[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100502079":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":29,"responsibleParty":157,"collaborators":10,"id":159,"slug":160,"hasResults":161,"nctId":162,"briefTitle":163,"officialTitle":163,"acronym":164,"eligibilityCriteria":165,"healthyVolunteers":161,"sex":166,"minAge":167,"maxAge":10,"enrollmentInfo":168,"targetDuration":10,"studyType":171,"phases":10,"briefSummary":172,"conditions":173,"keywords":10,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":175,"lastUpdatePostDateStruct":176,"startDateStruct":179,"completionDateStruct":181,"leadSponsor":183,"locationsCount":184},{"fullName":5,"class":6},"Centre Hospitalier Annecy Genevois","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with peripheral neuropathic pain and having an indication of capsaicin patches",null,"All patients will receive as part of routine care:\n\n* Three consecutive patches of 8% capsaicin in localized application for 30 to 60 minutes once every 3 months : at M0 (study inclusion), M3 and M6, or until pain scale \\\u003C 4\u002F10 (between 0 and 10),\n* Pain assessment every 1.5 months (+\u002F-7 days), to evaluate clinical response,\n* 8% capsaicin patches if the pain assessment rises again to pain scale \\> 4\u002F10, after an initial response to treatment",[13],"Other: Questionnaires",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Questionnaires","In current practice, capsaicin patch treatment is offered to patients with a 24-hour average pain level measured by the EN numerical scale : EN scale is \\> 4 Pain monitoring questionnaires will be completed by patients every 6 weeks : Neuropathic Pain Symptom Invetory (NPSI Score), Patients' Global Impression of Change (PGIC scale), Numerical pain scale",[9],[20],{"name":21,"affiliation":5,"role":22},"Stéphane FERRANDO, Doctor","PRINCIPAL_INVESTIGATOR",[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Marion GHIDI","CONTACT","+33450637031","drci.promotion@ch-annecygenevois.fr",[30,45,59,72,85,98,111,121,134,144],{"facility":5,"status":31,"city":32,"state":10,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"RECRUITING","Annecy","74370","France","FR",{"type":37,"coordinates":38},"Point",[39,40],6.12565,45.90878,{"lat":40,"lon":39},[43],{"name":21,"role":26,"phone":10,"phoneExt":10,"email":44},"sferrando@ch-annecygenevois.fr",{"facility":46,"status":47,"city":48,"state":10,"zip":49,"country":34,"countryCode":35,"cosmosGeoPoint":50,"geoPoint":54,"contacts":55},"Hospices Civils de Lyon, Hôpital Pierre Wertheimer","NOT_YET_RECRUITING","Bron","69500",{"type":37,"coordinates":51},[52,53],4.91303,45.73865,{"lat":53,"lon":52},[56],{"name":57,"role":26,"phone":10,"phoneExt":10,"email":58},"Christian GOV, Doctor","Christian.gov@chu-lyon.fr",{"facility":60,"status":31,"city":61,"state":10,"zip":62,"country":34,"countryCode":35,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"Centre Hospitalier Métropole Savoie","Chambéry","73000",{"type":37,"coordinates":64},[65,66],5.92079,45.56628,{"lat":66,"lon":65},[69],{"name":70,"role":26,"phone":10,"phoneExt":10,"email":71},"Valérie ROULLOT-PRADEL, Doctor","valerie.roullot.pradel@ch-metropole-savoie.fr",{"facility":73,"status":47,"city":74,"state":10,"zip":75,"country":34,"countryCode":35,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"Centre Hospitalier Universitaire de Clermont-Ferrand","Clermont-Ferrand","63000",{"type":37,"coordinates":77},[78,79],3.08682,45.77969,{"lat":79,"lon":78},[82],{"name":83,"role":26,"phone":10,"phoneExt":10,"email":84},"Noémie DELAGE, Doctor","ndelage@chu-clermontferrand.fr",{"facility":86,"status":31,"city":87,"state":10,"zip":88,"country":34,"countryCode":35,"cosmosGeoPoint":89,"geoPoint":93,"contacts":94},"Centre Hospitalier Universitaire Grenoble-Alpes","Grenoble","38043",{"type":37,"coordinates":90},[91,92],5.71479,45.17869,{"lat":92,"lon":91},[95],{"name":96,"role":26,"phone":10,"phoneExt":10,"email":97},"Caroline MAINDET, Doctor","cmaindet@chu-grenoble.fr",{"facility":99,"status":47,"city":100,"state":10,"zip":101,"country":34,"countryCode":35,"cosmosGeoPoint":102,"geoPoint":106,"contacts":107},"Hospices Civils de Lyon, Hôpital de la Croix Rousse","Lyon","69317",{"type":37,"coordinates":103},[104,105],4.84789,45.74906,{"lat":105,"lon":104},[108],{"name":109,"role":26,"phone":10,"phoneExt":10,"email":110},"Mikhail