[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645383":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":7,"locations":7,"responsibleParty":13,"collaborators":7,"id":15,"slug":16,"hasResults":17,"nctId":18,"briefTitle":19,"officialTitle":20,"acronym":7,"eligibilityCriteria":21,"healthyVolunteers":17,"sex":22,"minAge":23,"maxAge":7,"enrollmentInfo":24,"targetDuration":7,"studyType":27,"phases":7,"briefSummary":28,"conditions":29,"keywords":7,"overallStatus":33,"whyStopped":7,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":7},{"fullName":5,"class":6},"LOGEX","INDUSTRY",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"OTHER","Routine hospital care data (observational)","This is a non-interventional, retrospective observational study. No intervention is administered as part of this study. The study observes and analyses routinely collected hospital data on existing treatment patterns for Crohn's disease and ulcerative colitis, including conventional therapies and advanced systemic treatments (biologics, JAK inhibitors, S1P modulators), as prescribed in routine clinical care.",{"type":14,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100645383","retrospective-observational-multicenter-study-on-the-treatment-patterns-extra-intestinal-manifestations-resource-utilisation-and-outcomes-of-patients-with-inflammatory-bowel-disease-in-dutch-hospitals-100645383",false,"NCT07682038","Retrospective Observational Multicenter Study on the Treatment Patterns, Extra-Intestinal Manifestations, Resource Utilisation, and Outcomes of Patients With Inflammatory Bowel Disease in Dutch Hospitals","Treatment Patterns, Extra-Intestinal Manifestations, Resource Utilisation, and Outcomes of Patients With Inflammatory Bowel Disease in Dutch Hospitals","Inclusion Criteria:\n\n* Adult patients (≥18 years of age) who required secondary (hospital) care after January 2018 with a confirmed diagnosis of CD or UC, defined by at least one ICD-10 diagnosis code for CD or UC (K50, K51, K52).\n\nIndex date confirmation: the index date is defined as the first date of confirmed CD or UC diagnosis, requiring at least one healthcare encounter for CD or UC AND at least one prescription or dispensing record for any CD or UC-related medication within the observational period.\n\nExclusion Criteria:\n\n* Patients who have formally objected to the use of their hospital data for scientific research purposes. Objections are recorded by the treating hospital in the DBC administrative system and automatically transferred to the research dataset, ensuring automatic exclusion from all analyses.","ALL","18 Years",{"count":25,"type":26},3500,"ESTIMATED","OBSERVATIONAL","This multicenter retrospective real-world data study will evaluate the treatment pathways and disease burden of adult patients with Crohn's disease (CD) and ulcerative colitis (UC) treated in 5-10 Dutch hospitals between 2018 and 2026.\n\nThe study will assess:\n\n* Treatment sequences, switching patterns, and treatment duration\n* Prevalence and incidence of extra-intestinal manifestations (EIMs)\n* Healthcare resource utilization (hospitalizations, outpatient visits, endoscopies, surgery, and length of stay)\n* Direct healthcare costs\n* Availability of disease activity biomarkers\n\nUsing linked administrative, prescription, procedure, and laboratory data, outcomes will be analyzed by age, line of therapy, and clinical characteristics. Special focus will be placed on the impact of EIMs on treatment patterns, healthcare utilization, and costs.\n\nThe findings will provide real-world evidence on IBD management in the Netherlands and support clinical decision-making, healthcare planning, and future research on treatment optimization and coexisting immune-mediated conditions.",[30,31,32],"Crohn Disease","Inflammatory Bowel Disease (IBD)","Colitis Ulcerative","NOT_YET_RECRUITING","2026-06-26",{"date":36,"type":37},"2026-07-02","ACTUAL",{"date":39,"type":26},"2026-08-01",{"date":41,"type":26},"2027-06-30",{"name":5,"class":6}]