[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599103":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":53,"centralContacts":57,"locations":10,"responsibleParty":65,"collaborators":10,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":10,"eligibilityCriteria":72,"healthyVolunteers":69,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":10,"studyType":79,"phases":10,"briefSummary":80,"conditions":81,"keywords":10,"overallStatus":84,"whyStopped":10,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":10},{"fullName":5,"class":6},"Shanxi Bethune Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group INSTI",null,"Treated by INSTI",[13],"Drug: All kinds of INSTI medications",{"label":15,"type":10,"description":16,"interventionNames":17},"Group CONV","Treated by Conventional medicines",[18],"Drug: All kinds of conventional medications",[20,39],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","All kinds of INSTI medications","All kinds of INSTI medications, such as Bictegravir\u002FEmtricitabine\u002FTenofovir alafenamide Fumarate, Dolutegravir\u002FEmtricitabine\u002FTenofovir alafenamide Fumarate for PLWH",[9],[26,27,28,29,30,31,32,33,34,35,36,37,38],"Bictegravir\u002FEmtricitabine\u002FTenofovir alafenamide Fumarate","Dolutegravir\u002FEmtricitabine\u002FTenofovir alafenamide Fumarate","Abacavir\u002FDolutegravir\u002FLamivudine","Albuvirtide","Dolutegravir","Dolutegravir\u002FLamivudine","Elvitegravir\u002FCobicistat\u002FEmtricitabine\u002FTenofovir alafenamide Fumarate","Emtricitabine\u002FTenofovir","Emtricitabine\u002FTenofovir alafenamide Fumarate","Enovirin","Lamivudine\u002FZidovudine","Raltegravir","Rilpivirine",{"type":21,"name":40,"description":41,"armGroupLabels":42,"otherNames":43},"All kinds of conventional medications","All kinds of conventional medications, such as Abacavir, Efavirenz for PLWH",[15],[44,45,46,47,48,49,50,51,52],"Abacavir","Efavirenz","Emtricitabine","Lamivudine","Lopinavir\u002FRitonavir","Nevirapine","Tenofovir","Tenofovir alafenamide Fumarate","Zidovudine",[54],{"name":55,"affiliation":5,"role":56},"Xingyu Li, doctor","PRINCIPAL_INVESTIGATOR",[58,63],{"name":59,"role":60,"phone":61,"phoneExt":10,"email":62},"Yan Wang, Doctor","CONTACT","13513635015","wangyaner7711@163.com",{"name":64,"role":60,"phone":10,"phoneExt":10,"email":10},"Junyan Zhang, doctor",{"type":66,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100599103","research-on-the-psychological-status-of-patients-with-hiv-1-infection-100599103",false,"NCT07080138","Research on the Psychological Status of Patients With HIV-1 Infection","Inclusion Criteria:\n\n1. Diagnosis: PLWH can be diagnosed if one of the following three items is met according to the Chinese AIDS Diagnosis and Treatment Guidelines (2021):\n\n   ① HIV antibody screening test positive and HIV supplementation test positive (antibody supplementation test positive or nucleic acid qualitative test positive or nucleic acid quantification\\>5000 copies\u002FmL);\n\n   ② Has a history of epidemiology or clinical manifestations related to AIDS, tested positive for HIV nucleic acid twice;\n\n   ③ HIV isolation test positive;\n2. Receive treatment at the hospital participating in the study; Age range: 18-80 years old, male or female not limited;\n3. Patients who are willing to participate in this clinical study and sign the informed consent form for this study.\n\nExclusion Criteria:\n\nIndividuals who meet any of the following criteria are not eligible to participate in this study:\n\n1. Pregnant or lactating women; Men and women who are preparing for natural conception or artificial assisted reproduction;\n2. Severe aphasia, physical disability, or any other non neuropsychological factors that may hinder the completion of the assessment;\n3. is currently involved in other research;\n4. Having a tendency towards violence may endanger the safety of others.","ALL","18 Years","80 Years",{"count":77,"type":78},500,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to investigate the neuropsychological states of People Living With HIV(PLWH), the prevalence of social and psychological stress adaptation overload and poor episodic memory in PLWH. The main questions it aims to observe are: to observe the prevalence of psychopathic states in PLWH with different viral loads and to compare the effects of different treatments on the prevalence of psychopathic states in PLWH. It is helpful to understand the mental health burden faced by PLWH in China, to improve clinicians' awareness of PLWH's mental and psychological state, and formulate targeted psychological support, treatment and nursing programs.",[82,83],"HIV-1-infection","Anxiety Depression","NOT_YET_RECRUITING","2025-07-14",{"date":87,"type":88},"2025-07-23","ACTUAL",{"date":90,"type":78},"2025-08-01",{"date":92,"type":78},"2026-12-31",{"name":5,"class":6}]