DZIADZKO, Doctor","mikhail.dziadzko@chu-lyon.fr",{"facility":112,"status":31,"city":100,"state":10,"zip":113,"country":34,"countryCode":35,"cosmosGeoPoint":114,"geoPoint":116,"contacts":117},"Centre Léon Bérard","69373",{"type":37,"coordinates":115},[104,105],{"lat":105,"lon":104},[118],{"name":119,"role":26,"phone":10,"phoneExt":10,"email":120},"Olivier RENARD, Doctor","olivier.renard@lyon.unicancer.fr",{"facility":122,"status":47,"city":123,"state":10,"zip":124,"country":34,"countryCode":35,"cosmosGeoPoint":125,"geoPoint":129,"contacts":130},"Centre Hospitalier Universitaire de Saint-Etienne","Saint-Etienne","42055",{"type":37,"coordinates":126},[127,128],4.39,45.43389,{"lat":128,"lon":127},[131],{"name":132,"role":26,"phone":10,"phoneExt":10,"email":133},"Christelle CREAC'H, Doctor","christelle.creach@univ-st-etienne.fr",{"facility":135,"status":31,"city":123,"state":10,"zip":136,"country":34,"countryCode":35,"cosmosGeoPoint":137,"geoPoint":139,"contacts":140},"Clinique Mutualiste Chirurgicale de Saint Etienne","42100",{"type":37,"coordinates":138},[127,128],{"lat":128,"lon":127},[141],{"name":142,"role":26,"phone":10,"phoneExt":10,"email":143},"Denis BAYLOT, Doctor","Denis.BAYLOT@lyon.unicancer.fr",{"facility":145,"status":47,"city":146,"state":10,"zip":147,"country":34,"countryCode":35,"cosmosGeoPoint":148,"geoPoint":152,"contacts":153},"Médipôle Lyon Villeurbanne","Villeurbanne","69100",{"type":37,"coordinates":149},[150,151],4.8795,45.76601,{"lat":151,"lon":150},[154],{"name":155,"role":26,"phone":10,"phoneExt":10,"email":156},"Mario BARMAKI, Doctor","mariobarmaki@aol.com",{"type":158,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100502079","response-profiles-to-high-concentration-capsaicin-desensitization-in-patients-with-peripheral-neuropathic-pain-with-or-without-allodynia-a-regional-multicenter-prospective-cohort-100502079",false,"NCT05817591","Response Profiles to High-concentration Capsaicin Desensitization in Patients with Peripheral Neuropathic Pain with or Without Allodynia: a Regional Multicenter Prospective Cohort","CAPSICAURA","Inclusion Criteria:\n\n* Patient over 18 years of age on the day of inclusion\n* Patient who has been informed and has not expressed opposition to participating in the study,\n* Patient with peripheral neuropathic pain (whatever the etiology), defined by :\n\n  * \"Neuropathic Pain 4\" score (\"DN4\" score) ≥ 4\u002F10\n  * AND pain according to the numerical scale (EN) \\> 4\u002F10,\n  * AND stable analgesic treatment for at least 1 month,\n  * AND with or without mechanical allodynia according to the Quantitative Sensory Testing (QST) : Brush test (dynamic), Von Frey test (static)\n  * AND with or without thermal allodynia to hot or cold as determined by a ROLLTEMP-II® (Rolltemp is a device designed for quick screening of temperature sensibility over large body areas).\n* Patient responding to an indication of desensitization to high concentration capsaicin concentration and not presenting any contra-indication.\n* Patient naïve of high concentration of Capsaicin on the concerned zone\n* Patient understanding French\n\nNon-inclusion Criteria:\n\n* Patient with pain related to complex regional pain syndrome (criteria not meeting the indication for capsaicin)\n* Patient with active cancer (underlying disease and treatments may modify pain perception),\n* Patient receiving or having received in the last 3 months Botulinum toxin A on the concerned area (this treatment of neuropathic pain may modulate the effect of capsaicin and disturb the demonstration of causality),\n* Patient with planned surgery within the next 12 months on the painful site (surgery may cause neuropathic damage and\u002For bias the pain assessment),\n* Patient included in an interventional research protocol,\n* Patient under guardianship or curators,\n* Patient under legal protection\n\nExclusion Criteria:\n\nNone","ALL","18 Years",{"count":169,"type":170},400,"ESTIMATED","OBSERVATIONAL","Prospective multicenter cohort to determine patient profiles (associated factors, including allodynia) with a better response to pain desensitization by capsaicin delivered in the form of a high concentration patch (8%), in a population of patients with peripheral neuropathic pain and followed up in a pain consultation in the Auvergne Rhône Alpes region.",[174],"Peripheral Neuropathic Pain","2025-02-11",{"date":177,"type":178},"2025-02-13","ACTUAL",{"date":180,"type":178},"2023-12-14",{"date":182,"type":170},"2026-06-15",{"name":5,"class":6},10]