[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100499383":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":11,"centralContacts":22,"locations":32,"responsibleParty":74,"collaborators":11,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":78,"sex":84,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":11,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":11,"overallStatus":34,"whyStopped":11,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"University Medical Center Groningen","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":11},"Hypothermic machine perfusion","NO_INTERVENTION",null,{"label":13,"type":14,"description":11,"interventionNames":15},"Normothermic machine perfusion","ACTIVE_COMPARATOR",[16],"Procedure: Normothermic machine perfusion",[18],{"type":19,"name":13,"description":20,"armGroupLabels":21,"otherNames":11},"PROCEDURE","To determine whether a 4-6 hour period of normothermic machine perfusion, following standard hypothermic machine perfusion, results in better graft function after transplantation, compared to hypothermic machine perfusion preservation alone of kidneys recovered from deceased donors aged 50 years or older",[13],[23,28],{"name":24,"role":25,"phone":26,"phoneExt":11,"email":27},"Cyril Moers, MD, PhD","CONTACT","0619602619","c.moers@umcg.nl",{"name":29,"role":25,"phone":30,"phoneExt":11,"email":31},"Kirsten Ma, PhD","0625651635","k.f.ma@umcg.nl",[33,49,62],{"facility":5,"status":34,"city":35,"state":36,"zip":11,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"RECRUITING","Groningen","Provincie Groningen","Netherlands","NL",{"type":40,"coordinates":41},"Point",[42,43],6.56667,53.21917,{"lat":43,"lon":42},[46],{"name":47,"role":25,"phone":48,"phoneExt":11,"email":27},"Cyril Moers, MD, PHD","+31619602619",{"facility":50,"status":51,"city":52,"state":11,"zip":11,"country":37,"countryCode":38,"cosmosGeoPoint":53,"geoPoint":57,"contacts":58},"Leiden University Medical Center","NOT_YET_RECRUITING","Leiden",{"type":40,"coordinates":54},[55,56],4.49306,52.15833,{"lat":56,"lon":55},[59],{"name":60,"role":25,"phone":61,"phoneExt":11,"email":11},"Dorottya de Vries, MD, PhD","+31715269111",{"facility":63,"status":34,"city":64,"state":11,"zip":11,"country":37,"countryCode":38,"cosmosGeoPoint":65,"geoPoint":69,"contacts":70},"Erasmus Medical Center","Rotterdam",{"type":40,"coordinates":66},[67,68],4.47917,51.9225,{"lat":68,"lon":67},[71],{"name":72,"role":25,"phone":73,"phoneExt":11,"email":11},"Robert Minnee, MD, PhD","+31107040704",{"type":75,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100499383","renal-ex-vivo-warm-advanced-resuscitation-through-machine-perfusion-100499383",false,"NCT05782543","Renal Ex Vivo Warm Advanced Resuscitation Through Machine Perfusion","Renal Ex Vivo Warm Advanced Resuscitation Through Machine Perfusion - The REWARM Study","REWARM","Inclusion Criteria:\n\n* Patients receiving their first or second kidney transplant;\n* Patients receiving a graft from a ≥ 50-year-old donor;\n* Patients receiving a graft from a DCD or DBD donor;\n* Patients receiving a kidney transplant in the UMCG, the Erasmus MC, or the LUMC;\n* Patients receiving a graft stored on HMP;\n* Patients ≥ 18 years of age;\n* Patients having provided written informed consent.\n\nExclusion Criteria:\n\n* Patients receiving their third or subsequent kidney transplant;\n* Patients receiving a graft from a donor \\\u003C 50 years;\n* Patients receiving a graft not stored on HMP;\n* Patients receiving a graft from a donor that underwent normothermic regional perfusion (NRP);\n* Patients receiving a kidney transplant in another center than the UMCG, Erasmus MC, or LUMC;\n* Patients receiving a multi-organ transplantation;\n* Patients receiving a kidney with complex arterial anatomy (3 or more arteries);\n* Recipients \\\u003C 18 years of age.","ALL","50 Years","100 Years",{"count":88,"type":89},240,"ESTIMATED","INTERVENTIONAL",[92],"NA","The REWARM study is a randomized controlled clinical efficacy study, with primary outcome renal function 12 months after transplantation of kidneys recovered from deceased donors aged 50 years or older. Prior to transplantation, kidney grafts in the intervention group will receive 6 hours of NMP, following standard HMP and kidneys in the control group will only receive standard treatment, being HMP. It is a multi-center trial. Given the total annual 50+ deceased donor kidney transplantation volume of the three participating transplant centers combined, inclusions in the study are expected to last 2.5-3 years, aiming for a total of 120 patients in each of the two arms (240 patients total).",[95],"Kidney Transplant; Complications","2025-12-10",{"date":98,"type":99},"2025-12-18","ACTUAL",{"date":101,"type":99},"2024-12-15",{"date":103,"type":89},"2028-05-01",{"name":5,"class":6},3]