[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589379":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":85,"collaborators":18,"id":87,"slug":88,"hasResults":89,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":93,"eligibilityCriteria":94,"healthyVolunteers":89,"sex":95,"minAge":96,"maxAge":97,"enrollmentInfo":98,"targetDuration":18,"studyType":101,"phases":102,"briefSummary":104,"conditions":105,"keywords":108,"overallStatus":113,"whyStopped":18,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},{"fullName":5,"class":6},"University of Kansas Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"HIIT Group","EXPERIMENTAL","The intervention will consist of three 30-minute training sessions\u002Fweek, each starting with a five-minute warm-up, followed by 20 minutes of interval training, and ending with a five-minute cool-down. The interval training will consist of 10 alternating high- and low-intensity intervals, with a 1:1 work-to-rest ratio (one minute of high intensity followed by one minute of low-moderate intensity).",[13],"Behavioral: High Intensity Interval Training",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","NO_INTERVENTION","Participants will receive a handout and information on exercise.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","High Intensity Interval Training","The intervention will consist of three 30-minute training sessions\u002Fweek, each starting with a five-minute warm-up, followed by 20 minutes of interval training, and ending with a five-minute cool-down. The interval training will consist of 10 alternating high- and low-intensity intervals, with a 1:1 work-to-rest ratio (one minute of high intensity followed by one minute of low-moderate intensity). As participants' fitness improves, the interval intensity will increase accordingly.",[9],[26],{"name":27,"affiliation":28,"role":29},"Anthony Sung, MD","The University of Kansas Cancer Center","PRINCIPAL_INVESTIGATOR",[31],{"name":32,"role":33,"phone":34,"phoneExt":18,"email":35},"Anthony Sung","CONTACT","913-588-6030","asung2@kumc.edu",[37,53,69],{"facility":38,"status":18,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"University of Kansas Cancer Center","Kansas City","Kansas","66160","United States","US",{"type":45,"coordinates":46},"Point",[47,48],-94.62746,39.11417,{"lat":48,"lon":47},[51,52],{"name":27,"role":33,"phone":34,"phoneExt":18,"email":35},{"name":27,"role":29,"phone":18,"phoneExt":18,"email":18},{"facility":54,"status":18,"city":55,"state":56,"zip":57,"country":42,"countryCode":43,"cosmosGeoPoint":58,"geoPoint":62,"contacts":63},"Duke University","Durham","North Carolina","27705",{"type":45,"coordinates":59},[60,61],-78.89862,35.99403,{"lat":61,"lon":60},[64,68],{"name":65,"role":33,"phone":66,"phoneExt":18,"email":67},"Amy Pastva, MD","919-681-4380","amy.pastva@duke.edu",{"name":65,"role":29,"phone":18,"phoneExt":18,"email":18},{"facility":70,"status":18,"city":71,"state":72,"zip":73,"country":42,"countryCode":43,"cosmosGeoPoint":74,"geoPoint":78,"contacts":79},"The University of Texas MD Anderson Cancer Center","Houston","Texas","77030",{"type":45,"coordinates":75},[76,77],-95.36327,29.76328,{"lat":77,"lon":76},[80,84],{"name":81,"role":33,"phone":82,"phoneExt":18,"email":83},"Ajay Sheshadri, MD","713-563-1987","asheshadri@mdanderson.org",{"name":81,"role":29,"phone":18,"phoneExt":18,"email":18},{"type":86,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100589379","remotely-monitored-mobile-health-supported-high-intensity-interval-training-before-hematopoietic-stem-cell-transplant-100589379",false,"NCT06953648","Remotely Monitored, Mobile Health-supported, High Intensity Interval Training Before Hematopoietic Stem Cell Transplant","Remotely Monitored, Mobile Health-supported, High Intensity Interval Training Before Hematopoietic Stem Cell Transplantation (REMM-HIIT-HCT)","REMM-HIIT","Inclusion Criteria:\n\n* Plan to undergo allogeneic hematopoietic stem cell transplant in 4-12 weeks after enrollment on this study.\n* Age 18-80 years\n* Able to read\u002Fwrite English (as many participant-reported outcome measures lack validated translations in other languages)\n\nExclusion Criteria:\n\n* Unable or unwilling to follow coaching\n* Functional impairment resulting in inability to exercise\n* Any absolute contraindications to exercise:\n\n  1. recent (\\\u003C6 months) acute cardiac event;\n  2. unstable angina;\n  3. uncontrolled dysrhythmias causing symptoms;\n  4. symptomatic aortic stenosis;\n  5. uncontrolled symptomatic heart failure;\n  6. acute pulmonary embolus;\n  7. acute myocarditis or pericarditis;\n  8. suspected or known dissecting aneurysm","ALL","18 Years","80 Years",{"count":99,"type":100},126,"ESTIMATED","INTERVENTIONAL",[103],"NA","The goal of this clinical trial is to learn how a remotely monitored high-intensity interval training (REMM-HIIT) affects the cardiorespiratory fitness and physical function for patients planning to undergo stem cell transplantation. The main questions it aims to answer are:\n\nIs there a change in the participant's cardiorespiratory fitness level? Is there a change in the participant's physical function?\n\nResearchers will compare the REMM-HIIT program to a control group of participants who do not take part in the training program to see if REMM-HIIT helps improve stem cell transplantation outcomes.\n\nParticipants will:\n\n* Complete cardiopulmonary exercise testing (CPET) 4 times during the study\n* Do basic tests to measure physical function 6 times during the study\n* Answer questions about their life and how they are feeling 6 times during the study\n* Wear a device to keep track of step counts and heart rate daily\n* Keep a log of every time they exercise throughout the study\n* Optionally, provide blood and stool samples 6 times during the study",[106,107],"Hematopoietic Stem Cell Transplantation","Cardiorespiratory Fitness",[22,109,106,110,111,112,107],"HIIT","Remote Monitoring","Mobile Health","Exercise","NOT_YET_RECRUITING","2025-04-23",{"date":116,"type":117},"2025-05-01","ACTUAL",{"date":119,"type":100},"2025-05",{"date":121,"type":100},"2030-03",{"name":5,"class":6},3]