[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100523544":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":32,"centralContacts":36,"locations":46,"responsibleParty":63,"collaborators":10,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":69,"acronym":10,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":10,"maxAge":10,"enrollmentInfo":73,"targetDuration":10,"studyType":76,"phases":10,"briefSummary":77,"conditions":78,"keywords":10,"overallStatus":49,"whyStopped":10,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Zhujiang Hospital","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Non pregnant people with prediabetes or diabetes",null,"Non pregnancy meeting the diagnosis of prediabetes or diabetes.",[13],"Diagnostic Test: Oral Glucose Tolerance Test",{"label":15,"type":10,"description":16,"interventionNames":17},"Non pregnant people with normal glucose tolerance","Non pregnant population with normal Oral Glucose Tolerance Test results.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"pregnant people with gestational diabetes mellitus","Pregnant people who meet the diagnosis of gestational diabetes.",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"pregnant people with normal glucose tolerance","Pregnant people with normal Oral Glucose Tolerance Test results.",[13],[27],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":10},"DIAGNOSTIC_TEST","Oral Glucose Tolerance Test","Grouping based on detected oral glucose tolerance test results without any other intervention.",[15,9,19,23],[33],{"name":34,"affiliation":5,"role":35},"Hongwei Zhou, Professor","STUDY_CHAIR",[37,43],{"name":38,"role":39,"phone":40,"phoneExt":41,"email":42},"Nianyi Zeng","CONTACT","13928801657","+86","zengny1@i.smu.edu.cn",{"name":34,"role":39,"phone":44,"phoneExt":41,"email":45},"18688489622","hzhou@smu.edu.cn",[47],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Zhujiang Hospital of Southern Medical University","RECRUITING","Guangzhou","Guangdong","510000","China","CN",{"type":56,"coordinates":57},"Point",[58,59],113.25,23.11667,{"lat":59,"lon":58},[62],{"name":38,"role":39,"phone":40,"phoneExt":41,"email":42},{"type":64,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100523544","research-on-potential-biomarkers-of-prediabetes-and-diabetes-based-on-maldi-tof-ms-platform-100523544",false,"NCT06097065","Research on Potential Biomarkers of Prediabetes and Diabetes Based on MALDI-TOF MS Platform.","Inclusion Criteria:\n\n1. Inclusion criteria for cases:\n\n   Non pregnant people: the remaining fasting serum\u002Fplasma and urine samples of prediabetes\u002Fdiabetes patients (prediabetes: IFG: FPG 6.1-6.9mmol\u002FL, Blood glucose 2h after meal\\\u003C7.8mmol\u002FL（WHO）; IGT: FPG\\\u003C7.0mmol\u002FL, Blood glucose 2h after meal 7.8-11.1mmol\u002FL（WHO）; diabetes: Typical symptoms of diabetes, FPG \\>= 7.0mmol\u002FL or 75g OGTT 2h blood glucose \\>= 11.1mmol\u002FL).\n\n   Pregnant people: the remaining fasting serum\u002Fplasma and urine samples of gestational diabetes patients (75g OGTT test FPG \\>= 5.1mmol\u002FL or 1h blood glucose \\>= 10.0mmol\u002FL or 2h blood glucose \\>= 8.5mmol\u002FL（IADPSG; ADA)).\n2. Inclusion criteria of the controls were as follows:\n\nNon pregnant people: the remaining fasting serum\u002Fplasma and urine samples of normal population for glucose tolerance test (FPG 3.9-6.1mmol\u002FL,75g OGTT test 1h blood glucose 6.7-11.1mmol\u002FL,75g OGTT test 2h blood glucose 3.6-7.8mmol\u002FL).\n\nPregnant people: the remaining fasting serum\u002Fplasma and urine samples of people who do not meet the diagnostic criteria for gestational diabetes (3.9\\\u003C=75g OGTT test FPG\\\u003C5.1mmol\u002FL,6.7 \\\u003C= 1h blood glucose\\\u003C10.0mmol\u002FL,3.6\\\u003C=2h blood glucose\\\u003C8.5mmol\u002FL).\n\n\\-\n\nExclusion Criteria:\n\nCommon exclusion criteria for cases and control were as follows: The sample volume of serum\u002Fplasma\u002Furine is less than 300ul; Improper storage of samples or repeated freezing and thawing; The serum \u002Fplasma has obvious hemolysis, lipemia or jaundice.\n\n\\-",true,"ALL",{"count":74,"type":75},2860,"ESTIMATED","OBSERVATIONAL","Through the MALDI-TOF MS platform, explore the proteomics and peptidomics differences of fasting serum\u002Fplasma and urine between non pregnant people with normal glucose tolerance test and prediabetes \u002Fdiabetes patients, pregnant people with normal glucose tolerance test and pregnant diabetes patients respectively; To explore the role of its proteomics and peptidomics differences in the diagnosis of prediabetes and diabetes, and to establish a new method of differential diagnosis by using the omics data and key characteristic peaks to find potential new diagnostic markers.",[79,80,81,82],"Prediabetes","Diabetes Mellitus","Gestational Diabetes Mellitus","Proteomics","2023-10-18",{"date":85,"type":86},"2023-10-24","ACTUAL",{"date":88,"type":86},"2022-05-20",{"date":90,"type":75},"2026-12-31",{"name":5,"class":6},1]