[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100542014":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":39,"responsibleParty":56,"collaborators":18,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":18,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":18,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":80,"overallStatus":41,"whyStopped":18,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"National Geriatric Hospital","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention group","EXPERIMENTAL","The intervention group receives supervised resistance training instructions and baseline treatment for sarcopenia and diabetes:\n\n* Resistance training with elastic bands aims to increase muscle strength and muscle mass of the upper and lower limbs. Training duration 12 weeks, frequency 2 times\u002Fweek, intensity gradually increases.\n* Baseline treatment for diabetes and sarcopenia: Recommendations according to American Diabetes Association guidelines which include instructions to follow the diet and exercises as recommended for older type 2 diabetic patients and baseline treatment for sarcopenia (education about sarcopenia and treatment measures such as diet and exercise) and provide basic information on resistance training.",[13],"Behavioral: Progressive Resistance Training",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","NO_INTERVENTION","The control group receives the baseline treatment for diabetes and sarcopenia:\n\n\\- Recommendations according to American Diabetes Association guidelines which include instructions to follow the diet and exercises as recommended for older type 2 diabetic patients and baseline treatment for sarcopenia (education about sarcopenia and treatment measures such as diet and exercise) and provide basic information on resistance training.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","Progressive Resistance Training","Progressive resistance training includes face-to-face education on resistance training:\n\nResistance exercises with elastic bands include 9 exercises for 1 course. During the first 4 weeks, the patient exercises twice a week with a level of exertion according to Borg's category-ratio 10 (CR10) scale of 4-5 points. For the next 4 weeks, the patient exercises twice a week with Borg's CR10 exertion level of 6-7 points. In the last 4 weeks, the patient exercises twice a week with Borg's CR10 exertion level of 8-9 points.\n\nThe three-month intervention involves twelve weekly calls, with a focus on building rapport (e.g. providing feedback on the baseline assessment); education reinforcement on resistance training; and skill-building (e.g. self-monitoring and resistance training diary). The emphasis is on helping participants to gain the knowledge and skills necessary to achieve targeted intensity. Every 4 weeks, all patients are re-visited by investigators in the hospital.",[9],[26],{"name":27,"affiliation":5,"role":28},"Huyen TT Vu, PhD","STUDY_CHAIR",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":18,"email":34},"Anh N Trinh, MD","CONTACT","(+84) 912760684","drtrinhanh.endo@gmail.com",{"name":36,"role":32,"phone":37,"phoneExt":18,"email":38},"Tam N Nguyen, PhD","+84979221905","ngoctam@hmu.edu.vn",[40],{"facility":5,"status":41,"city":42,"state":18,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Hanoi","100000","Vietnam","VN",{"type":47,"coordinates":48},"Point",[49,50],105.84117,21.0245,{"lat":50,"lon":49},[53],{"name":27,"role":32,"phone":54,"phoneExt":18,"email":55},"+84913531579","vuthanhhuyen11@yahoo.com",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Trinh Ngoc Anh","Endocrinologist, Principal Investigator and Sponsor","100542014","results-of-progressive-resistance-training-in-older-type-2-diabetic-patients-with-sarcopenia-100542014",false,"NCT06337357","Results of Progressive Resistance Training in Older Type 2 Diabetic Patients With Sarcopenia","Evaluating Resistance Training for Sarcopenia in Older Patients With Type 2 Diabetes: Treatment Outcomes","Inclusion Criteria:\n\n* Type 2 diabetic patients diagnosed using American Diabetes Association 2022 criteria\n* HbA1c ≥ 7.0 and ≤ 8.5%\n* Sarcopenia diagnosed using criteria from the Asian Working Group for Sarcopenia 2019\n* Age ≥ 60 and ≤ 80\n\nExclusion Criteria:\n\n* Acute diabetic complications\n* Patients are in the acute phase of musculoskeletal disorders: acute gout, progressing low-grade arthritis, acute joint pain due to joint degeneration, sciatic pain, and infectious arthritis.\n* Patients suffer from conditions significantly affecting cognition and mobility: sequelae of stroke (with weakness, limb paralysis), muscular weakness, limb disabilities, severe heart failure, severe cognitive decline, and psychiatric disorders.\n* Patients have been bedridden due to illness for more than 1 month within the past 3 months up to the recruitment time.\n* Patients with cardiovascular diseases: chest pain, uncontrolled blood pressure ≥160\u002F100 mmHg, untreated cardiac arrhythmia, a history of congestive heart failure, severe valvular heart disease, myocarditis or pericarditis, and hypertrophic cardiomyopathy.\n* Renal failure with estimated glomerular function rate (Modification of Diet in Renal Disease equation) \\\u003C 60 ml\u002Fmin\u002Fm3 or serum creatinine ≥ 130 µmol\u002Fl\n* On treatment with Sodium-glucose cotransporter 2 inhibitors (SGLT2i)","ALL","60 Years","80 Years",{"count":71,"type":72},80,"ESTIMATED","INTERVENTIONAL",[75],"NA","A randomized controlled clinical trial that will test how progressive resistance training will impact outcomes of sarcopenia in older patients with type 2 diabetes who have been diagnosed as sarcopenia. The intervention will be 12 weeks in duration with approximately 24 sessions of resistance exercises. Outcome measures will be collected at baseline, 4, 8 weeks and 12 weeks.",[78,79],"Sarcopenia","Diabetes",[78,79,81],"Resistance training","2025-05-19",{"date":84,"type":85},"2025-05-22","ACTUAL",{"date":87,"type":85},"2024-04-01",{"date":89,"type":72},"2025-12",{"name":5,"class":6},1]