[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100567548":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":44,"responsibleParty":58,"collaborators":60,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":67,"sex":73,"minAge":74,"maxAge":25,"enrollmentInfo":75,"targetDuration":25,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":88,"overallStatus":47,"whyStopped":25,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"University of North Carolina, Chapel Hill","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ABC Program - no wait","EXPERIMENTAL","Participants immediately receive the home-based ABC, which targets parenting sensitivity and nurturance.",[13],"Behavioral: Attachment and Biobehavioral Catch-up (ABC)",{"label":15,"type":6,"description":16,"interventionNames":17},"Waitlist-Control (ABC after delay)","Participants will be placed on a four-month waitlist and then receive ABC in the same manner as the Experimental Group",[13,18],"Other: Waitlist with 4-month delay, then ABC",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Attachment and Biobehavioral Catch-up (ABC)","10-session home visiting intervention designed to increase parental sensitivity and nurturance and decrease parental frightening behavior.",[9,15],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Waitlist with 4-month delay, then ABC","A 4-month waitlist period, after which they will also receive the home-based ABC program (same as Intervention group).",[15],[31],{"name":32,"affiliation":5,"role":33},"Danielle Roubinov, PhD","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Danielle Rouvinov, PhD","CONTACT","919-843-5898","roubinov@email.unc.edu",{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},"Nicole Bush, PhD","415-476-7655","Nicole.Bush@ucsf.edu",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":25,"geoPoint":25,"contacts":53},"University of North Carolina at Chapel Hill","RECRUITING","Chapel Hill","South Carolina","27599","United States","US",[54],{"name":55,"role":37,"phone":56,"phoneExt":25,"email":57},"Natalie O'Brien","919-966-0421","natalie_obrien@med.unc.edu",{"type":59,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[61,63],{"name":62,"class":6},"University of California, San Francisco",{"name":64,"class":6},"The Duke Endowment","100567548","resilience-through-interventions-for-successful-early-outcomes-100567548",false,"NCT06669624","Resilience Through Interventions for Successful Early Outcomes","Leveraging Scientific Advances to Strengthen the Implementation, Evaluation, and Impacts of Intervention Programs for Children Experiencing Early Life Adversity","RISE","Parent\u002FCaregiver Inclusion Criteria :\n\n* Aged 18 or older\n* Speaks English or Spanish\n* Is the parent or legal guardian with legal custody of a child aged between 24 months and 42 months\n* Is a primary caregiver\u002Fparent\n* Has a home-like environment in which to participate in the intervention\n\nChild Inclusion Criteria:\n\n* Aged between 24 months and 42 months at enrollment\n* Lives with the parent\u002Fcaregiver at least 50% of the time\n* Has experienced social risk factors, including low income, community or family violence, previous trauma\u002Fadversity exposure, prolonged separation from caregiver, significant difficulties in relationship with caregiver Child Exclusion Criteria\n* Has a diagnosed genetic or congenital disorders, including but not limited to Down syndrome, cerebral palsy, seizure disorders, endocrine disorders (or is using steroid medications, including human growth hormone), or was born with birth defects","ALL","18 Years",{"count":76,"type":77},150,"ESTIMATED","INTERVENTIONAL",[80],"NA","Purpose: The purpose of this research is to determine the effects of Attachment and Biobehavioral Catch-up (ABC), an evidence-based parenting program, on stress biomarkers in children.\n\nParticipants: The study will involve approximately 150 caregiver-child dyads, with children aged between 24 and 42 months. Participants will include primary caregivers fluent in English or Spanish, along with their children who have experienced social risk factors for adversity.\n\nProcedures (Methods): Participants will be randomly assigned to either receive the ABC parenting program (10 sessions) immediately or be placed on a wait-list, receiving the program after about 4 months. The study procedures include caregivers completing online surveys, engaging in play-based observational tasks with their children, and collecting non-invasive biological samples (saliva, cheek swab, hair) from the children and saliva samples from the caregivers at 2-3 time-points.",[83,84,85,86,87],"Parenting Intervention","Stress","Caregiver Child Relationship","Child Behavior Problem","Mental Health",[89,83,90,91,92],"Attachment and Biobehavioral CatchUp","RISE study","Child behavior","Biomarkers","2026-01-30",{"date":95,"type":96},"2026-02-02","ACTUAL",{"date":98,"type":96},"2024-11-12",{"date":100,"type":77},"2027-08",{"name":5,"class":6},1]