[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630810":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":13,"locations":19,"responsibleParty":43,"collaborators":7,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":47,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":7,"studyType":59,"phases":7,"briefSummary":60,"conditions":61,"keywords":68,"overallStatus":22,"whyStopped":7,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Azienda Usl di Bologna","OTHER_GOV",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","Point of care ultrasound","Non-invasive bedside ultrasound assessment (renal Doppler and VExUS score) performed at baseline (≤6h from ICU admission), 24h, 48h, and 72h. No intervention is administered.",[14],{"name":15,"role":16,"phone":17,"phoneExt":7,"email":18},"Federico Moro, MD","CONTACT","0039 0516478215","federico.moro@ausl.bologna.it",[20],{"facility":21,"status":22,"city":23,"state":7,"zip":7,"country":24,"countryCode":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"Ospedale Maggiore C.A. Pizzardi AUSL Bologna","RECRUITING","Bologna","Italy","IT",{"type":27,"coordinates":28},"Point",[29,30],11.33875,44.49381,{"lat":30,"lon":29},[33,34,37,40,42],{"name":15,"role":16,"phone":17,"phoneExt":7,"email":18},{"name":35,"role":36,"phone":7,"phoneExt":7,"email":7},"Lorenzo Gamberini, MD","PRINCIPAL_INVESTIGATOR",{"name":38,"role":39,"phone":7,"phoneExt":7,"email":7},"Marco Tartaglione, MD","SUB_INVESTIGATOR",{"name":41,"role":39,"phone":7,"phoneExt":7,"email":7},"Valentina Chiarini, MD",{"name":15,"role":39,"phone":7,"phoneExt":7,"email":7},{"type":44,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100630810","renal-and-hepatic-abnormal-doppler-patterns-in-trauma-100630810",false,"NCT07492511","Renal and Hepatic Abnormal Doppler Patterns in Trauma","Renal and hEpatiC abnoRmal dopplEr pAtterns iN Trauma: a Multicentre Prospective Observational Study","RECREANT","Inclusion Criteria:\n\n* Age 18-65 years;\n* Admission within 24h from traumatic injury;\n* ISS \\>15\n\nExclusion Criteria:\n\n1. Age \\\u003C18 or \\>65;\n2. Known heart failure (NYHA ≥II);\n3. Chronic kidney disease (any stage) or chronic RRT;\n4. Chronic respiratory disease needing home O₂ or ventilation;\n5. Radiological evidence of vascular or parenchymal renal injury on trauma CT precluding reliable Doppler assessment","ALL","18 Years","65 Years",{"count":57,"type":58},350,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn about renal and hepatic blood flow abnormalities detected by bedside ultrasound in adult patients admitted to the intensive care unit (ICU) following major trauma.\n\nThe main questions it aims to answer are:\n\n* How reliably can trained operators measure renal Doppler and venous congestion scores (RDRI and VExUS) across different hospitals?\n* How common are abnormal kidney and liver blood flow patterns in major trauma patients during the first 72 hours of ICU admission?\n* Are these abnormal patterns associated with acute kidney injury or the need for mechanical ventilation?\n\nParticipants admitted to ICUs or high-dependency units (HDUs) with major trauma (Injury Severity Score \\>15) will undergo non-invasive bedside ultrasound assessments at admission and at 24, 48, and 72 hours. No additional treatments or interventions will be given as part of this study. Kidney function will also be checked at 6 months after hospital discharge.",[62,63,64,65,66,67],"Trauma (Including Fractures)","Trauma Patients","Kidney Disease","Hypovolemia","Hypervolemia","Kidney Failure",[69,70,71,72,73,74,75,76,77,78],"VEXUS","trauma","kidney injury","kidney failure","Venous congestion","renal perfusion","Renal Doppler resistive index","major trauma","Hemodynamic phenotyping","ICU","2026-03-19",{"date":81,"type":82},"2026-03-25","ACTUAL",{"date":84,"type":82},"2026-03-01",{"date":86,"type":58},"2030-06-30",{"name":5,"class":6},1]