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Adults are defined as greater than or equal to, 18 years old. We will include adults with a confirmed diagnosis of COVID-19 or those with suspected or proven acute respiratory infection with onset within 14 days of ICU admission and requiring invasive mechanical ventilation, non-invasive ventilation, or high-flow oxygen therapy.",{"label":13,"type":10,"description":14,"interventionNames":10},"Pediatrics","Pediatric survivors of COVID-19, MIS-C, or acute respiratory infection admitted to participating pediatric intensive care units (PICUs). The investigators define children as less than 18 years old. We will include pediatric patients with COVID-19, those with multi-system inflammatory syndrome in children (MIS-C), and those with suspected or proven acute respiratory infection with onset within 14 days of ICU admission and requiring invasive mechanical ventilation, non-invasive ventilation, or high-flow oxygen therapy.",[16],{"name":17,"affiliation":5,"role":18},"Michelle E Kho, PT, PhD","PRINCIPAL_INVESTIGATOR",[20],{"name":21,"role":22,"phone":23,"phoneExt":24,"email":25},"Geoff Strong, PT, MS","CONTACT","905-522-1155","33242","revive@mcmaster.ca",[27,41,56,71,85,95,110,121,135,148,158,164,174,187,196,205,215,228,241,251,257,271,284,295,301,311,324,337],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":10},"Alberta Children's Hospital","ACTIVE_NOT_RECRUITING","Calgary","Alberta","T3B 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MSc","xxxxxxxxxx","jmslemko@ualberta.ca",{"facility":72,"status":58,"city":73,"state":74,"zip":75,"country":33,"countryCode":34,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"Royal Columbian Hospital","New Westminster","British Columbia","V3L 0A4",{"type":36,"coordinates":77},[78,79],-122.91092,49.20678,{"lat":79,"lon":78},[82],{"name":83,"role":22,"phone":69,"phoneExt":10,"email":84},"Steven Reynolds, MD","sreynolds.md@gmail.com",{"facility":86,"status":29,"city":87,"state":88,"zip":89,"country":33,"countryCode":34,"cosmosGeoPoint":90,"geoPoint":94,"contacts":10},"Children's Hospital of Winnipeg","Winnipeg","Manitoba","R3E 0Z3",{"type":36,"coordinates":91},[92,93],-97.14704,49.8844,{"lat":93,"lon":92},{"facility":96,"status":43,"city":97,"state":98,"zip":99,"country":33,"countryCode":34,"cosmosGeoPoint":100,"geoPoint":104,"contacts":105},"QEII Health Sciences Centre","Halifax","Nova Scotia","B3H 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Reeve","brendareeve@hotmail.ca",{"facility":136,"status":43,"city":137,"state":124,"zip":138,"country":33,"countryCode":34,"cosmosGeoPoint":139,"geoPoint":143,"contacts":144},"Hamilton General Hospital","Hamilton","L8L 2X2",{"type":36,"coordinates":140},[141,142],-79.84963,43.25011,{"lat":142,"lon":141},[145],{"name":146,"role":22,"phone":10,"phoneExt":10,"email":147},"Maureen Meade","meade.maureen@gmail.com",{"facility":149,"status":43,"city":137,"state":124,"zip":150,"country":33,"countryCode":34,"cosmosGeoPoint":151,"geoPoint":153,"contacts":154},"St. Joseph's Healthcare Intensive Care Unit","L8N 4A6",{"type":36,"coordinates":152},[141,142],{"lat":142,"lon":141},[155],{"name":156,"role":22,"phone":10,"phoneExt":10,"email":157},"Michelle Kho, PT, PhD","khome@mcmaster.ca",{"facility":159,"status":29,"city":137,"state":124,"zip":160,"country":33,"countryCode":34,"cosmosGeoPoint":161,"geoPoint":163,"contacts":10},"McMaster Children's Hospital","L8S 4K1",{"type":36,"coordinates":162},[141,142],{"lat":142,"lon":141},{"facility":165,"status":43,"city":137,"state":124,"zip":166,"country":33,"countryCode":34,"cosmosGeoPoint":167,"geoPoint":169,"contacts":170},"Juravinski Hospital","L8V 1C3",{"type":36,"coordinates":168},[141,142],{"lat":142,"lon":141},[171],{"name":172,"role":22,"phone":10,"phoneExt":10,"email":173},"Bram Rochwerg","bram.rochwerg@gmail.com",{"facility":175,"status":43,"city":176,"state":124,"zip":177,"country":33,"countryCode":34,"cosmosGeoPoint":178,"geoPoint":182,"contacts":183},"Kingston Health Sciences Centre","Kingston","K7L 2V7",{"type":36,"coordinates":179},[180,181],-76.48098,44.22976,{"lat":181,"lon":180},[184],{"name":185,"role":22,"phone":10,"phoneExt":10,"email":186},"John