[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100308627":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":28,"responsibleParty":60,"collaborators":10,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":75,"studyType":76,"phases":10,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"University of Colorado, Denver","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"RA with Sub-clinical ILD",null,"Subjects will be followed annually until study closure.\n\nAssessments are as follows:\n\n1. Clinical (Annual): Demographics, health-related behaviors, co-morbidities, medications, respiratory symptoms, rheumatologic assessment, quality of life\n2. Physiologic (3-5 yrs FU): Lung function on Pulmonary Function Test (PFT)\n3. Radiologic (3-5 yrs FU): HRCT scan of chest\n4. Genetic (3-5 yrs FU): Blood sample collection for RNA\n5. Biologic (3-5 yrs FU): Blood sample collection for other blood markers",{"label":13,"type":10,"description":14,"interventionNames":10},"RA with No-ILD","Subjects will be followed annually until study closure.\n\nAssessments are as follows:\n\n1. Clinical (Annual): Demographics, health-related behaviors, co-morbidities, medications, respiratory symptoms, rheumatologic assessment, quality of life\n2. Physiologic (3-5 yrs FU): Lung function on Pulmonary Function Test (PFT)\n3. Radiologic (3-5 yrs FU): HRCT scan of chest\n4. Genetic (3-5 yrs FU): Blood sample collection for RNA\n5. Biologic (3-5 yrs FU): Blood sample collection for other blood markers\n\nNote: Certain follow-up procedures may not occur for every subject and will be determined by the research team.",[16],{"name":17,"affiliation":5,"role":18},"Joyce S Lee, MD","PRINCIPAL_INVESTIGATOR",[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Haylie A Lengel","CONTACT","970-376-8303","haylie.lengel@cuanschutz.edu",{"name":17,"role":22,"phone":26,"phoneExt":10,"email":27},"303-724-6109","joyce.lee@ucdenver.edu",[29],{"facility":30,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"University of Colorado - Anschutz Medical Campus","RECRUITING","Aurora","Colorado","80045","United States","US",{"type":38,"coordinates":39},"Point",[40,41],-104.83192,39.72943,{"lat":41,"lon":40},[44,45,49,51,54,56,58],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},{"name":46,"role":22,"phone":47,"phoneExt":10,"email":48},"Elizabeth O'Brien","303-875-1844","elizabeth.a.obrien@cuanschutz.edu",{"name":50,"role":18,"phone":10,"phoneExt":10,"email":10},"Joce Lee, MD",{"name":52,"role":53,"phone":10,"phoneExt":10,"email":10},"Kristen Demoruelle, MD","SUB_INVESTIGATOR",{"name":55,"role":53,"phone":10,"phoneExt":10,"email":10},"Jason Kolfenbach, MD",{"name":57,"role":53,"phone":10,"phoneExt":10,"email":10},"Duane Pearson, MD",{"name":59,"role":53,"phone":10,"phoneExt":10,"email":10},"Kevin Deane, MD",{"type":61,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100308627","rheumatoid-arthritis-patients-at-risk-for-interstitial-lung-disease-100308627",false,"NCT03297775","Rheumatoid Arthritis Patients at Risk for Interstitial Lung Disease","RAPID","Inclusion Criteria:\n\n1. ≥ 45years old\n2. Diagnosis of RA using the 2010 American College of Rheumatology (ACR) criteria\n\nExclusion Criteria:\n\n1. Inability to give informed consent\n2. Pregnant women\n3. History of interstitial lung disease\n4. Evidence of other causes of diffuse parenchymal lung disease such as infection, drug toxicity, other autoimmune processes, etc.\n5. Subjects over the age of 90 years old or less than 45 years old","ALL","45 Years","90 Years",{"count":73,"type":74},750,"ESTIMATED","5 Years","OBSERVATIONAL","The overall goal of this study is to define the phenotype of Interstitial Lung Disease (ILD), and identify factors that predict radiologic progression in those with subclinical RA-ILD, in patients with rheumatoid arthritis (RA). The investigators hypothesize that there are common core elements (e.g. clinical features, genetic variants, and\u002For biologic markers) between other forms of ILD (e.g. idiopathic pulmonary fibrosis, IPF) and subclinical RA-ILD that places individuals at risk for the development of lung disease.",[79,80],"Rheumatoid Arthritis","Interstitial Lung Disease",[79,82,80,83,84,85,86,87,88,89],"RA","ILD","lung disease","connective tissue disease","CTD","idiopathic pulmonary fibrosis","IPF","airways disease","2026-04-27",{"date":92,"type":93},"2026-05-01","ACTUAL",{"date":95,"type":93},"2017-06-22",{"date":97,"type":74},"2027-06",{"name":5,"class":6},1]