[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100603608":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":31,"responsibleParty":49,"collaborators":53,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":59,"acronym":20,"eligibilityCriteria":60,"healthyVolunteers":57,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":20,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":33,"whyStopped":20,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Peking Union Medical College Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"68Ga-FAPI PET\u002FCT& 99mTc-CTR-FAPI SPECT","EXPERIMENTAL","All enrolled patients will undergo one 99mTc-CTR-FAPI SPECT scan and one 68Ga-FAPI PET\u002FCT scan within a 1-week interval.",[13],"Diagnostic Test: 68Ga-FAPI PET\u002FCT and 99mTc-CTR-FAPI SPECT",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","68Ga-FAPI PET\u002FCT and 99mTc-CTR-FAPI SPECT","For 68Ga-FAPI PET\u002FCT scan，each patient was injected with 1.8-2.2 MBq\u002Fkg (0.05-0.06 mCi\u002Fkg) body weight of 68Ga-FAPI. PET\u002FCT from skull to feet was performed 60±5 min post-injection.\n\nFor 99mTc-CTR-FAPI SPECT scan:each patient was injected with 10-20mCi 99mTc-CTR-FAPI . Planar SPECT scan and SPECT\u002FCT were performed 60±5 min post-injection.",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Yaping LUO","PRINCIPAL_INVESTIGATOR",[26],{"name":27,"role":28,"phone":29,"phoneExt":20,"email":30},"Yaping Luo, MD","CONTACT","86-010-69154716","luoyaping@live.com",[32],{"facility":5,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"RECRUITING","Beijing","Beijing Municipality","100730","China","CN",{"type":40,"coordinates":41},"Point",[42,43],116.39723,39.9075,{"lat":43,"lon":42},[46],{"name":47,"role":28,"phone":48,"phoneExt":20,"email":20},"Jiayue Li","010-69156874",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"SPONSOR_INVESTIGATOR","Luo Yaping","Medical Doctor (M.D.), Chief Physician, Professor, Assistant Director",[54],{"name":5,"class":6},"100603608","research-on-the-application-of-99mtc-tcr-fapi-spect-imaging-in-rheumatoid-arthritis-100603608",false,"NCT07138729","Research on the Application of 99mTc-TCR-FAPI SPECT Imaging in Rheumatoid Arthritis","Inclusion Criteria:\n\n1. Age: 18-75 years old;\n2. Meet the classification criteria for rheumatoid arthritis of the American College of Rheumatology\u002FEuropean Union for Rheumatology in 2010;\n3. The highest disease activity in clinical practice (CDAI or SDAI score\n\nExclusion Criteria:\n\n1. Patients with other autoimmune diseases;\n2. Patients with concurrent tumors;\n3. Women who are pregnant or planning to become pregnant, women in the preconception period, pregnant and lactating women, and women with child-rearing plans during the study period; Subjects of childbearing age need to take effective contraceptive measures during the research process;\n4. Active infection\n5. Suffering from claustrophobia or other mental disorders, with poor compliance resulting in inability to cooperate with this researcher; (6) Situations where other researchers consider it inappropriate to participate in this clinical trial.","ALL","18 Years","75 Years",{"count":65,"type":66},20,"ESTIMATED","INTERVENTIONAL",[69],"NA","This study proposes to evaluate 99mTc-CTR-FAPI SPECT imaging as a cost-effective, low-radiation, and widely accessible alternative to 68Ga-FAPI PET\u002FCT for assessing synovial lesions in RA patients, aiming to validate its diagnostic consistency with both PET\u002FCT and physical examinations while correlating imaging findings with clinical disease activity metrics to establish a practical tool for long-term RA monitoring.",[72],"Rheumatoid Arthritis (RA)",[74,75,76],"Rheumatoid arthritis","68Ga-FAPI PET \u002F CT","99mTc-CTR-FAPI SPECT","2025-08-22",{"date":79,"type":80},"2025-08-24","ACTUAL",{"date":82,"type":80},"2025-05-10",{"date":84,"type":66},"2028-04-28",{"name":51,"class":6},1]