or pose hazard in all MR environments (http:\u002F\u002Fwww.mrisafety.com\u002F).\n  * Patients with implanted biomedical cardiac devices: pacemakers, ICDs or CRT.\n* Severe thrombocytopenia (platelets \\\u003C50,000\u002FµL) on any blood test within the previous 3 months.\n* Patients participating in other clinical trials.\n* Impossibility to consent or undergo study follow-ups.","ALL","18 Years","99 Years",{"count":311,"type":312},608,"ESTIMATED","INTERVENTIONAL",[315],"NA","Multinational, prospective, proof of concept phase II, double-blinded, sham-controlled, randomized clinical trial (RCT) to evaluate the efficacy and safety of Remote Ischaemic PreConditioning (RIPC) in Lymphoma patients receiving anthracyclines.",[318,319],"Anthracycline-induced Cardiac Toxicity","Lymphoma","2025-09-12",{"date":322,"type":323},"2025-09-18","ACTUAL",{"date":325,"type":323},"2022-01-18",{"date":327,"type":312},"2026-12",{"name":5,"class":6},24]