[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625829":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":21,"centralContacts":25,"locations":33,"responsibleParty":49,"collaborators":10,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":10,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":10,"studyType":66,"phases":10,"briefSummary":67,"conditions":68,"keywords":73,"overallStatus":82,"whyStopped":10,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Oslo University Hospital","OTHER",[8,12,15,18],{"label":9,"type":10,"description":11,"interventionNames":10},"Laser treated",null,"Subjects treated for ROP with laser of avascular retina",{"label":13,"type":10,"description":14,"interventionNames":10},"Control laser treated","Control subjects matched with subjects treated with laser",{"label":16,"type":10,"description":17,"interventionNames":10},"A-VEGF treated","Subjects treated for ROP with intravitreal injection of A-VEGF",{"label":19,"type":10,"description":20,"interventionNames":10},"Control A-VEGF treated","Control subjects matched with subjects treated with A-VEGF",[22],{"name":23,"affiliation":5,"role":24},"Erlend Christoffer Sommer Landsend, M.D., Ph.D.","STUDY_CHAIR",[26,30],{"name":23,"role":27,"phone":28,"phoneExt":10,"email":29},"CONTACT","0047 91 50 27 70","erllan@ous-hf.no",{"name":31,"role":27,"phone":28,"phoneExt":10,"email":32},"Amanda Schjetlein, M.D.","amasch@ous-hf.no",[34],{"facility":5,"status":10,"city":35,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Oslo","0424","Norway","NO",{"type":40,"coordinates":41},"Point",[42,43],10.74609,59.91273,{"lat":43,"lon":42},[46,48],{"name":47,"role":27,"phone":28,"phoneExt":10,"email":29},"Erlend C. S. Landsend, M.D., Ph.D.",{"name":31,"role":27,"phone":28,"phoneExt":10,"email":32},{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Erlend Christoffer Sommer Landsend","Senior consultant and researcher","100625829","retinopathy-of-prematurity---visual-function-and-retinal-structure-100625829",false,"NCT07427719","Retinopathy of Prematurity - Visual Function and Retinal Structure","Children Treated for Retinopathy of Prematurity - Study of Visual Function and Retinal Structure","Inclusion criteria:\n\n* Patients treated for ROP with either laser or injection of A-VEGF.\n* Patients previously diagnosed with ROP but not treated for the condition.\n\nExclusion criteria:\n\n* Age below six years at date of examination.\n* A developmental level not compatible with performing the study examinations.\n* Patients born or treated outside Norway\n* Known ocular or systemic disease that can give structural or functional changes in the retina.","ALL","6 Years","20 Years",{"count":64,"type":65},140,"ESTIMATED","OBSERVATIONAL","Children born prematurely may develop a characteristic retinal disease named retinopathy of prematurity (ROP). This disease could lead to retinal detachment and blindness. ROP was traditionally treated with laser, but injection with a medication (A-VEGF) has become more common.\n\nIn this study, the researchers will explore whether treatment of ROP affects visual function and retinal development. To explore this, the study group will examine children with ROP (but not treated) with children treated with either laser or injection. The researchers will compare the children's visual functions (e.g. visual acuity and visual field) and their retinas (e.g. central and peripheral retina).",[69,70,71,72],"Retinopathy of Prematurity (ROP)","Prematurity Complications","Cerebral Visual Impairment","Visual Field Defect",[74,75,76,77,78,79,80,81],"Retinopathy of Prematurity","Treatment","Laser","anti-vascular endothelial growth factor","Visual field defect","Cerebral visual impairment","Refractive errors","Prematurity","NOT_YET_RECRUITING","2026-02-16",{"date":85,"type":86},"2026-02-23","ACTUAL",{"date":88,"type":65},"2026-04-01",{"date":90,"type":65},"2029-06-01",{"name":5,"class":6},1]