[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629296":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":10,"centralContacts":23,"locations":10,"responsibleParty":30,"collaborators":10,"id":34,"slug":35,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":38,"acronym":10,"eligibilityCriteria":39,"healthyVolunteers":40,"sex":41,"minAge":42,"maxAge":43,"enrollmentInfo":44,"targetDuration":47,"studyType":48,"phases":10,"briefSummary":49,"conditions":50,"keywords":10,"overallStatus":53,"whyStopped":10,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":10},{"fullName":5,"class":6},"Children's Hospital of Chongqing Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ASD group",null,"Inclusion criteria:\n\nDiagnosed by two or more associate chief physicians using the DSM-5 diagnostic criteria.\n\nParticipants aged between 18 and 60 months. Participants with a vocabulary size ranging from 0 to 50 words, as assessed using the Chinese Communicative Development Inventory.\n\nParticipants whose native language is Chinese.\n\nExclusion criteria:\n\nParticipants not meeting the age requirement. Presence of orofacial motor and swallowing dysfunction. Hearing impairment. Participants whose native language isn't Chinese. Neurological disorders (such as encephalitis or seizures) and comorbid psychiatric disorders.",[13],"Behavioral: Approaches to ASD social intervention",{"label":15,"type":10,"description":16,"interventionNames":10},"TD group","Inclusion Criteria:\n\nDiagnosed as typically developing children by two or more associate chief physicians.\n\nGender- and age-matched to the ASD group. Participants whose native language is Chinese.\n\nExclusion Criteria:\n\nParticipants not meeting the age requirement. Presence of orofacial motor and swallowing dysfunction. Hearing impairment. Participants whose native language isn't Chinese. Neurological disorders (such as encephalitis or seizures) and comorbid psychiatric disorders.",[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"BEHAVIORAL","Approaches to ASD social intervention","The intervention methods for children in the ASD group will be documented in detail (through telephone or online follow-ups, based on parental reports, with records including the location, time, frequency, and main content of the interventions); children in the TD group did not receive any intervention.",[9],[24],{"name":25,"role":26,"phone":27,"phoneExt":28,"email":29},"Li Chen, Doctor","CONTACT","13677620103","+86","chenli@cqmu.edu.cn",{"type":31,"investigatorFullName":32,"investigatorTitle":33,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Chen Li","Professor, Director","100629296","research-on-speech-development-trajectories-and-predictive-models-in-children-with-autism-spectrum-disorder-100629296",false,"NCT07472829","Research on Speech Development Trajectories and Predictive Models in Children With Autism Spectrum Disorder","Inclusion Criteria:\n\n* Diagnosed as typically developing children by two or more associate chief physicians.\n* Gender- and age-matched to the ASD group.\n* Participants whose native language is Chinese.\n\nExclusion Criteria:\n\n* Participants not meeting the age requirement.\n* Presence of orofacial motor and swallowing dysfunction.\n* Hearing impairment.\n* Participants whose native language isn't Chinese.\n* Neurological disorders (such as encephalitis or seizures) and comorbid psychiatric disorders.",true,"ALL","18 Months","60 Months",{"count":45,"type":46},120,"ESTIMATED","3 Months","OBSERVATIONAL","Recent studies indicate that children with ASD have a significantly higher risk of co-occurring speech sound disorders than typically developing children. Early atypical speech development may be a critical yet overlooked bottleneck hindering their language improvement. Given the unique phonetic features of Mandarin, it is essential to investigate speech development in Mandarin-speaking children with ASD. This study aims to construct developmental trajectories and establish early identification and prognosis prediction models for this population.",[51,52],"Speech","Autism Spectrum Disorder (ASD)","NOT_YET_RECRUITING","2026-03-14",{"date":56,"type":57},"2026-03-17","ACTUAL",{"date":59,"type":46},"2026-03-10",{"date":61,"type":46},"2027-12-31",{"name":5,"class":6}]