[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595447":3},{"organization":4,"armGroups":7,"interventions":78,"overallOfficials":101,"centralContacts":105,"locations":110,"responsibleParty":124,"collaborators":127,"id":131,"slug":132,"hasResults":133,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":84,"eligibilityCriteria":137,"healthyVolunteers":133,"sex":138,"minAge":139,"maxAge":84,"enrollmentInfo":140,"targetDuration":84,"studyType":143,"phases":144,"briefSummary":146,"conditions":147,"keywords":153,"overallStatus":183,"whyStopped":84,"lastUpdateSubmitDate":184,"lastUpdatePostDateStruct":185,"startDateStruct":188,"completionDateStruct":190,"leadSponsor":192,"locationsCount":193},{"fullName":5,"class":6},"Stanford University","OTHER",[8,14,19,24,28,33,37,41,45,50,54,58,62,66,70,74],{"label":9,"type":10,"description":11,"interventionNames":12},"Condition 1","EXPERIMENTAL","Core Only",[13],"Behavioral: Core Behavioral Weight Loss Intervention",{"label":15,"type":10,"description":16,"interventionNames":17},"Condition 2","Core + Increase Fiber",[13,18],"Behavioral: Increase Fiber Intake",{"label":20,"type":10,"description":21,"interventionNames":22},"Condition 3","Core + Increase Protein",[13,23],"Behavioral: Increase Protein",{"label":25,"type":10,"description":26,"interventionNames":27},"Condition 4","Core + Increase Protein + Increase Fiber",[13,23,18],{"label":29,"type":10,"description":30,"interventionNames":31},"Condition 5","Core + Limit Eating Window",[13,32],"Behavioral: Limit Eating Window",{"label":34,"type":10,"description":35,"interventionNames":36},"Condition 6","Core + Limit Eating Window + Increase Fiber",[13,32,18],{"label":38,"type":10,"description":39,"interventionNames":40},"Condition 7","Core + Limit Eating Window + Increase Protein",[13,32,23],{"label":42,"type":10,"description":43,"interventionNames":44},"Condition 8","Core + Limit Eating Window + Increase Protein + Increase Fiber",[13,32,23,18],{"label":46,"type":10,"description":47,"interventionNames":48},"Condition 9","Core + Limit Red Zone Foods",[13,49],"Behavioral: Limit Red Zone Foods",{"label":51,"type":10,"description":52,"interventionNames":53},"Condition 10","Core + Limit Red Zone Foods + Increase Fiber",[13,49,18],{"label":55,"type":10,"description":56,"interventionNames":57},"Condition 11","Core + Limit Red Zone Foods + Increase Protein",[13,49,23],{"label":59,"type":10,"description":60,"interventionNames":61},"Condition 12","Core + Limit Red Zone Foods + Increase Protein + Increase Fiber",[13,49,23,18],{"label":63,"type":10,"description":64,"interventionNames":65},"Condition 13","Core + Limit Red Zone Foods + Limit Eating Window",[13,49,32],{"label":67,"type":10,"description":68,"interventionNames":69},"Condition 14","Core + Limit Red Zone Foods + Limit Eating Window + Increase Fiber",[13,49,32,18],{"label":71,"type":10,"description":72,"interventionNames":73},"Condition 15","Core + Limit Red Zone Foods + Limit Eating Window + Increase Protein",[13,49,32,23],{"label":75,"type":10,"description":76,"interventionNames":77},"Condition 16","Core + Limit Red Zone Foods + Limit Eating Window + Increase Protein + Increase Fiber",[13,49,32,23,18],[79,85,89,93,97],{"type":80,"name":81,"description":82,"armGroupLabels":83,"otherNames":84},"BEHAVIORAL","Core Behavioral Weight Loss Intervention","All participants receive a 12-week core behavioral weight loss intervention consisting of the following: daily self-monitoring of weight; weekly behavioral lessons and action plans to promote healthy eating and physical activity; and tailored feedback. The intervention will be delivered remotely via email and\u002For text message.",[9,51,55,59,63,67,71,75,15,20,25,29,34,38,42,46],null,{"type":80,"name":86,"description":87,"armGroupLabels":88,"otherNames":84},"Limit Red Zone Foods","Participants randomized to receive this component are given a goal to limit their Red Zone Foods (i.e., foods high in calories and low in nutrition) and are instructed to self-monitor them daily.",[51,55,59,63,67,71,75,46],{"type":80,"name":90,"description":91,"armGroupLabels":92,"otherNames":84},"Limit Eating Window","Participants randomized to receive this component are given a goal to limit their eating windows (i.e., follow time-restricted eating) and are instructed to self-monitor them daily.",[63,67,71,75,29,34,38,42],{"type":80,"name":94,"description":95,"armGroupLabels":96,"otherNames":84},"Increase Protein","Participants randomized to receive this component are given a goal to increase their protein intake and are instructed to self-monitor it daily.",[55,59,71,75,20,25,38,42],{"type":80,"name":98,"description":99,"armGroupLabels":100,"otherNames":84},"Increase Fiber Intake","Participants randomized to receive this component are given a goal to increase their fiber intake and are instructed to self-monitor it daily.",[51,59,67,75,15,25,34,42],[102],{"name":103,"affiliation":5,"role":104},"Michele