[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100530302":3},{"organization":4,"armGroups":7,"interventions":34,"overallOfficials":51,"centralContacts":60,"locations":67,"responsibleParty":82,"collaborators":85,"id":88,"slug":89,"hasResults":90,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":94,"eligibilityCriteria":95,"healthyVolunteers":96,"sex":97,"minAge":98,"maxAge":38,"enrollmentInfo":99,"targetDuration":38,"studyType":102,"phases":103,"briefSummary":105,"conditions":106,"keywords":38,"overallStatus":69,"whyStopped":38,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":118},{"fullName":5,"class":6},"University of Beira Interior","OTHER",[8,14,19,24,29],{"label":9,"type":10,"description":11,"interventionNames":12},"One Resistance Training Set (Single Session)","EXPERIMENTAL","The participants will perform one resistance training session with one set.",[13],"Other: One Resistance Training Set (Single Session)",{"label":15,"type":10,"description":16,"interventionNames":17},"Three Resistance Training Sets (Single Session)","The participants will perform one resistance training session with three sets.",[18],"Other: Three Resistance Training Sets (Single Session)",{"label":20,"type":10,"description":21,"interventionNames":22},"One Resistance Training Set (8 Weeks)","The participants will perform eight weeks of resistance training (two sessions per week, separated by 72 hours of rest) with one set.",[23],"Other: One Resistance Training Set (8 Weeks)",{"label":25,"type":10,"description":26,"interventionNames":27},"Three Resistance Training Sets (8 Weeks)","The participants will perform eight weeks of resistance training (two sessions per week, separated by 72 hours of rest) with three sets.",[28],"Other: Three Resistance Training Sets (8 Weeks)",{"label":30,"type":10,"description":31,"interventionNames":32},"Control (8 Weeks)","The participants will not perform any form of physical exercise during the intervention period of eight weeks.",[33],"Other: Control (8 Weeks)",[35,39,42,45,48],{"type":6,"name":9,"description":36,"armGroupLabels":37,"otherNames":38},"The participants will perform a resistance training session with one set per exercise. The training sequence will be the following: i) 10 minutes of warm-up walking on the treadmill at 50% of maximal walking velocity, ii) 1 set of 10 repetitions at 60% of one-repetition maximum (1RM) in the leg press, iii) 1 set of 10 repetitions at 55% 1RM in the chest press, iv) 1 set of 10 repetitions in the sit-to-stand exercise, v) 1 set of 10 repetitions in the 1-kg medicine ball throw exercise, and vi) 5 minutes walking on the treadmill at 60% of maximal walking velocity.",[9],null,{"type":6,"name":15,"description":40,"armGroupLabels":41,"otherNames":38},"The participants will perform a resistance training session with three sets per exercise. The training sequence will be the following: i) 10 minutes of warm-up walking on the treadmill at 50% of maximal walking velocity, ii) 3 sets of 10 repetitions at 60% of one-repetition maximum (1RM) in the leg press, iii) 3 sets of 10 repetitions at 55% 1RM in the chest press, iv) 3 sets of 10 repetitions in the sit-to-stand exercise, v) 3 sets of 10 repetitions in the 1-kg medicine ball throw exercise, and vi) 5 minutes walking on the treadmill at 60% of maximal walking velocity.",[15],{"type":6,"name":20,"description":43,"armGroupLabels":44,"otherNames":38},"The participants will perform eight weeks of resistance training with one set per exercise. The training sequence will be the following: i) 10 minutes of warm-up walking on the treadmill at 50% of maximal walking velocity, ii) 1 set of 10 repetitions between 50-70% of one-repetition maximum (1RM) in the leg press, iii) 1 set of 10 repetitions between 40-60% 1RM in the chest press, iv) 1 set of 6-12 repetitions in the sit-to-stand exercise, v) 1 set of 6-12 repetitions in the 1-kg medicine ball throw exercise, and vi) 5 minutes walking on the treadmill at 60% of maximal walking velocity.",[20],{"type":6,"name":25,"description":46,"armGroupLabels":47,"otherNames":38},"The