Muscedere","John.Muscedere@kingstonhsc.ca",{"facility":188,"status":29,"city":189,"state":124,"zip":190,"country":33,"countryCode":34,"cosmosGeoPoint":191,"geoPoint":195,"contacts":10},"London Health Sciences Centre","London","N6A 5W9",{"type":36,"coordinates":192},[193,194],-81.23304,42.98339,{"lat":194,"lon":193},{"facility":197,"status":29,"city":198,"state":124,"zip":199,"country":33,"countryCode":34,"cosmosGeoPoint":200,"geoPoint":204,"contacts":10},"Children's Hospital of Eastern Ontario","Ottawa","K1H 8L1",{"type":36,"coordinates":201},[202,203],-75.69812,45.41117,{"lat":203,"lon":202},{"facility":206,"status":43,"city":198,"state":124,"zip":207,"country":33,"countryCode":34,"cosmosGeoPoint":208,"geoPoint":210,"contacts":211},"The Ottawa Hospital","K1H 8L6",{"type":36,"coordinates":209},[202,203],{"lat":203,"lon":202},[212],{"name":213,"role":22,"phone":10,"phoneExt":10,"email":214},"Andrew Seely","aseely@toh.ca",{"facility":216,"status":43,"city":217,"state":124,"zip":218,"country":33,"countryCode":34,"cosmosGeoPoint":219,"geoPoint":223,"contacts":224},"Niagara Health System","St. Catharines","L2S 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Burns","Karen.Burns@unityhealth.to",{"facility":252,"status":29,"city":230,"state":124,"zip":253,"country":33,"countryCode":34,"cosmosGeoPoint":254,"geoPoint":256,"contacts":10},"The Hospital for Sick Children","M5G 1E8",{"type":36,"coordinates":255},[234,235],{"lat":235,"lon":234},{"facility":258,"status":43,"city":259,"state":260,"zip":261,"country":33,"countryCode":34,"cosmosGeoPoint":262,"geoPoint":266,"contacts":267},"Hôpital Hôtel-Dieu de Lévis","Lévis","Quebec","G6V 3Z1",{"type":36,"coordinates":263},[264,265],-71.17793,46.80326,{"lat":265,"lon":264},[268],{"name":269,"role":22,"phone":10,"phoneExt":10,"email":270},"Patrick Archambault","patrick.m.archambault@gmail.com",{"facility":272,"status":43,"city":273,"state":260,"zip":274,"country":33,"countryCode":34,"cosmosGeoPoint":275,"geoPoint":279,"contacts":280},"Centre hospitalier de l'Université de Montréal","Montreal","H2X 3E4",{"type":36,"coordinates":276},[277,278],-73.58781,45.50884,{"lat":278,"lon":277},[281],{"name":282,"role":22,"phone":10,"phoneExt":10,"email":283},"Han Ting Wang","ht.wang@umontreal.ca",{"facility":285,"status":58,"city":273,"state":260,"zip":286,"country":33,"countryCode":34,"cosmosGeoPoint":287,"geoPoint":289,"contacts":290},"The Centre hospitalier universitaire Sainte-Justine","H3T 1C5",{"type":36,"coordinates":288},[277,278],{"lat":278,"lon":277},[291],{"name":292,"role":22,"phone":293,"phoneExt":10,"email":294},"Laurence Ducharme-Crevier, MD, MSc","5143454931","laurence.ducharme.crevier.med@ssss.gouv.qc.ca",{"facility":296,"status":29,"city":273,"state":260,"zip":297,"country":33,"countryCode":34,"cosmosGeoPoint":298,"geoPoint":300,"contacts":10},"Montreal Children's Hospital","H4A 3J1",{"type":36,"coordinates":299},[277,278],{"lat":278,"lon":277},{"facility":302,"status":43,"city":273,"state":260,"zip":303,"country":33,"countryCode":34,"cosmosGeoPoint":304,"geoPoint":306,"contacts":307},"Hôpital du Sacré-Cœur de Montréal","H4J 1C5",{"type":36,"coordinates":305},[277,278],{"lat":278,"lon":277},[308],{"name":309,"role":22,"phone":10,"phoneExt":10,"email":310},"Karim Serri","karimserri@hotmail.com",{"facility":312,"status":43,"city":313,"state":260,"zip":314,"country":33,"countryCode":34,"cosmosGeoPoint":315,"geoPoint":319,"contacts":320},"Institut Universitaire de Cardiologie et de Pneumologie de Québec","Québec","G1V 4G5",{"type":36,"coordinates":316},[317,318],-71.21454,46.81228,{"lat":318,"lon":317},[321],{"name":322,"role":22,"phone":10,"phoneExt":10,"email":323},"Patricia Lizotte","patricia.lizotte@criucpq.ulaval.ca",{"facility":325,"status":43,"city":326,"state":260,"zip":327,"country":33,"countryCode":34,"cosmosGeoPoint":328,"geoPoint":332,"contacts":333},"Hôpital Fleurimont - Sherbrooke","Sherbrooke","J1H 5H3",{"type":36,"coordinates":329},[330,331],-71.89908,45.40008,{"lat":331,"lon":330},[334],{"name":335,"role":22,"phone":10,"phoneExt":10,"email":336},"Frederick D'Aragon","Frederick.DAragon@USherbrooke.ca",{"facility":338,"status":43,"city":339,"state":340,"zip":10,"country":33,"countryCode":34,"cosmosGeoPoint":341,"geoPoint":345,"contacts":346},"Saskatchewan Health