[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100606466":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":14,"responsibleParty":29,"collaborators":7,"id":31,"slug":32,"hasResults":33,"nctId":34,"briefTitle":35,"officialTitle":36,"acronym":7,"eligibilityCriteria":37,"healthyVolunteers":33,"sex":38,"minAge":39,"maxAge":40,"enrollmentInfo":41,"targetDuration":7,"studyType":44,"phases":7,"briefSummary":45,"conditions":46,"keywords":7,"overallStatus":17,"whyStopped":7,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":57},{"fullName":5,"class":6},"Vertero Therapeutics","INDUSTRY",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"P.H.C. Kremer","CONTACT","+31 0715246400","clintrials@chdr.nl",[15],{"facility":16,"status":17,"city":18,"state":7,"zip":7,"country":19,"countryCode":20,"cosmosGeoPoint":21,"geoPoint":26,"contacts":27},"Center for Human Drug Research","RECRUITING","Leiden","Netherlands","NL",{"type":22,"coordinates":23},"Point",[24,25],4.49306,52.15833,{"lat":25,"lon":24},[28],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},{"type":30,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100606466","research-into-the-expression-of-the-csga-gene-and-how-it-changes-in-patients-with-parkinsons-disease-100606466",false,"NCT07175922","Research Into the Expression of the csgA-gene and How it Changes in Patients With Parkinson's Disease","Evaluation of csgA Prevalence, Gene Expression and Week-to-Week Variability in Participants With Parkinson's Disease and a History of Gastrointestinal Dysfunction","Inclusion Criteria:\n\n* Between 18-80 years of age at ICF signing (inclusive)\n* A diagnosis of PD within 10 years from the time of ICF signing\n* Current or history of gastrointestinal (GI) dysfunction or constipation based on screening assessment\n* All participants must understand and provide written informed consent prior to any study specific procedures\n* Able to speak, read, and understand study procedures in Dutch sufficiently to allow completion of all study assessments\n\nExclusion Criteria:\n\n* Any known GI disorder if deemed clinically significant by the investigator. GI disorders may include, but are not limited to: Crohn's disease, ulcerative colitis, celiac disease, irritable bowel syndrome, or lactose intolerance\n* Recent GI infection in the past 3 months if deemed clinically significant by the investigator.\n* Major GI surgery (excluding appendectomy\u002Fcholecystectomy), such as bariatric surgery, gastrectomy, esophagectomy, vagotomy, small intestine surgeries, any type of colectomy, colostomy and anorectal surgeries if deemed clinically significant by the investigator\n* Any known current or past eating disorder if deemed clinically significant by the investigator\n* Use of systemic antibiotics within 6 months prior to enrollment","ALL","18 Years","80 Years",{"count":42,"type":43},200,"ESTIMATED","OBSERVATIONAL","This study seeks to understand the prevalence and variability of a gut bacteria gene called csgA in people with Parkinson's Disease. This understanding could inform development of potential new therapies targeting the gut in Parkinson's Disease.",[47],"Parkinsons Disease (PD)","2026-02-16",{"date":50,"type":51},"2026-02-19","ACTUAL",{"date":53,"type":51},"2025-09-25",{"date":55,"type":43},"2026-03-30",{"name":5,"class":6},1]