[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100435779":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":24,"centralContacts":28,"locations":38,"responsibleParty":57,"collaborators":24,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":24,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":24,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":41,"whyStopped":24,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"University of Alabama at Birmingham","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Allograft particles hydrated with rhPDGF","EXPERIMENTAL","Allograft particles should be hydrated with GEM21S for 20 minutes prior to grafting. The graft sites will be covered with a resorbable barrier membrane.",[13],"Biological: Allograft particles hydrated with rhPDGF",{"label":15,"type":16,"description":17,"interventionNames":18},"Allograft particles hydrated in a conventional way with saline.","ACTIVE_COMPARATOR","Allograft particles should be hydrated with saline for 20 minutes prior to grafting. The graft sites will be covered with a resorbable barrier membrane.",[19],"Biological: Allograft particles hydrated in a conventional way with saline.",[21,25],{"type":22,"name":9,"description":11,"armGroupLabels":23,"otherNames":24},"BIOLOGICAL",[9],null,{"type":22,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Allograft particles should be hydrated with saline for 20 minutes prior to grafting. The graft sites will be covered with a resorbable barrier membrane",[15],[29,34],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Hussein Basma, DDS, MS","CONTACT","205-934-2888","basma86@uab.edu",{"name":35,"role":31,"phone":36,"phoneExt":24,"email":37},"Sarah Startley, DMD","205-975-8711","ss1971@uab.edu",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Unversity of Alabama at Birmingham, School of Dentistry","RECRUITING","Birmingham","Alabama","35294-0007","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-86.80249,33.52066,{"lat":51,"lon":50},[54,56],{"name":30,"role":31,"phone":55,"phoneExt":24,"email":33},"205-975-2888",{"name":35,"role":31,"phone":36,"phoneExt":24,"email":37},{"type":58,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Hussein Basma","Principal Investigator","100435779","ridge-augmentation-using-allograft-particles-hydrated-with-or-without-recombinant-human-platelet-derived-growth-factor-100435779",false,"NCT04954664","Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor","Lateral Ridge Augmentation Using Allograft Bone Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor: A Clinical and Histological Randomized Controlled Trial","Inclusion Criteria:\n\n* English speaking\n* At least 18 years old\n* Must be a patient of the UAB Dental School\n* Able to read and understand informed consent document\n* Need for implants to replace missing tooth or teeth in at least one quadrant of the mouth.\n* Insufficient alveolar ridge width for endosseous implant placement defined as 5mm or less as determined by bone sounding and cone beam computed tomography (CBCT) scan.\n\nExclusion Criteria:\n\n* Non-English speaking\n* Less than 18 years old\n* Smokers\u002Ftobacco users (\\>10 cigarettes\u002Fday)\n* Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing\n* Patient is a poor compliance risk (i.e., poor oral hygiene, history of alcohol or drug abuse)\n* Vertical loss of bone at edentulous ridge.",true,"ALL","18 Years","99 Years",{"count":73,"type":74},44,"ESTIMATED","INTERVENTIONAL",[77],"NA","This study will compare two techniques to achieve increase in ridge dimensions as a preparation for dental implants using a resorbable barrier membrane and bone particulate allogenic graft hydrated with saline or a growth factor called Recombinant Human Platelet-Derived Growth Factor (rhPDGF).",[80,81],"Dental Implant","Bone Loss",[83,84],"New bone","Dental implants","2025-12-19",{"date":87,"type":88},"2025-12-29","ACTUAL",{"date":90,"type":88},"2021-08-11",{"date":92,"type":74},"2027-12",{"name":5,"class":6},1]