[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638666":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":29,"locations":39,"responsibleParty":53,"collaborators":24,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":59,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":24,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":42,"whyStopped":24,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"University of Faisalabad","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Rhythmic Initiation Group","EXPERIMENTAL","Participants receive Rhythmic Initiation technique for the affected upper limb. Each 30-minute session follows a sequence: passive movement, active-assistive movement, active movement, and light resisted movement using PNF diagonal patterns (D1 or D2). Sessions occur 5 days per week for 4 weeks.",[13],"Other: Rhythmic Initiation (PNF technique)",{"label":15,"type":10,"description":16,"interventionNames":17},"Isometric Resistance Training Group","Participants receive isometric strengthening exercises for upper limb muscles (shoulder abductors, elbow flexors\u002Fextensors, wrist flexors\u002Fextensors). Contractions held 6-10 seconds at 60-70% MVC, 10 repetitions × 3 sets. Sessions occur 30 minutes, 5 days\u002Fweek for 4 weeks.",[18],"Other: Isometric Resistance Training",[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Rhythmic Initiation (PNF technique)","What: Rhythmic Initiation technique from PNF. How: Therapist guides patient's affected upper limb through a four-step sequence-passive movement (therapist moves limb), active-assistive movement (patient helps with therapist assistance), active movement (patient moves independently), and light resisted movement (therapist adds gentle resistance). The movement follows PNF diagonal pattern D1 (flexion-adduction-external rotation to extension-abduction-internal rotation) or D2. Verbal cues emphasize smooth, rhythmic motion. When: 30 minutes per session, 5 days per week. How long: 4 weeks total. By whom: Trained physical therapist. Where: Outpatient rehabilitation department.",[9],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Isometric Resistance Training","What: Isometric Resistance Training (static muscle contractions without joint movement). How: Patient contracts target muscle against resistance provided by therapist or stationary object. Target muscles include shoulder abductors, elbow flexors, elbow extensors, wrist flexors, and wrist extensors. Each contraction held 6-10 seconds at 60-70% of maximum voluntary contraction. Patient performs 10 repetitions per muscle group, completing 3 sets. Rest 30-60 seconds between sets. When: 30 minutes per session, 5 days per week. How long: 4 weeks total. By whom: Trained physical therapist. Where: Outpatient rehabilitation department.",[15],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"Dr Marium Zafar, MS-NMPT","CONTACT","+92 300 4561972","mariumzafar.dpt@tuf.edu.pk",{"name":36,"role":32,"phone":37,"phoneExt":24,"email":38},"Dr Muhammad Ateeb, PhD Public Health","+923357333383","mateeb.oric@tuf.edu.pk",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":24,"geoPoint":24,"contacts":48},"The University of Faisalabad","RECRUITING","Faisalābad","Punjab Province","3800","Pakistan","PK",[49],{"name":50,"role":32,"phone":51,"phoneExt":24,"email":52},"Dr Anbreena Rasool, Doctor of Physical Therapy","+92 345 7936825","anbreenarasool.DPT@tuf.edu.pk",{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Dr. Marium Zafar","Assistant Professor, Department of Rehabilitation Sciences","100638666","rhythmic-initiation-vs-isometric-training-for-arm-recovery-after-stroke-100638666",false,"NCT07598435","Rhythmic Initiation vs Isometric Training for Arm Recovery After Stroke","Comparative Effects of Rhythmic Initiation and Isometric Resistance Training on Upper Limb Motor Function, Strength, and Coordination in Subacute Stroke Patients","RIITSTROKE","Inclusion Criteria:\n\n* Clinically diagnosed subacute stroke (1 to 6 months post-onset)\n* Unilateral upper limb involvement\n* Age 40 to 60 years\n* Both genders\n* Medically stable and able to participate in physical therapy\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Severe spasticity (Modified Ashworth Scale score \\>3)\n* Recurrent or bilateral stroke\n* Shoulder subluxation\n* Shoulder or upper limb pain limiting active movement\n* Cognitive or perceptual deficits impairing ability to follow instructions\n* Other neurological disorder affecting upper limb (e.g., Parkinson's disease, multiple sclerosis)\n* Orthopedic condition affecting upper limb function","ALL","40 Years","60 Years",{"count":69,"type":70},40,"ESTIMATED","INTERVENTIONAL",[73],"NA","Stroke is a leading cause of long-term disability worldwide. Many stroke survivors experience persistent weakness, loss of motor control, and poor coordination in their upper limb, which limits their ability to perform daily activities and return to independent living. This study compares two physical therapy approaches for patients in the subacute stage of stroke recovery (1 to 6 months after stroke). The first approach is Rhythmic Initiation, a technique from Proprioceptive Neuromuscular Facilitation (PNF) that uses smooth, guided movement patterns progressing from passive to active movement. The second approach is Isometric Resistance Training, which involves holding static muscle contractions against resistance without moving the joint. The study will enroll 40 patients aged 40 to 60 years with unilateral upper limb weakness from a first-time stroke. Participants will be randomly assigned to receive either Rhythmic Initiation or Isometric Resistance Training for 30 minutes per session, 5 days per week, for 4 weeks. The researchers will measure changes in motor function, muscle strength, coordination, and spasticity before and after the 4-week intervention. The results will help physiotherapists understand which approach is more effective for upper limb rehabilitation in subacute stroke patients.",[76,77],"Stroke","Upper Extremity Paresis",[79,80,81,82,83],"Stroke Rehabilitation","PNF","Isometric Exercise","Upper Limb","Motor Function","2026-06-01",{"date":86,"type":87},"2026-06-03","ACTUAL",{"date":89,"type":87},"2026-01-19",{"date":91,"type":70},"2026-06-24",{"name":5,"class":6},1]