[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639949":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":23,"locations":29,"responsibleParty":43,"collaborators":10,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":10,"eligibilityCriteria":52,"healthyVolunteers":49,"sex":53,"minAge":54,"maxAge":10,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":10,"overallStatus":65,"whyStopped":10,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"Laval University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Retrospective cohort",null,"Completed study. Adult patients who underwent cardiac surgery were included if they were admitted to the intensive care unit immediately after surgery, mechanically ventilated in controlled mode, and had an arterial blood gas within the first hour following admission.",[13],"Other: Not applicable- observational study",{"label":15,"type":10,"description":16,"interventionNames":17},"Prospective cohort","Completed study. Adult patient included on open-label randomized study, comparing clinician-chosen initial mechanical ventilation parameters to those recommended by an algorithm immediately after ICU admission.",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Not applicable- observational study","No intervention",[15,9],[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Etienne Couture","CONTACT","1-418-656-8711","etienne.couture.3@ulaval.ca",[30],{"facility":31,"status":10,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":10},"Institut universitaire de cardiologie et de pneumologie de Quebec - Universite Laval","Québec","Quebec","G1V4G5","Canada","CA",{"type":38,"coordinates":39},"Point",[40,41],-71.21454,46.81228,{"lat":41,"lon":40},{"type":44,"investigatorFullName":45,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","François Lellouche","Co-Investigator","100639949","right-ventricular-function-and-respiratory-acidosis-after-cardiac-surgery-100639949",false,"NCT07619274","Right Ventricular Function and Respiratory Acidosis After Cardiac Surgery","Inclusion Criteria:\n\n* Previously included and complete study NCT05886413 or NCT06826794\n\nExclusion Criteria:\n\n* Absence of one or more of the following hemodynamic measurements: systolic or diastolic pulmonary artery pressure, central venous pressure, cardiac output\n* Absence of arterial blood gas on arrival to the intensive care unit","ALL","18 Years",{"count":56,"type":57},220,"ESTIMATED","OBSERVATIONAL","Right heart dysfunction remains a frequent cause of morbidity and mortality after cardiac surgery. Respiratory acidosis, particularly when accompanied by hypoxemia, plays a significant role in right heart failure, primarily by increasing right ventricular afterload through pulmonary vasoconstriction and elevated pulmonary arterial pressures. This phenomenon leads to increased right ventricular workload, causing dilation, decreased contractility, and ultimately right heart failure. The study aims to evaluate the effect of respiratory acidosis on right ventricular function after cardiac surgery.",[61,62,63,64],"Respiratory Acidosis in ICU Patients","Right Ventricular (RV) Dysfunction","Hemodynamic Changes","Mechanical Ventilation","NOT_YET_RECRUITING","2026-05-28",{"date":68,"type":69},"2026-06-01","ACTUAL",{"date":71,"type":57},"2026-05",{"date":73,"type":57},"2026-10",{"name":5,"class":6},1]