[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553550":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":38,"responsibleParty":56,"collaborators":25,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":63,"acronym":25,"eligibilityCriteria":64,"healthyVolunteers":61,"sex":65,"minAge":66,"maxAge":25,"enrollmentInfo":67,"targetDuration":25,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":25,"overallStatus":41,"whyStopped":25,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Stanford University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Ergothioneine","EXPERIMENTAL","Ergothioneine (range 5 mg to 25 mg) oral daily for up to 12 weeks",[13],"Dietary Supplement: Ergothioneine",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Matching placebo oral daily for up to 12 weeks",[19],"Other: Placebo",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","Participants will receive ergothioneine capsule daily for 12 weeks.",[9],null,{"type":6,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Participants will receive placebo capsule daily for 12 weeks.",[15],[30],{"name":31,"affiliation":5,"role":32},"Tammy Sirich, MD","PRINCIPAL_INVESTIGATOR",[34],{"name":31,"role":35,"phone":36,"phoneExt":25,"email":37},"CONTACT","650-493-5000","tsirich@stanford.edu",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Veterans Affairs Palo Alto","RECRUITING","Palo Alto","California","94304","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-122.14302,37.44188,{"lat":51,"lon":50},[54],{"name":55,"role":35,"phone":36,"phoneExt":25,"email":37},"Tammy Sirich",{"type":32,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Tammy Lisa Sirich","Assistant Professor of Medicine","100553550","repletion-of-ergothioneine-in-patients-with-kidney-failure-100553550",false,"NCT06487546","Repletion of Ergothioneine in Patients With Kidney Failure","Inclusion Criteria:\n\n* kidney failure receiving hemodialysis or peritoneal dialysis\n\nExclusion Criteria:\n\n* blood transfusion within 90 days\n* taking supplements which contain ergothioneine","ALL","18 Years",{"count":68,"type":69},28,"ESTIMATED","INTERVENTIONAL",[72],"NA","Dialysis removes potentially harmful chemicals from the blood but can also remove potentially valuable chemicals. One potentially valuable chemical called ergothioneine, which comes from the diet, is low in the blood of people receiving dialysis. For this research study, the investigators hope to learn how well a daily ergothioneine supplement will replenish the levels in the blood of people with kidney failure.",[75],"Esrd","2026-03-26",{"date":78,"type":79},"2026-04-01","ACTUAL",{"date":81,"type":79},"2025-04-01",{"date":83,"type":69},"2030-12",{"name":5,"class":6},1]