[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613821":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":35,"responsibleParty":50,"collaborators":11,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":11,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":11,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":11,"overallStatus":38,"whyStopped":11,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Second Affiliated Hospital, School of Medicine, Zhejiang University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Phycocyanin Intervention","EXPERIMENTAL",null,[13],"Dietary Supplement: phycocyanin",{"label":15,"type":16,"description":11,"interventionNames":17},"Maltodextrin Placebo","PLACEBO_COMPARATOR",[18],"Other: Maltodextrin (Placebo)",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"DIETARY_SUPPLEMENT","phycocyanin","Oral phycocyanin formulation treatment, 1.5g\u002Fday, for at least 4 weeks (The phycocyanin was provided free of charge by Inner Mongolia Zaihui Shou Bio-engineering Co., Ltd., with company production license number SC12215062400192, executive standard GB 1886.309-2020, food-grade specifications, and batch number E4020250324. All samples used in the clinical study are from the same batch, packaged in opaque aluminum composite bags, 1.5g\u002Fbag, and stored frozen).",[9],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Maltodextrin (Placebo)","This is the placebo control group. The patients will receive the same dosage of maltodextrin for at least 4 weeks.",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"Xiaopeng Cai","CONTACT","+86 18768161626","cxpeng@zju.edu.cn",[36],{"facility":37,"status":38,"city":39,"state":11,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"The Second Affiliated Hospital of Zhejiang University","RECRUITING","Hangzhou","China","CN",{"type":43,"coordinates":44},"Point",[45,46],120.16142,30.29365,{"lat":46,"lon":45},[49],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},{"type":51,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100613821","research-on-the-protective-effects-of-phycocyanin-against-liver-fibrosis-and-cirrhosis-100613821",false,"NCT07271576","Research on the Protective Effects of Phycocyanin Against Liver Fibrosis and Cirrhosis","Research on the Role of Phycocyanin in the Prevention, Treatment, and Mechanism of Liver Fibrosis\u002FCirrhosis","Inclusion Criteria:\n\n* Adults between the ages of 18 and 75;\n* Patients diagnosed with liver fibrosis or cirrhosis;\n* Voluntary participation in this study and signing of an informed consent form;\n* No acute diseases or significantly worsening symptoms for at least 4 weeks prior to enrollment.\n\nExclusion Criteria:\n\n* Presence of severe comorbidities;\n* Allergy to phycocyanin;\n* Patients with a history of severe mental illness that may affect treatment compliance.","ALL","18 Years","75 Years",{"count":63,"type":64},10,"ESTIMATED","INTERVENTIONAL",[67],"NA","This clinical trial aims to determine whether phycocyanin, a natural protein derived from spirulina, can help treat liver fibrosis or cirrhosis in adult patients. The main questions it aims to answer are:\n\n* Can phycocyanin reduce blood levels of liver enzymes (such as ALT and AST) that indicate liver damage?\n* Can phycocyanin improve liver stiffness as measured by ultrasound?\n\nResearchers will compare the phycocyanin intervention group with a control group that receives a placebo (a similar-looking maltodextrin supplement without active ingredients) to explore if phycocyanin is more effective in treating liver fibrosis\u002Fcirrhosis.\n\nParticipants will:\n\n* Take one sachet of either phycocyanin or placebo daily for at least 4 weeks.\n* Attend regular clinic appointments (typically every 2-3 months) for routine monitoring of your liver condition, which will include blood and urine tests.\n* Provide blood and stool samples once before the treatment and once after the 4-week treatment period.\n* Undergo an ultrasound evaluation of liver stiffness.\n\nThe study will last approximately 2 years, and the personal information of all patients will be kept strictly confidential.",[70,71],"Liver Fibrosis","Liver Cirrhosis","2025-12-07",{"date":74,"type":75},"2025-12-09","ACTUAL",{"date":77,"type":75},"2025-06-04",{"date":79,"type":64},"2027-06-04",{"name":5,"class":6},1]