L Patel, PhD","PRINCIPAL_INVESTIGATOR",[106],{"name":103,"role":107,"phone":108,"phoneExt":84,"email":109},"CONTACT","650-549-7047","ResetStudy@stanford.edu",[111],{"facility":112,"status":84,"city":113,"state":114,"zip":115,"country":116,"countryCode":117,"cosmosGeoPoint":118,"geoPoint":123,"contacts":84},"Stanford University School of Medicine","Palo Alto","California","94304","United States","US",{"type":119,"coordinates":120},"Point",[121,122],-122.14302,37.44188,{"lat":122,"lon":121},{"type":104,"investigatorFullName":125,"investigatorTitle":126,"investigatorAffiliation":5,"oldNameTitle":84,"oldOrganization":84},"Michele Patel","Principal Investigator",[128],{"name":129,"class":130},"Stanford Nutrition and Obesity Research Center","UNKNOWN","100595447","reset-enhancing-weight-loss-in-a-digital-intervention-100595447",false,"NCT07032571","Reset: Enhancing Weight Loss in a Digital Intervention","Enhancing Weight Loss in a Digital Intervention Among Adults With Overweight or Obesity","Inclusion Criteria:\n\n* adults (ages 18+ years)\n* body mass index (BMI) 25.0 to 45.0 kg\u002Fm\\^2\n* cellphone ownership with a texting plan\n* daily access to a personal scale\n* daily access to a personal email account\n* English language proficiency\n* interest in losing weight through behavioral strategies\n* living in the United States\n\nExclusion Criteria:\n\n* concurrent enrollment in another weight management intervention\n* loss of ≥5% body weight in the past 6 months\n* current use of a weight loss or anti-obesity medication\n* prior or planned bariatric surgery in the next 3 months\n* current pregnancy, planned pregnancy in the next 3 months, or recent pregnancy in the past 6 months\n* current breastfeeding or lactating\n* living with someone else participating in the study\n* hospitalization for a mental health condition in the past 12 months\n* inability to engage in moderate forms of physical activity akin to brisk walking\n* if weight loss is contraindicated or might be impacted by a condition (e.g., end stage renal disease, cancer, schizophrenia, dementia) or medication (e.g., steroids, antipsychotics)\n* if an individual would be better suited for a more intensive or different type of intervention based on a health condition (e.g., individuals with history of an eating disorder or cardiovascular event, uncontrolled hypertension, or uncontrolled diabetes mellitus)\n* participation in another weight loss study conducted in Dr. Patel's lab in the past 6 months\n* investigator discretion for safety reasons","ALL","18 Years",{"count":141,"type":142},208,"ESTIMATED","INTERVENTIONAL",[145],"NA","The goal of the Reset trial is to learn about the optimal combination of dietary behavior strategies in a fully digital weight loss intervention. The intervention is designed for adults with overweight or obesity. The investigators will examine the impact on weight loss of four dietary strategies: 1) limiting Red Zone Foods (i.e., foods that are high in calories and low in nutrition), 2) limiting eating windows, 3) increasing protein intake, and 4) increasing fiber intake. Each of these strategies will include goal setting, daily self-monitoring, and tailored feedback.\n\nThe investigators will recruit 208 participants. Broadly, adults with overweight or obesity who live in the U.S. will be eligible. The weight loss intervention will last 12 weeks. All participants will be asked to track their body weight daily and complete weekly behavioral lessons and action plans to promote healthy eating and physical activity. All study tasks will occur remotely. Assessment of body weight and survey measures will occur at the beginning of the trial (\"baseline\"), and at 1 month and 3 months.\n\nThe Multiphase Optimization Strategy (MOST) framework will be used to identify which combination of the dietary behavior strategies results in the greatest weight loss. In total, there will be 16 treatment conditions.",[148,149,150,151,152],"Obesity","Overweight","Weight Loss","Health Behavior","Lifestyle Intervention",[154,155,156,157,158,159,160,161,162,163,164,165,166,167,168,169,170,171,172,173,174,175,176,177,178,179,180,181,182],"obesity","overweight","weight loss","weight","health behavior","lifestyle intervention","lifestyle modification","multiphase optimization strategy","intervention","behavior change","weight reduction","lose weight","adults","BMI reduction","body fat reduction","weight control","weight change","weight management","obesity management","obesity treatment","digital health","digital intervention","remote intervention","standalone intervention","obesity prevention","diabetes prevention","mobile health","factorial design","intervention optimization","NOT_YET_RECRUITING","2026-02-28",{"date":186,"type":187},"2026-03-03","ACTUAL",{"date":189,"type":142},"2026-04",{"date":191,"type":142},"2026-08",{"name":5,"class":6},1]