[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100550831":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":37,"locations":47,"responsibleParty":68,"collaborators":71,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":26,"eligibilityCriteria":80,"healthyVolunteers":76,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":26,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":49,"whyStopped":26,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"North Carolina State University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"dEMG group","EXPERIMENTAL","Patients go through the training procedure with the direct EMG controlled powered prosthetic ankle.",[13,14],"Device: direct EMG controlled prosthetic ankle","Behavioral: PT guided prosthetic training",{"label":16,"type":17,"description":18,"interventionNames":19},"Passive group","ACTIVE_COMPARATOR","Patients go through the training procedure with their own passive prosthetic ankles",[14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","direct EMG controlled prosthetic ankle","Patients are trained to use the powered prosthetic ankles",[9],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":26},"BEHAVIORAL","PT guided prosthetic training","Amputees are trained to use prosthetic ankles",[16,9],[33],{"name":34,"affiliation":35,"role":36},"He Huang, PhD","NC State University","PRINCIPAL_INVESTIGATOR",[38,43],{"name":39,"role":40,"phone":41,"phoneExt":26,"email":42},"Neuromuscular Rehabilitation Engineering Laboratory","CONTACT","919-513-3840","nrel.ncsu.contact@gmail.com",{"name":44,"role":40,"phone":45,"phoneExt":26,"email":46},"Ming Liu, PhD","919-515-8543","mliu10@ncsu.edu",[48],{"facility":5,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"RECRUITING","Raleigh","North Carolina","27695","United States","US",{"type":56,"coordinates":57},"Point",[58,59],-78.63861,35.7721,{"lat":59,"lon":58},[62,65],{"name":34,"role":40,"phone":63,"phoneExt":26,"email":64},"919-515-5218","hhuang11@ncsu.edu",{"name":66,"role":40,"phone":41,"phoneExt":26,"email":67},"Laura Rohrbaugh","lasmith6@ncsu.edu",{"type":36,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"He Huang","Professor",[72],{"name":73,"class":6},"University of North Carolina, Chapel Hill","100550831","restoration-of-normative-postural-control-100550831",false,"NCT06452186","Restoration of Normative Postural Control","Toward Restoration of Normative Postural Control and Stability Using Neural Control of Powered Prosthetic Ankles","Inclusion Criteria:\n\n* 18 years or older;\n* unilateral bower limb amputee\n* K-level 2 or higher (who are frequent prosthesis users and may benefit from the proposed prosthesis training and use of dEMG controlled powered prosthesis)\n* Amputation occurred over 2 years ago\n* At least 1 year of experience using their prosthetic leg\n* Has used the current socket for at least 6 months without a significant skin issue or major modification\n* Are willing to come to NC State University's Centennial Campus to participate in research and be photographed while doing research activities\n\nExclusion Criteria:\n\n* Have a very short residual shank (the length of the residual limb is ≤15% of the length of intact limb)\n* Cannot perform functional ambulation in the community on a daily basis without assistive devices\n* Cognitive or visual impairment that affects the participant's ability to provide informed consent or to follow simple instructions during the experiments\n* Congenital amputees\n* Amputees who use powered prosthetic ankles\n* Weight more than 300lbs\n* Pregnant Person\n* Allergic to latex, which is often contained in medical tapes.","ALL","18 Years","99 Years",{"count":85,"type":86},50,"ESTIMATED","INTERVENTIONAL",[89],"NA","The objective of this proposal is to investigate the effects of training to use direct electromyographic (dEMG) control of a powered prosthetic ankle on transtibial amputees'.\n\nThe aimed questions to answer:\n\n1. whether dEMG control will improve balance and postural stability of amputees,\n2. whether dEMG control will lead to more natural neuromuscular control and coordination, 3) whether dEMG control will reduce cognitive processes.\n\nParticipants will go through PT guided training on using dEMG controlled prosthetic ankles and are evaluated for their capability on functional tasks.\n\nThe results will be compared with a comparison group, which goes through the same training but with their everyday passive prostheses on balance capability, neuromuscular coordination, and cognitive load during locomotion.",[92],"Lower Limb Amputation Below Knee (Injury)",[94,95,96,97,98],"powered ankle prosthesis","direct EMG control","balance","cognitive load","muscle synergy","2026-06-30",{"date":101,"type":102},"2026-07-02","ACTUAL",{"date":104,"type":102},"2023-10-01",{"date":106,"type":86},"2028-06-30",{"name":5,"class":6},1]