participants will perform eight weeks of resistance training with three sets per exercise. The training sequence will be the following: i) 10 minutes of warm-up walking on the treadmill at 50% of maximal walking velocity, ii) 3 sets of 10 repetitions between 50-70% of one-repetition maximum (1RM) in the leg press, iii) 3 sets of 10 repetitions between 40-60% 1RM in the chest press, iv) 3 sets of 6-12 repetitions in the sit-to-stand exercise, v) 3 sets of 6-12 repetitions in the 1-kg medicine ball throw exercise, and vi) 5 minutes walking on the treadmill at 60% of maximal walking velocity.",[25],{"type":6,"name":30,"description":49,"armGroupLabels":50,"otherNames":38},"The participants in the control group will maintain their regular daily activities without performing any form of physical exercise.",[30],[52,55,57],{"name":53,"affiliation":5,"role":54},"Mário C Marques, PhD","PRINCIPAL_INVESTIGATOR",{"name":56,"affiliation":5,"role":54},"Dulce Esteves, PhD",{"name":58,"affiliation":59,"role":54},"Mikel Izquierdo, PhD","Universidad Pública de Navarra",[61],{"name":62,"role":63,"phone":64,"phoneExt":65,"email":66},"Nuno Fonseca, Master's","CONTACT","918241354","+351","nuno1977fonseca@gmail.com",[68],{"facility":5,"status":69,"city":70,"state":38,"zip":38,"country":71,"countryCode":72,"cosmosGeoPoint":73,"geoPoint":78,"contacts":79},"RECRUITING","Covilha","Portugal","PT",{"type":74,"coordinates":75},"Point",[76,77],-7.50504,40.28106,{"lat":77,"lon":76},[80],{"name":81,"role":63,"phone":38,"phoneExt":38,"email":38},"Nuno Fonseca",{"type":54,"investigatorFullName":83,"investigatorTitle":84,"investigatorAffiliation":5,"oldNameTitle":38,"oldOrganization":38},"Nuno Miguel Pintassilgo da Silva Fonseca","Researcher",[86],{"name":87,"class":6},"Research Center in Sports Sciences, Health Sciences and Human Development","100530302","resistance-training-to-individuals-for-cognitive-impairment-with-dementia-100530302",false,"NCT06185010","Resistance Training to Individuals for Cognitive Impairment With Dementia","Effects of Different Resistance Training Volumes on Cognitive Function, Oxidative Stress, Immunological Response, Lipid Profile, Glycemic Status, Liver Function, Muscle Function, Hemodynamic Response, and Physical Performance in Individuals With Mild Cognitive Impairment","TRAIN4BRAIN","Inclusion criteria:\n\n* Clinical diagnosis of mild cognitive impairment\n* SPPB score ≥ 3 points\n* Willingness to participate in the interventions and collaborate with the research team\n* Must be able to provide informed consent (oral or written)\n\nExclusion criteria:\n\n* Severe dementia\n* Severe comorbidity that negatively influences participation in the intervention\n* Color blindness\n* Fractures in the last three months",true,"ALL","50 Years",{"count":100,"type":101},80,"ESTIMATED","INTERVENTIONAL",[104],"NA","This research project aims to analyze the effects of different resistance training volumes on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment. First the investigators will analyze the effects of a single resistance training session (acute effects) with one and three sets on hemodynamic and physical performance in individuals with mild cognitive impairment. After, the investigators will analyze the effects of an 8-week resistance training program with one or three sets on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment. The investigators hypothesize that a single resistance training session of one or three sets will increase the acute hemodynamic and physical performance stress in individuals with mild cognitive impairment, although with a higher magnitude in the session with three sets. Furthermore, we hypothesize that eight weeks of resistance training with one or three sets will induce similar improvements in cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment.",[107,108],"Mild Cognitive Impairment","Mild Dementia","2024-08-01",{"date":111,"type":112},"2024-08-06","ACTUAL",{"date":114,"type":112},"2023-12-01",{"date":116,"type":101},"2024-12-31",{"name":5,"class":6},1]