[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599213":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":24,"locations":30,"responsibleParty":47,"collaborators":12,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":12,"eligibilityCriteria":56,"healthyVolunteers":53,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":12,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":33,"whyStopped":12,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Nanchang University Affiliated Rehabilitation Hospital","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Sham Stimulation Group","NO_INTERVENTION","Sham Stimulation Group received sham stimulation using device B, which had identical appearance, interface parameters, and physical sensation but no therapeutic effect. Stimulation parameters were set as follows: sinusoidal waveform; pulse width of 200μs; frequency of 20Hz; current adjusted to 0mA by the investigator; single session duration of 30 minutes. After each session, the device was disinfected with 75% alcohol. Treatment was administered once daily, 5 days per week, for a total duration of 4 weeks.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"transcutaneous auriculai vagus nerve stimulation","EXPERIMENTAL","The patient was positioned in a supine position. Two stimulating electrodes were placed on the bilateral concha cymba and concha cavum. Stimulation parameters were set as follows: sinusoidal waveform; pulse width of 200μs; frequency of 20Hz; initial intensity of 2mA. Each treatment session lasted 30 minutes. Treatment was administered once daily, 5 days per week, for a total duration of 4 weeks. After each treatment session, the device was disinfected with 75% alcohol.",[18],"Device: transcutaneous auriculai vagus nerve stimulation",[20],{"type":21,"name":14,"description":22,"armGroupLabels":23,"otherNames":12},"DEVICE","During bi-ear synchronous vagus nerve stimulation, the patient was positioned in a supine position. Two stimulating electrodes were placed bilaterally in the concha cymba and concha cavum of the ears. The patient received treatment for 30 minutes per session, once daily, 5 days per week, for a total of 4 weeks. Following each treatment session, the device was disinfected with 75% alcohol.",[14],[25],{"name":26,"role":27,"phone":28,"phoneExt":12,"email":29},"Han Jinjing Attending Physician","CONTACT","13672202061","515476321@qq.com",[31],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"The Fourth Affiliated Rehabilitation Hospital of Nanchang University","RECRUITING","Nanchang","Jiangxi","330009","China","CN",{"type":40,"coordinates":41},"Point",[42,43],115.85306,28.68396,{"lat":43,"lon":42},[46],{"name":26,"role":27,"phone":28,"phoneExt":12,"email":29},{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Wentao Zeng","Doctor of Medicine","100599213","research-on-binaural-synchronous-vagus-nerve-regulation-of-sensorimotor-disorders-after-cerebral-infarction-100599213",false,"NCT07081568","Research on Binaural Synchronous Vagus Nerve Regulation of Sensorimotor Disorders After Cerebral Infarction","Inclusion Criteria:\n\n* Patients with first-episode ischemic stroke within 7 to 14 days of onset;\n* Be over 18 years old;\n* The skin at the irritated area remains intact;\n* The informed consent form has been signed.\n\nExclusion Criteria:\n\n* Severe cognitive dysfunction (Mini-Mental State Examination≥19);\n* Peripheral limb movement limiting factors (fractures);\n* History of major neurological and mental disorders in the past;\n* Uncontrollable limb and facial muscle twitching, and spontaneous profuse sweating;\n* Intracranial shunt pumps, metal implants","ALL","18 Years","80 Years",{"count":61,"type":62},40,"ESTIMATED","INTERVENTIONAL",[65],"NA","The aim of this study is to determine the efficacy and safety of binaural synchronous vagus nerve regulation in the treatment of patients with sensory and motor dysfunction after cerebral infarction through a randomized controlled clinical study, and to provide high-quality evidence support for binaural synchronous vagus nerve regulation in the treatment of cerebral infarction.",[68],"Cerebral Infarction",[70,71,72,73],"Ischemic Stroke","Transcutaneous Auriculai Vagus Nerve Stimulation","Rehabilitation for Cerebral Infarction","Neuromodulation","2025-10-02",{"date":76,"type":77},"2025-10-07","ACTUAL",{"date":79,"type":77},"2025-06-25",{"date":81,"type":62},"2027-12-31",{"name":5,"class":6},1]