[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579996":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":31,"locations":36,"responsibleParty":132,"collaborators":18,"id":134,"slug":135,"hasResults":136,"nctId":137,"briefTitle":138,"officialTitle":139,"acronym":140,"eligibilityCriteria":141,"healthyVolunteers":136,"sex":142,"minAge":18,"maxAge":143,"enrollmentInfo":144,"targetDuration":18,"studyType":147,"phases":148,"briefSummary":150,"conditions":151,"keywords":154,"overallStatus":39,"whyStopped":18,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":163,"locationsCount":164},{"fullName":5,"class":6},"Dana-Farber Cancer Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm 1: RISE Intervention + Usual Supportive Care","EXPERIMENTAL","Participants will be randomized in a 1:1 ratio and stratified according to treatment group and Household Material Hardship (HMH) severity score. Participant parents\u002Fguardians will complete:\n\n* Orientation visit in-person, by phone, or virtually with survey\n* Access to usual supportive oncology care comprised of social workers, resource specialists and\u002For psychosocial oncology teams\n* Meeting with a benefits counselor by phone or virtually and follow up meetings if needed\n* Fixed amount of cash assistance 2x monthly\n* 3 months survey\n* 6 month survey",[13],"Behavioral: RISE Intervention",{"label":15,"type":16,"description":17,"interventionNames":18},"Arm 2: Usual Supportive Care","NO_INTERVENTION","Participants will be randomized in a 1:1 ratio and stratified according to treatment group and HMH severity score. Participant parents\u002Fguardians will complete:\n\n* Orientation visit in-person, by phone, or virtually with survey\n* Access to usual supportive oncology care comprised of social workers, resource specialists and\u002For psychosocial oncology teams\n* 3 month survey\n* 6 month survey",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","RISE Intervention","Income-poverty targeted, supportive care intervention that includes direct cash transfers delivered by the Fund for Guaranteed Income, a non-profit organization, along with benefits counseling to discuss the risk of means-tested benefits loss or reduction. Funds will be dispersed to families via debit card or through personal banking, PayPal, or Venmo on a twice monthly basis for a total of twelve disbursements (6-months). Meetings with a benefits counselor will be conducted by the HIPAA-compliant video conference platform, Zoom.",[9],[26],"Pediatric Resource Intervention to Support Equity",[28],{"name":29,"affiliation":5,"role":30},"Kira Bona, MD, MPH","PRINCIPAL_INVESTIGATOR",[32],{"name":29,"role":33,"phone":34,"phoneExt":18,"email":35},"CONTACT","617-632-4688","Kira_Bona@dfci.harvard.edu",[37,56,71,84,99,114],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Connecticut Children's Medical Center","RECRUITING","Hartford","Connecticut","06106","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-72.68509,41.76371,{"lat":49,"lon":48},[52],{"name":53,"role":33,"phone":54,"phoneExt":18,"email":55},"Andrea Orsey, MD, MSCE","860-545-9630","aorsey@connecticutchildrens.org",{"facility":57,"status":39,"city":58,"state":59,"zip":60,"country":43,"countryCode":44,"cosmosGeoPoint":61,"geoPoint":65,"contacts":66},"Children's Healthcare of Atlanta","Atlanta","Georgia","30329",{"type":46,"coordinates":62},[63,64],-84.38798,33.749,{"lat":64,"lon":63},[67],{"name":68,"role":33,"phone":69,"phoneExt":18,"email":70},"Thomas Cash, MD","404-785-1200","william.cash@choa.org",{"facility":5,"status":39,"city":72,"state":73,"zip":74,"country":43,"countryCode":44,"cosmosGeoPoint":75,"geoPoint":79,"contacts":80},"Boston","Massachusetts","03079",{"type":46,"coordinates":76},[77,78],-71.05977,42.35843,{"lat":78,"lon":77},[81],{"name":29,"role":33,"phone":82,"phoneExt":18,"email":83},"203-464-9417","kira.bona@childrens.harvard.edu",{"facility":85,"status":39,"city":86,"state":87,"zip":88,"country":43,"countryCode":44,"cosmosGeoPoint":89,"geoPoint":93,"contacts":94},"Children's