Authority","Regina","Saskatchewan",{"type":36,"coordinates":342},[343,344],-104.6178,50.45008,{"lat":344,"lon":343},[347],{"name":348,"role":22,"phone":10,"phoneExt":10,"email":349},"Eric Sy","eric.julian.sy@gmail.com",{"type":351,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[353,356],{"name":354,"class":355},"Canadian Institutes of Health Research (CIHR)","OTHER_GOV",{"name":357,"class":6},"Canadian Critical Care Trials Group","100458167","revive-frailty-rehabilitation-and-outcomes-in-critically-ill-adult-and-pediatric-survivors-of-covid-19-or-ari-100458167",false,"NCT05246098","REVIVe: Frailty, Rehabilitation, and Outcomes in Critically Ill Adult and Pediatric Survivors of COVID-19 or ARI","REVIVe: Frailty, Rehabilitation, and Outcomes in Critically Ill Adult and Pediatric Survivors of COVID-19 or Acute Respiratory Infection","REVIVe","Inclusion Criteria:\n\n* Adult and pediatric survivors of COVID-19 or acute respiratory infection admitted to participating intensive care units (ICUs) and PICUs. The investigators define children as less than, and adults as greater than or equal to, 18 years old, respectively. The investigators will include adults and pediatrics with a confirmed diagnosis of COVID-19, pediatric patients with MIS-C, and adults and pediatrics with suspected or proven acute respiratory infection with onset within 14 days of ICU\u002FPICU admission and requiring invasive mechanical ventilation, non-invasive ventilation, or high flow oxygen therapy.\n\nExclusion Criteria:\n\n* Patients who were admitted to ICU for \\\u003C24 hours","ALL",{"count":368,"type":369},900,"ESTIMATED","OBSERVATIONAL","Background: Many adults and some children with COVID-19 or acute respiratory infection become critically ill and need advanced life support in the Intensive Care Unit (ICU). Frailty is a medical condition of reduced function and health. Adults with frailty have a lower chance of surviving critical illness. The investigators are still learning about critically ill adults with COVID-19 or acute respiratory infection, and do not have much information on how frailty affects outcomes in critically ill children, with or without COVID-19 or acute respiratory infection. Rehabilitation can help survivors of COVID-19 or acute respiratory infection by improving strength and improve quality of life (QOL).\n\nObjectives: The main goal of this research study is to see if patients with frailty have a lower chance of surviving COVID-19 or acute respiratory infection critical illness and more health problems after survival than patients without frailty. The investigators will also study the types of rehabilitation received by patients with COVID-19 or acute respiratory infection.\n\nMethods: The investigators will include adults and children with COVID-19 or acute respiratory infection who are admitted to the ICUs that participate in the study. The investigators will gather data about each patient, including before and during their illness.\n\nOutcomes: The investigators will collect level of frailty, function, and types of therapy, or rehabilitation received by patients. In adults, the investigators are most interested in learning if frailty influences mortality, or death. In children, the investigators are most interested in whether children with COVID-19 or acute respiratory infection critical illness are more likely to develop frailty. The investigators will also study post-hospital discharge location in survivors (e.g., home, rehabilitation).\n\nRelevance: The COVID-19 pandemic is a global public health crisis. It is critical to understand how COVID-19 and other acute respiratory infection critical illness affects groups of people who are at higher risk, and the impact on outcomes that are important to patients, like functioning and QOL. The results will help policy makers plan post-hospital services for survivors, help healthcare workers understand the importance of rehabilitation practice for patients with COVID-19 or acute respiratory infection, and help researchers develop treatments to improve QOL after COVID-19 or acute respiratory infection.",[373,374,375],"Respiratory Disease","COVID-19","Viral Infection","2024-11-04",{"date":378,"type":379},"2024-11-06","ACTUAL",{"date":381,"type":379},"2022-08-24",{"date":383,"type":369},"2025-10-01",{"name":5,"class":6},28]