[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100444880":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":16,"locations":26,"responsibleParty":47,"collaborators":50,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":10,"studyType":73,"phases":10,"briefSummary":74,"conditions":75,"keywords":77,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Penn State University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Children with healthy weight status",null,"100 child-parent dyads (200 total) will be followed for 1 year to determine the behavioral and neural impact of food and toy advertising exposure. Children will be 7-9 years old, with body mass index \\\u003C 85th % for age and sex, and either with a mother who has BMI of 30 kg\u002Fm-sq or over or a BMI of 25 kg\u002Fm-sq or less.",[13],{"name":14,"affiliation":5,"role":15},"Kathleen L Keller, Ph.D.","PRINCIPAL_INVESTIGATOR",[17,22],{"name":18,"role":19,"phone":20,"phoneExt":10,"email":21},"Kyle M Hallisky, B.S.","CONTACT","814-865-5169","kmh6587@psu.edu",{"name":23,"role":19,"phone":24,"phoneExt":10,"email":25},"Terri L Cravener, MS","814-863-9841","eil@psu.edu",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"The Pennsylvania State University","RECRUITING","University Park","Pennsylvania","16802","United States","US",{"type":36,"coordinates":37},"Point",[38,39],-77.85639,40.80201,{"lat":39,"lon":38},[42,43,46],{"name":18,"role":19,"phone":20,"phoneExt":10,"email":21},{"name":44,"role":19,"phone":24,"phoneExt":10,"email":45},"Terri L Cravener, M.S.","eil@psu.esu",{"name":14,"role":15,"phone":10,"phoneExt":10,"email":10},{"type":15,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Kathleen Loralee Keller","Professor",[51,53,55],{"name":52,"class":6},"University of Kansas Medical Center",{"name":54,"class":6},"University of Missouri, Kansas City",{"name":56,"class":57},"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)","NIH","100444880","resilience-to-the-effects-of-advertising-in-children-100444880",false,"NCT05073185","Resilience to the Effects of Advertising in Children","Characterizing Resilience to Food-cue Induced Overeating in Children","REACH","Child Inclusion Criteria:\n\n1. In order to be enrolled, children must be of good health based on parental self-report.\n2. Have no learning disabilities (e.g., ADHD).\n3. Have no allergies to the foods or ingredients used in the study.\n4. Not be claustrophobic.\n5. Not be taking any medications known to influence body weight, taste, food intake, behavior, or blood flow.\n6. Be 7-9 years-old at enrollment.\n7. The child must speak English.\n\nParent Inclusion Criteria:\n\n1. The parent who has the most knowledge of the child's eating behavior, media access, sleep and behavior must be available to attend the visits with their child. This would be decided among the parents.\n2. The biological mother must have a body mass index either between 18.5 - 25 kg\u002Fm2 (low-risk group) or greater than or equal to 30 kg\u002Fm2 (high-risk group). One parent can report on both parents' BW and height.\n\nExclusion Criteria:\n\nChildren would be excluded if:\n\n1. They are not within the age requirements (\\\u003C than 7 years old or \\> than 9 years-old at baseline).\n2. If they are taking cold or allergy medication, or other medications known to influence cognitive function, taste, appetite, or blood flow.\n3. If they don't speak English.\n4. If they are colorblind\n5. If they report being claustrophobic.\n6. if they have a learning disability, ADD\u002FADHD, language delays, autism or other neurological or psychological conditions.\n7. if they have a pre-existing medical condition such as type I or type II diabetes, rheumatoid arthritis, Cushing's syndrome, Down's syndrome, food allergies, severe lactose intolerance, Prader-Willi syndrome, HIV, cancer, renal failure, or cerebral palsy.\n8. if they are allergic to foods or ingredients used in the study.\n9. if they have tattoos, permanent makeup, dental ware, pacemakers, or metal implants that would preclude safe completion of the MRI.\n10. if the child has had an X-ray in the month prior to Visits 1 and 6. If so, they will be scheduled at a later date.\n\nParent Exclusion Criteria:\n\n1. if the biological mother has a body mass index \\\u003C 18.5 kg\u002Fm2\n2. if the mother is between 25-30 kg\u002Fm2.\n3. if the parent is unable to attend the study visits\n4. if the family reports plans to move away from the area in the next year.",true,"ALL","7 Years","9 Years",{"count":71,"type":72},200,"ESTIMATED","OBSERVATIONAL","Strong empirical evidence shows food marketing promotes excess energy intake and obesity. Yet, not all children are susceptible to its effects and this variability is poorly understood. Identifying sources of this variability is a public health priority not only because it may elucidate characteristics of children who are most susceptible, but also because it may highlight novel sources of resiliency to overconsumption. The proposed research will use state-of-the art, data-driven approaches to identify neural, cognitive and behavioral phenotypes associated with resiliency to food-cue (i.e. food advertisement) induced overeating and determine whether these phenotypes protect children from weight gain during the critical pre-adolescent period.",[76],"Obesity, Childhood",[78,79,80,81,82,83],"Obesity","food-cue reactivity","functional magnetic resonance imaging","eating behaviors","food marketing","food advertisement","2026-05-18",{"date":86,"type":87},"2026-05-20","ACTUAL",{"date":89,"type":87},"2022-05-01",{"date":91,"type":72},"2026-12",{"name":5,"class":6},1]