[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584059":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":26,"locations":32,"responsibleParty":106,"collaborators":20,"id":108,"slug":109,"hasResults":110,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":20,"eligibilityCriteria":114,"healthyVolunteers":115,"sex":116,"minAge":117,"maxAge":118,"enrollmentInfo":119,"targetDuration":20,"studyType":122,"phases":123,"briefSummary":125,"conditions":126,"keywords":128,"overallStatus":71,"whyStopped":20,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":143},{"fullName":5,"class":6},"Mario Negri Institute for Pharmacological Research","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Healthy volunteers","EXPERIMENTAL","Healthy volunteers selected from 4 different centers. Each center will recruit 6 males and 6 females each.",[13],"Device: MRI",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","MRI","Multiparametric renal MRI on 1.5T scanners",[9],null,[22],{"name":23,"affiliation":24,"role":25},"Giuseppe Remuzzi, M.D.","Istituto Di Ricerche Farmacologiche Mario Negri","PRINCIPAL_INVESTIGATOR",[27],{"name":28,"role":29,"phone":30,"phoneExt":20,"email":31},"Matias Trillini, M.D.","CONTACT","+390354535411","matias.trillini@marionegri.it",[33,52,69,88],{"facility":34,"status":35,"city":36,"state":20,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Aarhus University Hospital","NOT_YET_RECRUITING","Aarhus","8200","Denmark","DK",{"type":41,"coordinates":42},"Point",[43,44],10.21076,56.15674,{"lat":44,"lon":43},[47,51],{"name":48,"role":29,"phone":49,"phoneExt":20,"email":50},"Niels H Buus, M.D.","+4530313404","nhb@biomed.au.dk",{"name":48,"role":25,"phone":20,"phoneExt":20,"email":20},{"facility":53,"status":35,"city":54,"state":20,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":62,"contacts":63},"University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University","Mannheim","68197","Germany","DE",{"type":41,"coordinates":59},[60,61],8.46694,49.4891,{"lat":61,"lon":60},[64,68],{"name":65,"role":29,"phone":66,"phoneExt":20,"email":67},"Dominik Nörenberg, MHBA","+4906213832067","Dominik.Noerenberg@medma.uni-heidelberg.de",{"name":65,"role":25,"phone":20,"phoneExt":20,"email":20},{"facility":70,"status":71,"city":72,"state":73,"zip":74,"country":75,"countryCode":76,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"IRCCS Azienda Ospedaliero-Universitaria di Bologna","RECRUITING","Bologna","BO","40138","Italy","IT",{"type":41,"coordinates":78},[79,80],11.33875,44.49381,{"lat":80,"lon":79},[83,87],{"name":84,"role":29,"phone":85,"phoneExt":20,"email":86},"Matteo Renzulli, M.D.","+390512141228","matteo.renzulli@aosp.bo.it",{"name":84,"role":25,"phone":20,"phoneExt":20,"email":20},{"facility":89,"status":35,"city":90,"state":91,"zip":92,"country":93,"countryCode":94,"cosmosGeoPoint":95,"geoPoint":99,"contacts":100},"Clínica Universidad de Navarra","Pamplona","Navarre","31008","Spain","ES",{"type":41,"coordinates":96},[97,98],-1.64323,42.81687,{"lat":98,"lon":97},[101,105],{"name":102,"role":29,"phone":103,"phoneExt":20,"email":104},"Nuria G Fernandez, M.D.","+34948255400","nrgarcia@unav.es",{"name":102,"role":25,"phone":20,"phoneExt":20,"email":20},{"type":107,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100584059","reproducibility-of-multiparametric-renal-magnetic-resonance-imaging-on-15t-mri-scanners-100584059",false,"NCT06884410","Reproducibility of Multiparametric Renal Magnetic Resonance Imaging on 1.5T MRI Scanners","Reproducibility of Multiparametric Renal Magnetic Resonance Imaging on 1.5T MRI Scanners (RESPECT_1.5T Sub-study)","Inclusion Criteria:\n\n* Provision of written informed consent prior to any study specific procedures\n* Male and female subjects aged \\[18-70\\] years\n* Office SBP values \\\u003C 140 mmHg and DBP values ≤ 90 mmHg, under no antihypertensive therapy\n* Normal renal function defined as: estimated glomerular filtration rate \\[eGFR\\] ≥ 60mL\u002Fmin\u002F1.73m2 (using CKD-EPI Creatinine Equation)\n* Negative result upon urine testing for haematuria or proteinuria.\n\nExclusion Criteria:\n\n* Previous enrollment in the present substudy\n* Contraindications to MRI including caustrophobia, pregnancy, cardiac pacemakers or other MRI-incompatible prostheses\n* Ongoing therapy (e.g. for diabetes, dyslipidemia, or any acute disease)\n* Past or current oncological pathology",true,"ALL","18 Years","70 Years",{"count":120,"type":121},48,"ESTIMATED","INTERVENTIONAL",[124],"NA","This is an interventional, multicenter, prospective study involving healthy volunteers, to primarily assess the reproducibility of multiparametric renal MRI on 1.5T scanners. The study is also aimed at assessing possible differences in renal MRI reproducibility on 1.5T MRI scanners by sex and age, and assessing possible differences in renal MRI reproducibility across field strengths (1.5T vs 3T) in the subgroup of subjects enrolled in both RESPECT clinical study and in the current subproject.",[127],"Multiparametric MRI",[129,130,131,132,133],"multiparametric MRI","standardization","reproducibility","kidney","MRI scanners","2025-08-29",{"date":136,"type":137},"2025-09-02","ACTUAL",{"date":139,"type":137},"2025-04-12",{"date":141,"type":121},"2026-04",{"name":5,"class":6},4]