[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632168":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":54,"collaborators":26,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":26,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":26,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":82,"whyStopped":26,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Sindh Institute of Urology and Transplantation","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A","ACTIVE_COMPARATOR","Group A will be comprised of those patients who will be treated by ESWL (shockwave lithotripsy).",[13],"Procedure: Extracorporeal shock wave lithotripsy",{"label":15,"type":16,"description":17,"interventionNames":18},"Group B","EXPERIMENTAL","Group B will be comprised of those patients who will be treated by RIRS (retrograde intrarenal surgery).",[19],"Procedure: Retrograde intrarenal surgery",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Retrograde intrarenal surgery","Retrograde intrarenal surgery (RIRS) is a minimally invasive procedure in which a flexible ureteroscope is passed through the urethra, then the ureter, and then into the kidney, and then with the help of the laser, stones are broken down into small fragments, which can be retrieved either at the same time or flushed later in urine. Stone clearance will assessed with an X-ray of the abdomen (radiopaque) and ultrasound or CT scan of the kidneys (residual radiolucent stones) on follow-up.",[15],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Extracorporeal shock wave lithotripsy","Extracorporeal shock wave lithotripsy (ESWL) is a noninvasive procedure in which highly focused shock waves are delivered at the renal calculi, which then break down into small pieces and later pass in urine. An X-ray abdomen (radiopaque) and ultrasound or CT scan of the kidneys (residual radiolucent stone) will be used on follow-up to assess stone clearance. Up to 3 sessions of ESWL will given to the selected candidate",[9],[32],{"name":33,"affiliation":5,"role":34},"Abdul Khaliq, FCPS","STUDY_DIRECTOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Maaz Nazir","CONTACT","+923122949655","maazbinnazir@yahoo.com",[42],{"facility":5,"status":26,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":26},"Karachi","Sindh","74200","Pakistan","PK",{"type":49,"coordinates":50},"Point",[51,52],67.0104,24.8608,{"lat":52,"lon":51},{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Maaz Bin Nazir","Resident","100632168","retrograde-intrarenal-surgery-versus-extracorporeal-shockwave-lithotripsy-100632168",false,"NCT07510178","Retrograde Intrarenal Surgery Versus Extracorporeal Shockwave Lithotripsy","Role Of Retrograde Intrarenal Surgery Versus Extracorporeal Shockwave Lithotripsy In Lower Calyceal Calculi","Inclusion Criteria\n\n* Those patients will be included with lower calyceal renal stones and size up to 1.5 cm.\n* Patients' ages will be between 18 and 60 years.\n* Both genders will be included.\n\nExclusion Criteria:\n\n* Untreated Urine culture positive will be excluded\n* Patients using anticoagulants and females with pregnancies and those lactating will be excluded.\n* Anatomical abnormalities like horseshoe kidney, duplex system, pelvic kidney, malrotated kidney, calyceal diverticulum, steep infundibulopelvic angle, infundibular stenosis, long infundibular length\u002Fnarrow infundibular width, pelvic ureteric junction obstruction, ureterocele, and ureteral stricture will be excluded.","ALL","18 Years","60 Years",{"count":69,"type":70},66,"ESTIMATED","INTERVENTIONAL",[73],"NA","The study's aim is to determine which treatment modality, either ESWL or RIRS, is more effective in achieving stone clearance for lower calyceal calculi.\n\nInvestigators hypothesize that retrograde intrarenal surgery is better as compared to extracorporeal shockwave lithotripsy. It will target those patients suffering from kidney stones in lower calyces with sizes up to 1.5 cm in an open-label, randomized controlled trial.",[76,77],"Renal Stone","Stone in Calyceal Diverticulum",[79,80,81],"renal stone","lithotripsy","retrograde","NOT_YET_RECRUITING","2026-04-10",{"date":85,"type":86},"2026-04-15","ACTUAL",{"date":88,"type":70},"2026-04-30",{"date":90,"type":70},"2026-10-30",{"name":5,"class":6},1]