Hospital of Philadelphia","Philadelphia","Pennsylvania","19104",{"type":46,"coordinates":90},[91,92],-75.16362,39.95238,{"lat":92,"lon":91},[95],{"name":96,"role":33,"phone":97,"phoneExt":18,"email":98},"Rochelle Bagatell, MD","267-426-9737","bagatellr@chop.edu",{"facility":100,"status":39,"city":101,"state":102,"zip":103,"country":43,"countryCode":44,"cosmosGeoPoint":104,"geoPoint":108,"contacts":109},"University of Texas Southwestern Medical Center","Dallas","Texas","75390",{"type":46,"coordinates":105},[106,107],-96.80667,32.78306,{"lat":107,"lon":106},[110],{"name":111,"role":33,"phone":112,"phoneExt":18,"email":113},"Puja Umaretiya, MD","(214) 456-2382","puja.umaretiya@utsouthwestern.edu",{"facility":115,"status":39,"city":116,"state":117,"zip":118,"country":43,"countryCode":44,"cosmosGeoPoint":119,"geoPoint":123,"contacts":124},"Seattle Children's Hospital","Seattle","Washington","98105",{"type":46,"coordinates":120},[121,122],-122.33207,47.60621,{"lat":122,"lon":121},[125,129],{"name":126,"role":33,"phone":127,"phoneExt":18,"email":128},"Anurekha Hall, MD","206-987-2106","anurekha.hall@seattlechildrens.org",{"name":130,"role":33,"phone":18,"phoneExt":18,"email":131},"Kristine Karvonen, MD","Kristine.Karvonen@seattlechildrens.org",{"type":30,"investigatorFullName":29,"investigatorTitle":133,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Principal Investigator","100579996","resource-intervention-to-support-equity-rise-in-high-risk-neuroblastoma-100579996",false,"NCT06831552","Resource Intervention to Support Equity (RISE) in High-Risk Neuroblastoma","A Randomized Phase II Trial Evaluation of the Addition of the Resource Intervention to Support Equity (RISE) to Usual Supportive Care for Children With Newly Diagnosed High-Risk Neuroblastoma","RISE in HR NBL","Inclusion Criteria:\n\nPatient cohort: The randomized Phase II multi-center RISE intervention will be conducted among a population of poverty-exposed children with high-risk neuroblastoma. Poverty will be a priori defined as parent-reported low-income (\\\u003C200% Federal Poverty Level). Children receiving treatment for cancer at study sites will serve as the study cohort, with parents\u002Fguardians as survey informants and intervention recipients on behalf of their minor children given that parents (not children) typically manage household finances.\n\n* Patient newly diagnosed with high-risk neuroblastoma\n* Patient has established care at study site and initiated cancer-directed therapy\n* Patient has not yet initiated Induction Cycle 3\n* Patient aged 0-17 years at the time of consent\n* Parent\u002Fguardian screened positive for self-reported low-income (\\\u003C200% Federal Poverty) \\*\n* Family primary residence in MA, PA, IL, CA, WA, CT, GA, WI and OH\n* Both patients co-enrolled on ANBL2131 or those receiving standard of care therapy at their center are eligible to participate\n* Patients of all languages are eligible to participate\n\nExclusion Criteria:\n\n* Foreign national family receiving care as an Embassy-pay patient.\n* Child or household member receiving SSI","ALL","17 Years",{"count":145,"type":146},84,"ESTIMATED","INTERVENTIONAL",[149],"NA","The goal of this study is to test if the addition of a novel income-poverty targeted supportive care intervention (Pediatric Resource Intervention to Support Equity \\[Pediatric RISE\\]) to usual supportive care for low-income children with high-risk neuroblastoma can improve parent- and child-centered outcomes.\n\nParticipants will be randomized to receive one of the following for 6-months:\n\n* Usual supportive care alone or\n* Usual supportive care plus Pediatric RISE",[152,153],"Neuroblastoma","High-risk Neuroblastoma",[152,153],"2026-02-09",{"date":157,"type":158},"2026-02-10","ACTUAL",{"date":160,"type":158},"2025-04-30",{"date":162,"type":146},"2029-06-01",{"name":5,"class":6},6]