[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621388":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":37,"locations":25,"responsibleParty":44,"collaborators":25,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":25,"maxAge":25,"enrollmentInfo":55,"targetDuration":25,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":25,"overallStatus":64,"whyStopped":25,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":25},{"fullName":5,"class":6},"Universidad de Granada","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment Arm","EXPERIMENTAL","Participants will receive diaphragmatic biofeedback combined with respiratory muscle training three times per day for 6 weeks",[13],"Other: Diaphragmatic biofeedback combined with respiratory muscle training",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Arm","PLACEBO_COMPARATOR","Placebo intervention based on conscious breathing three times per day for 6 weeks",[19],"Other: PLACEBO INTERVENTION",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Diaphragmatic biofeedback combined with respiratory muscle training","This intervention is novel because it integrates diaphragmatic biofeedback into a structured respiratory muscle training program specifically designed for patients with chronic kidney disease, a population in which respiratory dysfunction is prevalent yet under-addressed. By providing real-time feedback on diaphragmatic activity, the intervention aims to enhance motor learning, improve activation of the diaphragm, and optimize training efficiency beyond conventional breathing or respiratory muscle training approaches.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"PLACEBO INTERVENTION","The placebo intervention will consist of concious guided breathing sessions based on the participant's subjective respiratory sensations, without the use of objective physiological feedback or diaphragm-specific biofeedback. Participants will be instructed to follow standardized breathing guidance focused on perceived comfort and awareness, matching the intervention group in session frequency and duration.",[15],[31,34],{"name":32,"affiliation":5,"role":33},"Alejandro Heredia-Ciuró, PhD","PRINCIPAL_INVESTIGATOR",{"name":35,"affiliation":5,"role":36},"Marie Carmen Valenza, PhD","STUDY_DIRECTOR",[38],{"name":39,"role":40,"phone":41,"phoneExt":42,"email":43},"Marie Carmen Valenza, PhD University Professor","CONTACT","958248035","+34","cvalenza@ugr.es",{"type":33,"investigatorFullName":45,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Marie Carmen Valenza","Principal Investigator","100621388","respiratory-biofeedback-added-to-strengthening-training-in-patients-with-chronic-kidney-disease-100621388",false,"NCT07369973","Respiratory Biofeedback Added to Strengthening Training in Patients With Chronic Kidney Disease","RESPI-REN","Inclusion Criteria:\n\n* Adults aged ≥18 years\n* Diagnosis of chronic kidney disease (CKD) at any stage\n* Clinically stable condition, with no acute medical events in the previous 4 weeks\n* Ability to understand and follow breathing and training instructions\n* Willingness to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Acute respiratory infection or unstable pulmonary disease\n* Severe cognitive impairment or neurological condition limiting cooperation\n* Unstable cardiovascular disease or contraindications to respiratory muscle training\n* Recent thoracic or abdominal surgery (\\\u003C3 months)\n* Significant visual impairment that prevents proper use of the biofeedback device\n* Participation in another interventional clinical trial during the study period","ALL",{"count":56,"type":57},24,"ESTIMATED","INTERVENTIONAL",[60],"NA","The goal of this clinical trial is to learn whether diaphragmatic biofeedback added to respiratory muscle training improves clinical and functional outcomes in adults with chronic kidney disease. It will also evaluate the feasibility and acceptability of this intervention.\n\nThe main questions it aims to answer are:\n\nIs diaphragmatic biofeedback added to respiratory muscle training acceptable and well tolerated in patients with chronic kidney disease? Does this intervention reduce respiratory symptoms and complications in this population? Does diaphragmatic biofeedback added to respiratory muscle training improve cardiorespiratory capacity and quality of life? Researchers will evaluate diaphragmatic biofeedback combined with respiratory muscle training and a placebo intervention based on conscious breathing to assess its effects.\n\nParticipants will:\n\n* Perform the assigned intervention three times per day for 6 weeks\n* Follow a structured respiratory muscle training program with diaphragmatic biofeedback\n* Be monitored for symptoms, respiratory complications, and perceived quality of life throughout the study",[63],"Chronic Kidney Disease (Stages 4 and 5)","NOT_YET_RECRUITING","2026-01-18",{"date":67,"type":68},"2026-01-27","ACTUAL",{"date":70,"type":57},"2026-01",{"date":72,"type":57},"2026-08",{"name":5,"class":6}]