[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100591020":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":17,"centralContacts":29,"locations":35,"responsibleParty":60,"collaborators":63,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":69,"sex":75,"minAge":76,"maxAge":17,"enrollmentInfo":77,"targetDuration":17,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":38,"whyStopped":17,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Turku University Hospital","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Synbiotic","ACTIVE_COMPARATOR","Bifidobacterium bifidum and human milk oligosaccharides (HMOs)",[13],"Dietary Supplement: Synbiotic Supplement",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR",null,[19],"Other: Placebo",[21,25],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":17},"DIETARY_SUPPLEMENT","Synbiotic Supplement",[9],{"type":26,"name":15,"description":27,"armGroupLabels":28,"otherNames":17},"OTHER","Maltodextrin",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":17,"email":34},"Paula Tähtinen, MD, PhD","CONTACT","+358-2-3130746","paula.tahtinen@utu.fi",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Department of Paediatrics and Adolescent Medicine, Turku University Hospital and University of Turku","RECRUITING","Turku","Valitse Maakunta.","20780","Finland","FI",{"type":45,"coordinates":46},"Point",[47,48],22.26869,60.45148,{"lat":48,"lon":47},[51,52,53,56,58],{"name":31,"role":32,"phone":33,"phoneExt":17,"email":34},{"name":17,"role":32,"phone":17,"phoneExt":17,"email":34},{"name":54,"role":55,"phone":17,"phoneExt":17,"email":17},"Erika Isolauri, MD, PhD","PRINCIPAL_INVESTIGATOR",{"name":31,"role":57,"phone":17,"phoneExt":17,"email":17},"SUB_INVESTIGATOR",{"name":59,"role":57,"phone":17,"phoneExt":17,"email":17},"Tuuli Vuorisalo, MD",{"type":55,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":17,"oldOrganization":17},"Erika Isolauri","Professor of Paediatrics",[64],{"name":65,"class":66},"Lallemand Health Solutions","INDUSTRY","100591020","resilience-to-antibiotic-induced-obesogenic-microbiota-discovering-mechanism-of-microbiota-modulation-100591020",false,"NCT06974994","Resilience to Antibiotic-induced Obesogenic Microbiota: Discovering Mechanism of Microbiota Modulation","Resilience to Antibiotic-induced Obesogenic Microbiota Vertically Transferred to the Neonatal Gut: Discovering Mechanism of Microbiota Modulation","ReCoverHealth","Inclusion Criteria:\n\nPregnant women (n=125) and their newborn children who receive antibiotic treatment at delivery.\n\nExclusion Criteria:\n\n* Chorioamnionitis\n* Pre-eclampsia and hepatogestosis\n* Suspected malformation or serious condition of the foetus and neonates\n* Serious infection or other conditions not permitting breast milk feeding","ALL","2 Hours",{"count":78,"type":79},125,"ESTIMATED","INTERVENTIONAL",[82],"NA","The aim is to study whether the microbiota of children who are exposed to antibiotics at birth could be modified by synbiotic supplement and thereby reduce the risk of obesity, chronic diseases and respiratory tract infections. A total of 125 mother-child pairs will be recruited in this randomized, double-blind, placebo-controlled study. Infants are randomized to receive either a synbiotic supplement or a placebo for 2 months, after which their growth and morbidity will be monitored at the research clinic for 2 years.",[85],"Healthy Newborn Infants",[87,88,89,90,91,92,93,94],"antibiotics","human milk oligosaccharides","probiotics","newborn","microbiome","microbiota","obesity","infectious diseases","2025-05-07",{"date":97,"type":98},"2025-05-16","ACTUAL",{"date":100,"type":98},"2024-05-08",{"date":102,"type":79},"2029-12",{"name":5,"class":6},1]