[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100532781":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":11,"centralContacts":22,"locations":28,"responsibleParty":46,"collaborators":11,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":11,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":11,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":11,"overallStatus":31,"whyStopped":11,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Istanbul Medipol University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"COPD Group","ACTIVE_COMPARATOR",null,[13],"Other: Respiratory muscle fatigue protocol",{"label":15,"type":10,"description":11,"interventionNames":16},"Healthy Group",[13],[18],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":11},"Respiratory muscle fatigue protocol","It will be performed using a powerbreath device at 60% of the maximum inspiratory pressure (MIP) amount obtained by measuring mouth pressure. The protocol includes 7 sets consisting of 2 minutes of inspiratory effort and 1 minute of rest. To further confirm the occurrence of fatigue, the patient will score fatigue using the modified Borg scale, and the score will be 5 or above11. During the application, heart rate, blood pressure and peripheral oxygen saturation will be monitored. The measurement will be performed once for each case.",[9,15],[23],{"name":24,"role":25,"phone":26,"phoneExt":11,"email":27},"ESRA PEHLİVAN","CONTACT","09050585279","fztesrakambur@yahoo.com",[29],{"facility":30,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":11,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Yedikule Chest Disease Hospital","RECRUITING","Istanbul","Zeytinburnu","34200","Turkey (Türkiye)",{"type":37,"coordinates":38},"Point",[39,40],28.94966,41.01384,{"lat":40,"lon":39},[43],{"name":44,"role":25,"phone":45,"phoneExt":11,"email":27},"Esra Pehlivan","+902124090200",{"type":47,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":50,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","esra pehlivan","Principal Investigator","Saglik Bilimleri Universitesi","100532781","respiratory-muscle-fatigue-and-lower-extremity-muscle-oxygenation-100532781",false,"NCT06217276","Respiratory Muscle Fatigue and Lower Extremity Muscle Oxygenation","Examining the Relationship Between Respiratory Muscle Fatigue and Lower Extremity Muscle Oxygenation in Chronic Obstructive Pulmonary Disease Patients.","Inclusion Criteria:\n\n* Having a diagnosis of Stage 2-3 COPD according to the following clinical diagnostic criteria according to the American Thoracic and European Respiratory Societies (ATS-ERS).\n* Having been using the same medications for the last 4 weeks\n\nExclusion Criteria:\n\n* Patients with severe comorbid diseases, unstable coronary artery disease, collagen vascular diseases and requiring high-flow oxygen therapy (˃ 3-4 L\\\\min).\n* Presence of any vascular problem that may affect lower extremity muscle oxygenation\n* Presence of another respiratory system disease other than COPD\n* Patients who have had an acute COPD exacerbation in the last 4 weeks\n* Patients experiencing COPD exacerbations during the study protocol\n* Presence of fatty tissue or scar tissue at the measurement points, which may impair the measurement quality.\n* Have already participated in another clinical trial within the last 30 days that may affect the results of the study.\n\nInclusion Criteria for Healthy Cases\n\n* Being over 18 years of age\n* Not having any diagnosed chronic disease\n* Not being a smoker",true,"ALL","18 Years","75 Years",{"count":63,"type":64},30,"ESTIMATED","INTERVENTIONAL",[67],"NA","In our study, changes in vastus lateralis muscle oxygenation will be evaluated with the Moxy device, a functional infrared oxygen measurement device, during the inspiratory muscle fatigue protocol in COPD cases and the healthy control group.",[70],"COPD","2025-04-29",{"date":73,"type":74},"2025-05-01","ACTUAL",{"date":76,"type":74},"2024-01-20",{"date":78,"type":64},"2026-01-15",{"name":5,"class":6},1]