[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618320":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":28,"responsibleParty":52,"collaborators":10,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":10,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":69,"studyType":70,"phases":10,"briefSummary":71,"conditions":72,"keywords":76,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Foundation University Islamabad","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Group 1: pit and fissure sealant non carious enamel lesions (ICDAS score 0)",null,"pits and fissure sealants will be applied in non carious (sound) enamel surfaces of posterior permanent teeth and the retention will the evaluated at 3, 6 , and 12 months.",{"label":13,"type":10,"description":14,"interventionNames":10},"Group 2: pit and fissure sealant on Initial caries enamel lesions (ICDAS I and II)","pits and fissure sealants will be applied in initial carious enamel surfaces of posterior permanent teeth and the retention will the evaluated at 3, 6 , and 12 months.",[16],{"name":17,"affiliation":5,"role":18},"Dr. Fizza Sherazi, BDS","PRINCIPAL_INVESTIGATOR",[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Dr. Shoaib Rahim, FCPS","CONTACT","923215097582","clinicaltrials.fucd@fui.edu.pk",{"name":17,"role":22,"phone":26,"phoneExt":10,"email":27},"923242169131","fizzasherazi1998@gmail.com",[29],{"facility":5,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"RECRUITING","Islamabad","Federal","44000","Pakistan","PK",{"type":37,"coordinates":38},"Point",[39,40],73.04329,33.72148,{"lat":40,"lon":39},[43,47,50],{"name":44,"role":22,"phone":45,"phoneExt":10,"email":46},"Nadia Aman, BDS, FCPS","00923022526440","nadia.aman@fui.edu.pk",{"name":48,"role":22,"phone":49,"phoneExt":10,"email":24},"Shoaib Rahim, FCPS","00923215097582",{"name":51,"role":18,"phone":10,"phoneExt":10,"email":10},"Fizza Sherazi, BDS",{"type":18,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Shoaib Rahim","Associate Professor","100618320","retention-of-pits-and-fissure-sealants-on-non-carious-vs-initial-carious-enamel-lesions-in-posterior-teeth-100618320",false,"NCT07330089","Retention of Pits and Fissure Sealants on Non Carious vs Initial Carious Enamel Lesions in Posterior Teeth","Retention of Pits and Fissure Sealants on Non Carious vs Initial Carious Enamel Lesions in Posterior Teeth, a Non Randomized Clinical Study","Inclusion Criteria:\n\n* Fully erupted maxillary and mandibular 1st and 2nd molars with antagonist teeth present.\n* ICDAS score 0,I,II\n* Age 7 to 18 years\n* Both genders included\n\nExclusion Criteria:\n\n* permanent teeth requiring restorations,\n* uncooperative patients\n* patients unwilling for follow-ups\n* molars withy antagonist teeth not present\n* mentally and physically handicapped patients\n* patients with parafunctional habits\n* patients undergoing orthodontic treatments",true,"ALL","7 Years","18 Years",{"count":67,"type":68},420,"ESTIMATED","3 Months","OBSERVATIONAL","This clinical study is planned to be conducted to compare retention rates of pits and fissure sealants on non carious (ICDAS score 0) vs Initial carious enamel lesions (ICDAS Score 1,2) in posterior permeant teeth at 3 months, 6 months and 12 months follow-up. This will help us guide follow-up strategies for optimal caries prevention.",[73,74,75],"Dental Enamel","Dental Enamel Hypomineralization","Dental Enamel Hypoplasia",[77,78,79],"pit and fissure sealants","pit sealant","fissure sealant","2026-05-22",{"date":82,"type":83},"2026-05-26","ACTUAL",{"date":85,"type":83},"2025-12-27",{"date":87,"type":68},"2027-06-30",{"name":5,"class":6},1]